Results 1 to 10 of about 5,417 (111)

Activity of NAD(P)H-Oxidoreductases in Ovarian Cancer [PDF]

Biomedicines
Reactive oxygen species (ROS) play an important and controversial role in carcinogenesis. Microsomal redox chains containing NADH- and NADPH-dependent oxidoreductases are among the main sites of intracellular ROS synthesis, but their role in the ...
Maria V. Fedorova, Vladimir I. Voznesensky, Elena A. Sosnova, Elena V. Proskurnina   +3 more
doaj   +2 more sources

The two alternative NADH:quinone oxidoreductases from Staphylococcus aureus: two players with different molecular and cellular roles [PDF]

Microbiology Spectrum
Staphylococcus aureus is an opportunistic pathogen that has emerged as a major public health threat due to the increased incidence of its drug resistance. S.
Filipa V. Sena, Filipe M. Sousa, Ana R. Pereira, Teresa Catarino, Eurico J. Cabrita, Mariana G. Pinho, Francisco R. Pinto, Manuela M. Pereira   +7 more
doaj   +2 more sources

Assessing POR and CYB5R1 oxidoreductase-mediated oxidative rupture of PUFA in liposomes

STAR Protocols, 2021
Summary: Lipid peroxidation of polyunsaturated fatty acid (PUFA) phospholipids induces necrotic cell death through compromised cell membrane integrity during ferroptosis.
Bo Yan, Youwei Ai, Zhiyuan Zhang, Xiaodong Wang   +3 more
doaj   +1 more source

The oxidoreductases POR and CYB5R1 catalyze lipid peroxidation to execute ferroptosis

Molecular & Cellular Oncology, 2021
Our recent study showed that two oxidoreductases – NADPH-cytochrome P450 reductase (POR) and NADH-cytochrome b5 reductase (CYB5R1) – transfer electrons to oxygen to generate hydrogen peroxide (H2O2).
Youwei Ai, Bo Yan, Xiaodong Wang
doaj   +1 more source

Copper oxide-based cathode for direct NADPH regeneration

Scientific Reports, 2021
Nearly a fourth of all enzymatic activities is attributable to oxidoreductases, and the redox reactions supported by this vast catalytic repertoire sustain cellular metabolism.
J. T. Kadowaki, T. H. Jones, A. Sengupta, V. Gopalan, V. V. Subramaniam   +4 more
doaj   +1 more source

Intensifying Electron Utilization by Surface-Anchored Rh Complex for Enhanced Nicotinamide Cofactor Regeneration and Photoenzymatic CO2 Reduction

Research, 2021
Solar-driven photocatalytic regeneration of cofactors, including reduced nicotinamide adenine dinucleotide (NADH), reduced nicotinamide adenine dinucleotide phosphate (NADPH), and reduced flavin adenine dinucleotide (FADH2), could ensure the sustainable ...
Yuqing Cheng, Jiafu Shi, Yizhou Wu, Xueying Wang, Yiying Sun, Ziyi Cai, Yu Chen, Zhongyi Jiang   +7 more
doaj   +1 more source

Characterization of NADH Oxidase/NADPH Polysulfide Oxidoreductase and Its Unexpected Participation in Oxygen Sensitivity in an Anaerobic Hyperthermophilic Archaeon [PDF]

Journal of Bacteriology, 2010
ABSTRACT Many genomes of anaerobic hyperthermophiles encode multiple homologs of NAD(P)H oxidase that are thought to function in response to oxidative stress. We investigated one of the seven NAD(P)H oxidase homologs (TK1481) in the sulfur-reducing hyperthermophilic archaeon Thermococcus kodakarensis ...
Satoshi Nakamura, HIROKI KOBORI, MASAYUKI OGINO, IZUMI ORITA, TADAYUKI IMANAKA, TOSHIAKI FUKUI   +5 more
openaire   +2 more sources

Identification of oxidoreductases from the petroleum Bacillus safensis strain

Biotechnology Reports, 2015
A gram-positive bacterium, denominated CFA-06, was isolated from Brazilian petroleum in the Campos Basin and is responsible for the degradation of aromatic compounds and petroleum aromatic fractions.
Francine S.A. da Fonseca, Célio F.F. Angolini, Marco A. Zezzi Arruda, Cícero A.L. Junior, Clelton A. Santos, Antonio M. Saraiva, Eduardo Pilau, Anete P. Souza, Prianda R. Laborda, Patrícia F.L. de Oliveira, Valéria M. de Oliveira, Francisco de Assis M. Reis, Anita J. Marsaioli   +12 more
doaj   +1 more source

The Ability of New Sugar-Modified Derivatives of Antitumor Anthracycline, Daunorubicin, to Stimulate NAD(P)H Oxidation in Different Cellular Oxidoreductase Systems: NADH Dehydrogenase, NADPH Cytochrome P450 Reductase, and Xanthine Oxidase

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics, 2004
Numerous data indicate that cellular oxidoreductases may be responsible for the cardiotoxic effects of antitumor anthracycline drugs as a consequence of the mediation by these agents of one-electron transfer from reduced nucleotides to atmospheric oxygen.
Jolanta, Pawłowska, Waldemar, Priebe, Mark J I, Paine, C Roland, Wolf, Edward, Borowski, Jolanta, Tarasiuk   +5 more
openaire   +2 more sources

Reduction of the plastoquinone pool by exogenous NADH and NADPH in higher plant chloroplasts Characterization of a NAD(P)H–plastoquinone oxidoreductase activity

Biochimica et Biophysica Acta (BBA) - Bioenergetics
AbstractChlorophyll fluorescence measurements were performed on osmotically lysed potato chloroplasts in order to characterize the reactions involved in the dark reduction of photosynthetic inter-system chain electron carriers. Addition of NADH or NADPH to lysed chloroplasts increased the chlorophyll fluorescence level measured in the presence of a non-
Corneille, Sylvie, Cournac, Laurent, Guedeney, Geneviève, Havaux, Michel, Peltier, Gilles   +4 more
openaire   +3 more sources