The Role of One‐Carbon Metabolism in Cancer and Its Therapeutic Significance
MedComm – Oncology, Volume 5, Issue 1, March 2026.One‐Carbon metabolism in T‐cell activation and tumor competition. T‐cell activation shifts metabolic pathways, promoting anabolic metabolism and bioenergetic capacity. One‐carbon metabolism plays a crucial role in histone and DNA methylation in activated T cells.
Yuting Jiang +3 more
wiley +1 more source
Expanding the diversity of DNA base modifications with N 6-methyldeoxyadenosine [PDF]
, 2016 Kate D. Meyer, Samie R. Jaffrey
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The exposomal imprint on rosacea: More than skin deep
Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 3, Page 387-403, March 2026.Rosacea reflects systemic and environmental interactions, not just a skin disorder. Key factors include environmental triggers, genetic and microbiome influences, diagnostic gaps in skin of colour and social determinants. Advances in multi‐omics and exposome integration highlight pathways towards precision medicine, prevention and equitable, patient ...
Katerina Grafanaki +3 more
wiley +1 more source
BMC NephrologyObjective Diabetic kidney disease (DKD) is increasingly recognized as a leading cause of chronic kidney disease (CKD) worldwide. Although N6-methyladenosine (m6A) mRNA modification is abundant in eukaryotes, its specific contribution to DKD pathogenesis ...
Meng Leilei +3 more
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The crosstalk between N6‐methyladenosine readers and neuroblastoma
Clinical and Translational DiscoveryBackground Neuroblastoma (NB) is a heterogeneous pediatric solid tumour strongly influenced by epigenetic modifications. Methods This review explores the role of N6‐methyladenosine (m6A) modifications and their readers in NB progression.
Liping Chen, Jing He, Zhenjian Zhuo
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N6-methyladenosine (m6A) modification in osteosarcoma: expression, function and interaction with noncoding RNAs - an updated review. [PDF]
Epigenetics, 2023 Zhang Y +9 more
europepmc +1 more source
Enhancing sensitivity of triple-negative breast cancer to DNA damaging therapy through chemical inhibition of the m6A methyltransferase METTL3 [PDF]
Among the different types of breast cancer, triple-negative breast cancer (TNBC) displays the most unfavourable prognosis and high risk of recurrence. Conventional chemotherapy and DNA damaging agents are the main treatment for this cancer. However, this
CESARO, BIANCA
core
N6-methyladenosine (m6A) regulates signaling pathways during early embryo development
, 2022 N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic mRNA. In recent years, a slew of interesting studies had confirmed its essential role as a post-transcriptional regulator of gene expression in a wide range of biological processes, especially during development.
openaire +2 more sources
Recent Advances in the Mutual Regulation of m6A Modification and Non-Coding RNAs in Atherosclerosis
International Journal of General MedicineYanlu Wang, Sisi Ling, Hao Feng, Junkai Hua, Zhiyu Han, Renjie Chai Department of Cardiology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, 510260, People’s Republic of ChinaCorrespondence: Renjie Chai ...
Wang Y +5 more
doaj
Retracted: The N6-Methyladenosine- (m6A-) Associated Genes Act as Strong Key Biomarkers for the Prognosis of Pancreatic Adenocarcinoma. [PDF]
Comput Math Methods Med, 2023 Methods In Medicine CAM.
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