Results 61 to 70 of about 48,575 (332)
Orthoptic status before and immediately after heroin detoxification [PDF]
, 2004 Aim: To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. Method: A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification ...
Beaini, A.Y. +3 more
core +2 more sources
Obesity, EarlyView.Abstract Objective The objective of this study was to characterize changes in body weight and glycated hemoglobin (in those with prediabetes at baseline) through 12 months by obesity pharmacotherapy discontinuation status. Methods This retrospective cohort study used electronic health record data from a large health system in Ohio and Florida to ...
Hamlet Gasoyan +8 more
wiley +1 more source
Neurobiology of Disease, 2009 The opioid antagonist naltrexone is the standard pharmacotherapy for alcoholism, although compliance is often low. The mechanism by which naltrexone reduces drinking is yet unclear.
Jennifer M. Mitchell +4 more
doaj
The Journal of Pathology, EarlyView.Abstract Post‐COVID‐19 condition (PCC), also known as long COVID, is a complex multiple organ system condition that can develop and persist for months after acute COVID‐19. PCC encompasses a wide range of symptoms, resulting in heterogeneous clinical manifestations. These manifestations likely arise from diverse underlying pathophysiological mechanisms,
Larissa E Vlaming‐van Eijk +5 more
wiley +1 more source
Chronic opioid pretreatment potentiates the sensitization of fear learning by trauma. [PDF]
, 2020 Despite the large comorbidity between PTSD and opioid use disorders, as well as the common treatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to subsequently modify PTSD-related behavior has not been well ...
Evans, Christopher J +6 more
core +1 more source
Tissue compatibility of poly(hydroxypropylglutamate)-prazosin conjugates [PDF]
, 1992 Biocompatibility of an injectable biodegradable drug delivery system for prazosin was investigated in Sprague-Dawley rats by histological studies after subcutaneous injection ofpoly(hydroxypropyl glutamate)-prazosin (PHPG-prazosin) conjugate particles ...
Anderson, James M. +4 more
core +2 more sources
Transforming Niclosamide through Nanotechnology: A Promising Approach for Long COVID Management
Small, EarlyView.This review highlights the transformation of niclosamide, a repurposed drug, through molecular science strategies to overcome its pharmacokinetic limitations. Emphasizing novel nanohybrid technologies and delivery platforms, the article explores their therapeutic potential in targeting the complex pathophysiology of long COVID, paving the way for ...
Sanoj Rejinold N +3 more
wiley +1 more source
Alcoholism: Clinical and Experimental Research, 2019 Background Precision medicine aims to identify those patients who will benefit the most from specific treatments. Recent work found large effects of naltrexone among “reward drinkers,” defined as individuals who drink primarily for the rewarding effects ...
K. Witkiewitz +3 more
semanticscholar +1 more source
Naltrexone Protects Against Lipopolysaccharide/D-Galactosamine–Induced Hepatitis in Mice
Journal of Pharmacological Sciences, 2008 Naltrexone, an opioid receptor antagonist, has been claimed to have anti-inflammatory and immunomodulatory effects both in vitro and in vivo.
Chien-Chuan Wang +5 more
doaj
Harm Reduction Journal, 2012 Background Respiratory depression, a potentially fatal side-effect of opioid-overdose, may be reversed by timely administration of an opioid antagonist, such as naloxone or naltrexone.
Goli Veeraindar +5 more
doaj +1 more source