Differential effects of lipid composition on the thermal and functional properties of membrane associated CYP2J2. [PDF]
Das R, Mastrion HM, Vassar HB, Das A.
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Thermodynamic metabolic modeling of growth and bioproduction potential of the acetogen <i>Acetobacterium woodii</i> with and without redox cofactor swaps. [PDF]
Bauer J, von Kamp A, Pflügl S, Klamt S.
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Metabolic plasticity and optimal redox homeostasis are essential for efficient metastatic colonization. [PDF]
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Insights into Neutrophil Dysfunction in Inherited Metabolic Disorders. [PDF]
Wolf A +8 more
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Structural basis of ligand selectivity in FAD/NAD(P)H-dependent dehydrogenases: insights from trypanothione reductase and type II NADH dehydrogenase. [PDF]
Perrone GCM +15 more
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ADH4 deficiency activates the NRF2-CSF1 axis by increased lipid peroxidation in hepatocellular carcinoma. [PDF]
Yan P +8 more
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Fast Motions in 5 Alpha Reductase and Its Impact on Enzyme Kinetics. [PDF]
Roy RK, Antoniou D, Schwartz SD.
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A Unique NCF2 Mutation in Chronic Granulomatous Disease: Clinical and Computational Insights into NADPH Oxidase Dysfunction. [PDF]
Yu H, Hu R, He J, Tian X, Zhang T.
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Superoxide is instrumental in the killing of microorganisms by phagocytic cells. It is generated by the NADPH oxidase system, a membrane-bound electron transport complex which pumps electrons from NADPH in the cytoplasm across the wall of the phagocytic vacuole to molecular oxygen.
K P, Shatwell, A W, Segal
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The binding of the substrate NADPH as well as a number of fragments and derivatives of NADPH to glutathione reductase from human erythrocytes has been investigated by using X-ray crystallography. Crystals of the enzyme were soaked with the compounds of interest, and then the diffraction intensities were collected out to a resolution of 3 A.
Pai, E., Karplus, P., Schulz, G.
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