Results 11 to 20 of about 96,262 (339)
Archiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023 Based on a simplified version of the morphinan scaffold, 3‐[3‐(phenalkylamino)cyclohexyl]phenol analogues were designed, synthesized and evaluated for their µ‐opioid receptor (MOR) antagonist activity in vitro and in silico. Docking studies indicate a peculiar combination of C‐1 stereochemistry and N‐substitutions as feasibly essential for MOR‐ligand ...
Graziella Tocco +8 more
wiley +1 more source
Practical implications of naloxone knowledge among suburban people who use opioids
Harm Reduction Journal, 2021 Background Naloxone distribution programs have been a cornerstone of the public health response to the overdose crisis in the USA. Yet people who use opioids (PWUO) continue to face a number of barriers accessing naloxone, including not knowing where it ...
Kristin E. Schneider +6 more
doaj +1 more source
Neuroimaging for differential diagnosis of transient neurological attacks
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley +1 more source
Pharmacy, 2020 Pharmacists represent a key group of healthcare professionals that can increase awareness and destigmatize naloxone use. The objective of this study was to investigate pharmacy student perceptions of the use, dispensing, and stigma surrounding naloxone ...
Alina Cernasev +4 more
doaj +1 more source
PLoS ONE, 2021 IntroductionTake-Home Naloxone programs have been introduced across North America in response to rising opioid overdose deaths. There is currently limited real-world data on bystander naloxone administration, overdose outcomes, and evidence related to ...
Amina Moustaqim-Barrette +6 more
doaj +2 more sources
Patient perspectives on naloxone receipt in the emergency department: a qualitative exploration
Harm Reduction Journal, 2022 Background Emergency departments (EDs) are important venues for the distribution of naloxone to patients at high risk of opioid overdose, but less is known about patient perceptions on naloxone or best practices for patient education and communication ...
Margaret Lowenstein +5 more
doaj +1 more source
Harm reduction behaviors are associated with carrying naloxone among patients on methadone treatment
Harm Reduction Journal, 2023 Background Despite the widespread availability of naloxone, US opioid overdose rates continue to rise. The “Cascade of Care” (CoC) is a public health approach that identifies steps in achieving specific outcomes and has been used to identify gaps in ...
Zofia Kozak +11 more
doaj +1 more source
Pharmacy, 2021 A recent report found that the number of opioid-related deaths in Ontario in the first 15 weeks of the COVID-19 pandemic was 38.2% higher than in the 15 weeks before the pandemic.
George Daskalakis +3 more
doaj +1 more source
Harm Reduction Journal, 2022 Background Expanding availability to naloxone is a core harm reduction strategy in efforts to address the opioid epidemic. In the US, state-level legislation is a prominent mechanism to expand naloxone availability through various venues, such as ...
Sean Grant, Rosanna Smart
doaj +1 more source