Results 181 to 190 of about 143,942 (291)

The prevalence and predictors of non-alcoholic fatty liver disease in Chinese patients with inflammatory bowel disease: a multicenter retrospective study. [PDF]

Sci Rep
Shen Y, Liang F, Li Q, Zhang Y, Fu C, Sun X, Ge H, Fan W, Xie Y, Peng C, Wang L, Wen B, Huang W, Zhang L, Zhang X.   +14 more
europepmc   +1 more source

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

The association between non-alcoholic fatty liver disease with blood selenium level based on the NHANES 2017-2020. [PDF]

Clin Exp Med
Chen J, Jiang H, Fang X.
europepmc   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

The FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou, Christina Arseni, Kreon Koukoulas, Martina Samiotaki, George Panayotou, George Simos, Ilias Mylonis   +6 more
wiley   +1 more source

Analysis of the incidence and risk factors of colorectal polyps in patients with chronic hepatitis B complicated by non - alcoholic fatty liver disease. [PDF]

BMC Gastroenterol
Ma L, Zheng WW, Zhang Y, Wei W, Zhao Y, Zhang XJ, Pan PY, Li JZ, Li ZH, Wang QP, Wang CY.   +10 more
europepmc   +1 more source

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

The fibrosis-4 index for advanced liver fibrosis in NAFLD with T2DM: Half a loaf is better than no bread [PDF]

Clinical and Molecular Hepatology
Zeyu Wang, Dong Wan, Meidong Xu, Yong Jiang   +3 more
doaj   +1 more source

The Importance of Serum Perilipin-2 Level as an Early Indicator of Inflammation in Non-Alcoholic Fatty Liver Disease. [PDF]

Diagnostics (Basel)
Alpaydin OV, Duran EN, Hur Alpaydin A, Ekinci I, Dumur S, Uzun H, Akarsu M, Yalcinkaya I, Tabak O.   +8 more
europepmc   +1 more source

Metabolic Health Phenotypes Among Middle‐ to Older‐Aged Adults Living With and Without Obesity: Relationships With Hepatic Health Indicators

Hepatology Research, EarlyView.
We examined liver health indicators among obese and nonobese metabolic health phenotypes. In fully adjusted models, higher fatty liver index (FLI) scores and liver enzyme concentrations of gamma‐glutamyl transferase (GGT) and alanine aminotransferase (ALT) were associated with lower likelihood of metabolically healthy obese (MHO) and nonobese (MHNO ...
Grainne Dolan, Seán R. Millar, Ivan J. Perry, Catherine M. Phillips   +3 more
wiley   +1 more source

Targeting the intestinal barrier with traditional Chinese medicine for non-alcoholic fatty liver disease: mechanistic insights and therapeutic perspectives. [PDF]

Chin Med
Cheng X, Li S, Huang C, Yang Y, Liu R, Cao S, Luo L, Lu B.   +7 more
europepmc   +1 more source