Results 71 to 80 of about 955,520 (208)

Metabolic control of mitophagy

open access: yesEuropean Journal of Clinical Investigation, Volume 54, Issue 4, April 2024.
Abstract Mitochondrial dysfunction is a major hallmark of ageing and related chronic disorders. Controlled removal of damaged mitochondria by the autophagic machinery, a process known as mitophagy, is vital for mitochondrial homeostasis and cell survival.
Andreas Zimmermann   +6 more
wiley   +1 more source

Whole blood NAD and NADP concentrations are not depressed in subjects with clinical pellagra [PDF]

open access: yes, 2007
Population surveys for niacin deficiency are normally based on clinical signs or on biochemical measurements of urinary niacin metabolites. Status may also be determined by measurement of whole blood NAD and NADP concentrations. To compare these methods,
Cheung, E   +5 more
core   +2 more sources

Personalized Porous Gelatin Methacryloyl Sustained‐Release Nicotinamide Protects Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, Volume 11, Issue 12, March 27, 2024.
NAD+ decreases in cochlear after noise trauma, and nicotinamide supplementation boosts NAD+ and prevents neuroexcitatory in cochlear by round window administration. Personalized porous gelatin methacryloyl (PGMA) achieves long term drug release in cochlear, and nicotinamide encapsulated PGMA enhances mitochondria and synapse function, and protects ...
Baoyi Feng   +10 more
wiley   +1 more source

Nicotinamide adenine dinucleotide extends the lifespan of Caenorhabditis elegans mediated by sir-2.1 and daf-16 [PDF]

open access: yes, 2010
It is well understood that sir2 (sirtuin), an NAD-dependent deacetylase, is essential for the extension of lifespan under caloric restriction. However, the mechanism underlying activation of sir2 is unclear.
Hashimoto Teppei   +4 more
core   +1 more source

Outlook of logging perspectives in the Czech Republic for the period 2013-2032

open access: yesJournal of Forest Science, 2014
The aim of the submitted work was to analyze the outlook of logging perspectives in the next two decades (2013-2032) for all forests in the territory of the Czech Republic.
M. Synek, J. Vašíček, M. Zeman
doaj   +1 more source

Characterization of the human omega-oxidation pathway for omega-hydroxy-very-long-chain fatty acids [PDF]

open access: yes, 2008
Very-long-chain fatty acids (VLCFAs) have long been known to be degraded exclusively in peroxisomes via beta-oxidation. A defect in peroxisomal beta-oxidation results in elevated levels of VLCFAs and is associated with the most frequent inherited ...
Dacremont, Georges   +4 more
core   +2 more sources

Psychomotor activities in the context of kinanthropology: Review

open access: yesTělesná Kultura, 2015
BACKGROUND: Any scholar developing a therapeutic method shall be concerned with its historical and theoretical groundings, scientifically verifiedfacts, and information from professional publications.
Běla Hátlová   +2 more
doaj   +1 more source

Ising transition in a one-dimensional quarter-filled electron system with dimerization

open access: yes, 2001
We examine critical properties of the quarter-filled one-dimensional Hubbard model with dimerization and with the onsite and nearest-neighbor Coulomb repulsion U and V.
Bourbonnais   +15 more
core   +1 more source

Research Progress on Mechanism of NAD+ Metabolic Remodeling in Occurrence and Development of Glioblastoma Multiforme

open access: yesZhongliu Fangzhi Yanjiu
Gliomas, especially high-grade gliomas such as glioblastoma multiforme (GBM), are primary malignant tumors of the central nervous system, characterized by high proliferative capacity, invasiveness, and therapeutic resistance.
Jiajia CHE   +6 more
doaj   +1 more source

Identifying and categorizing influencers on Instagram with eye tracker [PDF]

open access: yesSpanish Journal of Marketing-ESIC
Purpose – This paper aims to explore the recognition and success of different ways of branding native advertising in influencer marketing. Design/methodology/approach – The data are evaluated using statistical tests, correlation and cluster analysis ...
Michaela Jánská   +2 more
doaj   +1 more source

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