Results 61 to 70 of about 96,262 (339)
Harm Reduction Journal, 2023 Background Naloxone is a medication that can quickly reverse an opioid overdose. Syringe service programs (SSPs) are community-based prevention programs that provide a range of evidence-based interventions in the USA, including naloxone distribution ...
Barrot H. Lambdin +7 more
doaj +1 more source
Drugs in Context, 2021 Background: Older adults (≥65 years) have seen significant increases in opioid overdose deaths. Diversion of older adults’ opioid medication is also a contributor to opioid misuse.
Brianna M McQuade +4 more
doaj +1 more source
Messaging to Increase Public Support for Naloxone Distribution Policies in the United States: Results from a Randomized Survey Experiment. [PDF]
PLoS ONE, 2015 Barriers to public support for naloxone distribution include lack of knowledge, concerns about potential unintended consequences, and lack of sympathy for people at risk of overdose.A randomized survey experiment was conducted with a nationally ...
Marcus A Bachhuber +4 more
doaj +1 more source
Towards Better Opioid Antagonists Using Deep Reinforcement Learning [PDF]
arXiv, 2020 Naloxone, an opioid antagonist, has been widely used to save lives from opioid overdose, a leading cause for death in the opioid epidemic. However, naloxone has short brain retention ability, which limits its therapeutic efficacy. Developing better opioid antagonists is critical in combating the opioid epidemic.Instead of exhaustively searching in a ...
arxiv
An opioid-like system regulating feeding behavior in C. elegans [PDF]
, 2015 Neuropeptides are essential for the regulation of appetite. Here we show that neuropeptides could regulate feeding in mutants that lack neurotransmission from the motor neurons that stimulate feeding muscles. We identified nlp-24 by an RNAi screen of 115
Artyukhin, Alexander B. +3 more
core +2 more sources
Drugs, 2019 Naloxone is a well-established essential medicine for the treatment of life-threatening heroin/opioid overdose in emergency medicine. Over two decades, the concept of ‘take-home naloxone’ has evolved, comprising pre-provision of an emergency supply to ...
J. Strang +6 more
semanticscholar +1 more source
JAMA Network Open, 2020 Key Points Question Is there a benefit associated with take-home naloxone for overdose reversals supplied to patients who are receiving treatment for opioid use disorder?
Joanna G. Katzman +7 more
semanticscholar +1 more source
Naloxone Administration Route in Opioid Overdose: A Review of Vermont EMS Data [PDF]
, 2017 Objective: Emergency Medical System (EMS) personnel administer the direct opioid antagonist naloxone in cases of opioid overdose via intramuscular (IM), intravenous (IV), subcutaneous (SQ), intraosseous (IO), or intranasal (IN) routes. Some early studies
LaMonda, Chris, MPH +4 more
core +1 more source
Naloxone dosing in the era of ultra-potent opioid overdoses: a systematic review.
CJEM, 2020 OBJECTIVES Evaluate the relationship between naloxone dose (initial and cumulative) and opioid toxicity reversal and adverse events in undifferentiated and presumed fentanyl/ultra-potent opioid overdoses.
J. Moe +10 more
semanticscholar +1 more source
Effects of pharmacist-driven protocol on naloxone prescribing rates in two primary care clinics
Preventive Medicine Reports, 2023 The Centers for Disease Control and Prevention (CDC) Guidelines for Prescribing Opioids for Chronic Pain recommend co-prescribing naloxone as a harm reduction strategy when there is an increased risk of opioid overdose.
Ashley Daffron +3 more
doaj