Results 91 to 100 of about 63,766 (174)
Frontiers in Cellular Neuroscience, 2017 Previous studies have demonstrated immunosuppressive and anti-inflammatory effects of nicotine, including in the experimental autoimmune encephalomyelitis (EAE) model in mice of some forms of multiple sclerosis (MS).
Qiang Liu +4 more
doaj +1 more source
Establishing an Ion Pair Interaction in the Homomeric {rho}1 {gamma}-Aminobutyric Acid Type A Receptor That Contributes to the Gating Pathway [PDF]
, 2007 {gamma}-Aminobutyric acid type A (GABAA) receptors are members of the Cys-loop superfamily of ligand-gated ion channels. Upon agonist binding, the receptor undergoes a structural transition from the closed to the open state, but the mechanism of gating ...
Dougherty, Dennis A. +2 more
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Analyzing Nicotine Action Against Amyloid Toxicity by NMR‐Pharmacometabolomics: An Exploratory Study
NMR in Biomedicine, Volume 39, Issue 4, April 2026.Combined metabolomic analysis of the intracellular and extracellular portions of SH‐SY5Y cells revealed that, in the presence of Aβ 1–42, nicotine primarily influences pathways related to neurotransmission, energy metabolism, as well as the biosynthesis and degradation of membrane phospholipids.
Enza Napolitano +5 more
wiley +1 more source
Asian Journal of Surgery, 2007 Alpha bungarotoxin (α-BTX) is a neurotoxin isolated from the venom of Bungarus multicinctus that binds specifically to the β-subunits of nicotinic acetylcholine receptors (nAChR) on myotube membranes.
Junichi Kusafuka +5 more
doaj +1 more source
Sequencing of rabies binding region on nicotinic acteylcholine receptor alpha subunits in four host species [PDF]
, 2013 • Rabies virus is known to bind to nicotinic acetylcholine receptors (nAchR) • The virus is known to bind to alpha 1 subunits nAchR • The virus binding region has been characterized in alpha 1 subunits of these receptors • Little research has been ...
Barnard, Karen
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Evolving resistance patterns in Tetranychus urticae and Bemisia tabaci in Greece
Pest Management Science, Volume 82, Issue 4, Page 3544-3551, April 2026.Greek populations of T. urticae and B. tabaci exhibit evolving multi‐resistance, confirmed by bioassays and molecular markers, highlighting the urgent need for evidence‐based resistance monitoring in IPM. Abstract BACKGROUND Pesticide resistance in agricultural pests remains a major barrier to effective and sustainable crop protection.
Anastasia Kampouraki +8 more
wiley +1 more source
Marine Drugs, 2015 6-Bromohypaphorine (6-BHP) has been isolated from the marine sponges Pachymatisma johnstoni, Aplysina sp., and the tunicate Aplidium conicum, but data on its biological activity were not available.
Igor E. Kasheverov +7 more
doaj +1 more source
Riemann-Liouville Fractional Cosine Functions
, 2015 In this paper, a new notion, named Riemann-Liouville fractional cosine function is presented. It is proved that a Riemann-Liouville $\alpha$-order fractional cosine function is equivalent to Riemann-Liouville $\alpha$-order fractional resolvents ...
Mei, Zhan-Dong, Peng, Ji-Gen
core +1 more source
Evaluation of preclinical antipsychotic models used to support first‐in‐human clinical trials
British Journal of Pharmacology, Volume 183, Issue 7, Page 1364-1389, April 2026.Abstract Schizophrenia is regarded as a complex and heterogeneous psychiatric disorder, characterised by diverse symptoms and comorbidities, which complicate both clinical management and drug development. Current pharmacological treatment, primarily based on dopamine D2 receptor antagonism or partial agonism, which has not markedly progressed since the
Thi Viet Ha Nguyen +2 more
wiley +1 more source
Chronic Nicotine Selectively Enhances α4β2* Nicotinic Acetylcholine Receptors in the Nigrostriatal Dopamine Pathway [PDF]
, 2009 These electrophysiological experiments, in slices and intact animals, study the effects of in vivo chronic exposure to nicotine on functional α4β2* nAChRs in the nigrostriatal dopaminergic (DA) pathway.
Cai, Haijiang +5 more
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