Results 21 to 30 of about 46,645 (191)
RNA N6-methyladenosine: a promising molecular target in metabolic diseases
Cell & Bioscience, 2020 N6-methyladenosine is a prevalent and abundant transcriptome modification, and its methylation regulates the various aspects of RNAs, including transcription, translation, processing and metabolism.
Yan Li +5 more
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, 2022 Accumulating evidence indicates that N6-methyladenosine (m6A) and long noncoding RNAs (lncRNAs) play crucial roles in cancer development. However, the biological roles of m6A and lncRNAs in lung cancer tumorigenesis are largely unknown.
Liang Zhu (172992) +3 more
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Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancer
Cancer Biology & Medicine, 2020 The biological roles of N6 methylation of nucleic acids have been extensively studied. Adenine methylation of RNA is the most prevalent RNA modification and has widespread effects on RNA splicing, translation, localization, and stability.
Zhixian Liang +3 more
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Epigenetic regulation of N6‐methyladenosine modifications in obesity
Journal of Diabetes Investigation, 2021 Obesity is a serious health issue in the world and is related to a higher risk of suffering metabolic diseases. Understanding the molecular basis of obesity is critical to identify new targets to treat obesity and obesity‐associated metabolic diseases ...
Mingli Sun, Xinan Zhang
doaj +1 more source
, 2021 As one of the most common forms of RNA modification, N6-methyladenosine (m6A) RNA modification has attracted increasing research interest in recent years.
Lihong Yin (328532) +9 more
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Isothermal Amplification-Based Detection of Single-Base RNA N6-Methyladenosine
, 2023 N6-methyladenosine (m6A) has recently gained much attention due to its diverse biological functions. Currently, the commonly used detection methods for locus-specific m6A marks are complicated to operate, it is difficult to quantify the methylation level,
Cheng Yi (4502179) +11 more
core +1 more source
N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication
Frontiers in Cell and Developmental Biology, 2021 N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV).
Fabian Figueroa +15 more
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, 2021 The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439) +7 more
core +1 more source
, 2021 The role of N6-methyladenosine (m6A)-modifying proteins in cancer progression depends on the cell type and mRNA affected. However, the biological role and underlying mechanism of m6A in kidney cancer is limited. Here, we discovered the variability in m6A
Zijuan Xin (11472439) +7 more
core +1 more source
N6‐methyladenosine Steers RNA Metabolism and Regulation in Cancer
Cancer Communications, 2021 As one of the most studied ribonucleic acid (RNA) modifications in eukaryotes, N6‐methyladenosine (m6A) has been shown to play a predominant role in controlling gene expression and influence physiological and pathological processes such as oncogenesis ...
Shenghua Dong +4 more
doaj +1 more source