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Aripiprazole increases NADPH level in PC12 cells: the role of NADPH oxidase
Journal of Neural Transmission, 2013In aripiprazole-treated PC12 cells, we previously showed that the mitochondrial membrane potential (Δψm) was rather increased in spite of lowered cytochrome c oxidase activity. To address these inconsistent results, we focused the NADPH generation by glucose-6-phosphate dehydrogenase (G6PD), a rate-limiting enzyme of the pentose phosphate pathway (PPP),
Hiroshi, Nagasaki +10 more
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Phospholipases and activation of the NADPH oxidase
European Journal of Haematology, 1993Abstract: The signal transductional mechanisms regulating the activation of NADPH oxidase, the respiratory burst enzyme in phagocytic cells, are not completely understood. Receptors for most physiologic stimuli trigger the activation of various phospholipases, including phospholipases A2, C, and D.
L C, McPhail +3 more
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Compartmentation of NADPH in rat liver
Archives of Biochemistry and Biophysics, 1977Abstract Rat liver slices were incubated with specifically 3 H-labeled glucoses and [2- 3 H]sorbitol, and the incorporations of 3 H into fatty acids and cholesterol were determined. Incorporation of 3 H from [1- 3 H]glucose relative to that from [3- 3 H]glucose via NADPH formed in the pentose cycle was similar into fatty acids and cholesterol ...
M S, Kong, B R, Landau
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A burst of plant NADPH oxidases
Trends in Plant Science, 2012Reactive oxygen species (ROS) are highly reactive molecules able to damage cellular components but they also act as cell signalling elements. ROS are produced by many different enzymatic systems. Plant NADPH oxidases, also known as respiratory burst oxidase homologues (RBOHs), are the most thoroughly studied enzymatic ROS-generating systems and our ...
Marino, Daniel +3 more
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Cyanobacterial NADPH dehydrogenase complexes
Photosynthesis Research, 2007Cyanobacteria possess functionally distinct multiple NADPH dehydrogenase (NDH-1) complexes that are essential to CO(2) uptake, photosystem-1 cyclic electron transport and respiration. The unique nature of cyanobacterial NDH-1 complexes is the presence of subunits involved in CO(2) uptake.
Teruo, Ogawa, Hualing, Mi
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Assembly of the phagocyte NADPH oxidase
Histochemistry and Cell Biology, 2004Stimulated phagocytes undergo a burst in respiration whereby molecular oxygen is converted to superoxide anion through the action of an NADPH-dependent oxidase. The multicomponent phagocyte oxidase is unassembled and inactive in resting cells but assembles at the plasma or phagosomal membrane upon phagocyte activation.
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Lactate and glutamine support NADPH generation in cancer cells under glucose deprived conditions
Redox Biology, 2021Minfeng Ying, Limeng Cai, Xun Hu
exaly