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Immunotherapy for NAFLD and NAFLD-related hepatocellular carcinoma
Frontiers in Endocrinology, 2023 The progression of non-alcoholic fatty liver disease (NAFLD), the most common liver disease, leads to non-alcoholic steatohepatitis and hepatocellular carcinoma. Despite the increasing incidence and prevalence of NAFLD, its therapeutic and preventive strategies to lower the disease burden is limited.
Seogsong Jeong +3 more
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JHEP Reports, 2021 Non-alcoholic fatty liver disease (NAFLD) is a growing cause of chronic liver disease worldwide. It is characterised by steatosis, liver inflammation, hepatocellular injury and progressive fibrosis. Several preclinical models (dietary and genetic animal models) of NAFLD have deepened our understanding of its aetiology and pathophysiology.
Parlati, Lucia +3 more
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Current management of NAFLD [PDF]
Medicine and Pharmacy Reports, 2016 Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in Western countries. It affects about 1 billion individuals worldwide. While people with simple steatosis have no higher risk of death than the general population, people with non-alcoholic steatohepatitis are at increased risk of death compared to general ...
MUNTEANU, MIHAI ALEXANDRU +2 more
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International Journal of Molecular Sciences, 2023 The aim of the second edition of our Special Issue, entitled “Nonalcoholic Fatty Liver Disease/Metabolic Associated Fatty Liver Disease: New Insights 2 [...]
Alessandro Mantovani, Andrea Dalbeni
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Nonalcoholic fatty liver disease in Brazil. Clinical and histological profile
Annals of Hepatology, 2011 Background. The epidemiology and clinical characteristics of nonalcoholic fatty liver disease (NAFLD) in South America are not well known. Brazil is a largest country in this part of the world and the present study aimed to contribute with this ...
Helma P. Cotrim +15 more
doaj +1 more source
Evaluation of polygenic determinants of non-alcoholic fatty liver disease (NAFLD) by a candidate genes resequencing strategy [PDF]
, 2018 NAFLD is a polygenic condition but the individual and cumulative contribution of identified genes remains to be established. To get additional insight into the genetic architecture of NAFLD, GWAS-identified GCKR, PPP1R3B, NCAN, LYPLAL1 and TM6SF2 genes ...
Angelico F +16 more
core +1 more source
Natural History of NAFLD [PDF]
Journal of Clinical Medicine, 2021 The epidemiology and the current burden of chronic liver disease are changing globally, with non-alcoholic fatty liver disease (NAFLD) becoming the most frequent cause of liver disease in close relationship with the global epidemics of obesity, type 2 diabetes and metabolic syndrome.
Pais, Raluca, Maurel, Thomas
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European Thyroid Journal, 2023 Thyroid hormones play an essential role in regulating whole-body homeostasis. Deiodinases are known to convert thyroid hormone from the prohormone thyroxine (T4) to the bioactive hormone tri-iodothyronine (T3) and convert both T4 and T3 toward their ...
Eveline Bruinstroop +2 more
doaj +1 more source
Two-hour postload glycemia is associated to an increased risk of NAFLD in healthy subjects with family history of type 2 diabetes: a case control study [PDF]
, 2016 Nonalcoholic fatty liver disease (NAFLD) includes steatosis and nonalcoholic steatohepatitis (NASH), which can be complicated by cirrhosis and hepatocellular carcinoma [1].
CARNOVALE, ANNA +7 more
core +1 more source
The effect of low volume sprint interval training in patients with non-alcoholic fatty liver disease [PDF]
, 2017 Objectives: Exercise is an important part of disease management in patients with non-alcoholic fatty liver disease (NAFLD), but adherence to current exercise recommendations is poor.
Babraj, John A. +3 more
core +5 more sources