Results 11 to 20 of about 75,178 (323)
Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér+6 more
core +5 more sources
Nobody Wants to Be Narcan’d: A Pilot Qualitative Analysis of Drug Users’ Perspectives on Naloxone
Introduction: Bystander naloxone distribution is an important component of public health initiatives to decrease opioid-related deaths. While there is evidence supporting naloxone distribution programs, the effects of increasing naloxone availability on ...
Jeffrey T. Lai+6 more
doaj +1 more source
Predicting pharmacy naloxone stocking and dispensing following a statewide standing order, Indiana 2016 [PDF]
BACKGROUND: While naloxone, the overdose reversal medication, has been available for decades, factors associated with its availability through pharmacies remain unclear.
Agley, J.D.+8 more
core +1 more source
Background Expanding availability to naloxone is a core harm reduction strategy in efforts to address the opioid epidemic. In the US, state-level legislation is a prominent mechanism to expand naloxone availability through various venues, such as ...
Sean Grant, Rosanna Smart
doaj +1 more source
Summary: Background: The US overdose crisis is driven by fentanyl, heroin, and prescription opioids. One evidence-based policy response has been to broaden naloxone distribution, but how much naloxone a community would need to reduce the incidence of ...
Michael A Irvine, PhD+10 more
doaj +1 more source
PLACENTAL TRANSFER OF NALOXONE [PDF]
Maternal and umbilical venous serum naloxone concentrations were measured after the i.v. (30 mothers) or i.m. (seven mothers) injection of naloxone 400 micrograms. Following i.v. naloxone there was rapid transfer to the fetus and therapeutic plasma concentrations could be expected in 1 or 2 min. However, following i.m.
B.M. Hibbard, D. Davies, M. Rosen
openaire +4 more sources
Homeless drug users' awareness and risk perception of peer "Take Home Naloxone" use – a qualitative study [PDF]
BACKGROUND Peer use of take home naloxone has the potential to reduce drug related deaths. There appears to be a paucity of research amongst homeless drug users on the topic.
A Edwards+27 more
core +3 more sources
The rate of opioid misuse and overdose continues to increase in rural areas of the U.S. In response, access to naloxone hydrochloride (“naloxone”), an opioid antagonist used to reverse opioid overdose, has increased among both first responders and ...
Tess M. Kilwein+3 more
doaj +1 more source
Background: Opioid overdoses continue to be one of the most urgent public health priorities. In 2020, reported overdose deaths in the United States reached a high of over 93,000 cases. As the COVID-19 pandemic and opioid crisis continues to be addressed,
Jennifer Courtney+6 more
doaj +1 more source
Prehospital naloxone administration – what influences choice of dose and route of administration?
Background Amidst the ongoing opioid crisis there are debates regarding the optimal route of administration and dosages of naloxone. This applies both for lay people administration and emergency medical services, and in the development of new naloxone ...
Ida Tylleskar+6 more
doaj +1 more source