Results 201 to 210 of about 23,000 (243)

When animal viruses meet N6-methyladenosine (m6A) modifications: for better or worse? [PDF]

open access: yesVet Res
Wang W   +8 more
europepmc   +1 more source

Global mapping of RNA N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) in human subcutaneous and visceral adipose tissue reveals novel targets that correlate with clinical variables of obesity. [PDF]

open access: yesBiomark Res
Rønningen T   +17 more
europepmc   +1 more source
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N6‐methyladenosine (m6A) modification in gynecological malignancies

Journal of Cellular Physiology, 2022
AbstractN6‐methyladenosine (m6A) modification is one of the most abundant modifications in eukaryotic mRNA, regulated by m6A methyltransferase and demethylase. m6A modified RNA is specifically recognized and bound by m6A recognition proteins, which mediate splicing, maturation, exonucleation, degradation, and translation.
Ning Liu
exaly   +3 more sources

N6‐methyladenosine (m6A) Modification in Preeclampsia

Reproductive Sciences, 2023
Recently, epitranscriptional modification of N6-methyladenosine (m6A) has received growing attention in the research on the pathogenesis of preeclampsia. Advances in m6A sequencing have revealed the molecular mechanism and importance of m6A modification.
Tingting Zhang   +6 more
openaire   +2 more sources

The role of N6-methyladenosine (m6A) in eye diseases

Molecular Biology Reports, 2021
N6-methyladenosine (m6A) is the most common form of internal RNA modification in eukaryotes. The dynamic regulation of m6A modification mainly rely on three proteases, installed by m6A methyltransferase, removed by m6A demethylase and recognized by m6A reader protein, which regulates the metabolism of RNA, thereby regulating the processes of cell ...
Jing-Fan Gao, Lu Zhang
openaire   +2 more sources

N6-methyladenosine (m6A) methylation in kidney diseases: Mechanisms and therapeutic potential

open access: yesBiochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2023
The N6-methyladenosine (m6A) modification is regulated by methylases, commonly referred to as "writers," and demethylases, known as "erasers," leading to a dynamic and reversible process. Changes in m6A levels have been implicated in a wide range of cellular processes, including nuclear RNA export, mRNA metabolism, protein translation, and RNA splicing,
Yuting, Sun   +13 more
exaly   +3 more sources

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