Results 31 to 40 of about 5,514 (117)

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 24, 25 June 2026.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta   +3 more
wiley   +1 more source

Engineering of CoA‐Acylating Butyraldehyde Dehydrogenase for Enhanced 1,3‐Butanediol Production in Escherichia coli

open access: yesBiotechnology and Bioengineering, Volume 123, Issue 6, Page 1605-1614, June 2026.
ABSTRACT Microbial production of 1,3‐butanediol (1,3‐BDO) offers a renewable route to this versatile C4 chemical. However, the low performance of CoA‐acylating butyraldehyde dehydrogenase (Bld), which contains a catalytic cysteine, limits efficient production in recombinant Escherichia coli (E. coli).
Seunghyun Cho   +5 more
wiley   +1 more source

The Development and Characterization of a Panel of Amine Dehydrogenases (AmDHs) and Amino Acid Dehydrogenases (AADHs)

open access: yesChemCatChem, Volume 18, Issue 11, 15 June 2026.
The CoE‐AmDH panel enables sustainable access to chiral amines using diverse amine (AmDH) and amino acid dehydrogenases (AADH). Utilizing formate (FDH) or glucose dehydrogenase (GDH) for cofactor regeneration, this study establishes a robust screening platform for mild reductive aminations.
R. Tilly Bradshaw Allen   +2 more
wiley   +1 more source

Genomic and Transcriptomic Insights Into Salinity Tolerance in Dry Pea

open access: yesLegume Science, Volume 8, Issue 2, June 2026.
ABSTRACT Salinity is a major crop production constraint in dry pea (Pisum sativum L.), making the development of salt‐tolerant varieties essential to improve crop productivity and land‐use efficiency. The genetic mechanisms of salt tolerance in dry pea are largely unknown, and research on salt‐tolerant genes is limited.
Shailesh Raj Acharya   +11 more
wiley   +1 more source

Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang   +7 more
wiley   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang   +14 more
wiley   +1 more source

Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesPortal Hypertension &Cirrhosis, Volume 5, Issue 2, Page 189-206, June 2026.
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang   +5 more
wiley   +1 more source

bZIP Transcription Factor PobZIP8 Positively Mediates Heat Stress Tolerance and Negatively Regulates the Growth and Development of Pleurotus ostreatus

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
PobZIP8 from Pleurotus ostreatus enhances heat stress tolerance while negatively regulating fruiting body development, providing a key target for genetic improvement of edible fungi. ABSTRACT Pleurotus ostreatus is a globally cultivated edible and medicinal fungus, but its growth and yield are significantly affected by heat stress during cultivation ...
Yi Zhou   +7 more
wiley   +1 more source

Microbial Electrosynthesis Reshapes Energy Metabolism and Physiology in Clostridium ljungdahlii

open access: yesMicrobial Biotechnology, Volume 19, Issue 6, June 2026.
Microbial electrosynthesis drives Clostridium ljungdahlii into a distinct stress‐associated physiological state, different from gas fermentation. Comparative multi‐omics and electron microscopy reveal physiological constraints that help explain the poor performance of MES.
Sara Al Sbei   +8 more
wiley   +1 more source

The miR171a‐TaSCL6‐1 Module Acts Downstream of miR164‐Targeted TaNAC21/22 to Regulate Leaf Rust Resistance in Wheat

open access: yesPlant Biotechnology Journal, Volume 24, Issue 6, Page 3723-3738, June 2026.
ABSTRACT Wheat leaf rust, caused by Puccinia triticina, poses a significant threat to global wheat production. MicroRNAs (miRNAs) are critical regulators of plant growth, development and stress responses; however, their role in wheat resistance to leaf rust remains poorly understood.
Mengjiao Guo   +12 more
wiley   +1 more source

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