Results 151 to 160 of about 71,648 (238)

Evidence that feedback inhibition of NAD kinase controls responses to oxidative stress [PDF]

, 2006
Julianne H. Grose, Lisa Joss, Sidney F. Velick, John R. Roth   +3 more
openalex   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Transcriptional Isoforms of NAD⁺ kinase regulate oxidative stress resistance and melanoma metastasis. [PDF]

Redox Biol
Cascio G, Aguirre KN, Church KP, Hughes RO, Nease LA, Delclaux I, Davis HJ, Piskounova E.   +7 more
europepmc   +1 more source

Structure of a NAD kinase fromThermotoga maritimaat 2.3 Å resolution [PDF]

, 2005
Vaheh Oganesyan, Candice Huang, Paul D. Adams, Jaru Jancarik, Hisao Yokota, Rosalind Kim, Sung‐Hou Kim   +6 more
openalex   +1 more source

Establishment and optimization of the two‐step induction system for generating primordial germ cell‐like cells from chicken embryonic stem cells

FEBS Open Bio, EarlyView.
This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li, XianShuai Xu, GuangZheng Liu, XiaoQian Lv, JiuZhou Song, HongYan Sun, YingJie Niu, QiSheng Zuo, Wei Han, BiChun Li, Kai Jin   +10 more
wiley   +1 more source

A group of L-type lectin receptor kinases function redundantly in mediating extracellular NAD(P) signaling in Arabidopsis [PDF]

Qi Li, M. Zhou, Fiona M. Harris, Zhonglin Mou   +3 more
openalex   +1 more source

Molecular cloning and identification ofUTR1of a yeastSaccharomyces cerevisiaeas a gene encoding an NAD kinase [PDF]

, 2001
Shigeyuki Kawai, Sachiko Suzuki, Shigetarou Mori, Kousaku Murata   +3 more
openalex   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Targeting NAD+ salvage pathway induces autophagy in multiple myeloma cells via mTORC1 and extracellular signal-regulated kinase (ERK1/2) inhibition [PDF]

, 2012
Michele Cea, Antonia Cagnetta, Mariateresa Fulciniti, Yu‐Tzu Tai, Teru Hideshima, Dharminder Chauhan, Aldo M. Roccaro, Antonio Sacco, Teresa Calimeri, Francesca Cottini, Jana Jakubı́ková, Sun‐Young Kong, Franco Patrone, Alessio Nencioni, Marco Gobbi, Paul G. Richardson, Nikhil C. Munshi, Kenneth C. Anderson   +17 more
openalex   +1 more source