Results 21 to 30 of about 15,085 (211)
Cell Communication and Signaling, 2020 Background The role and mechanism of the nicotinamide adenine dinucleotide (NAD+) salvage pathway in cancer cell proliferation is poorly understood.
Chenyang Ye +8 more
doaj +1 more source
The influence of age on the responses of serum visfatin and insulin resistance to a single session of endurance exercise [PDF]
فیزیولوژی ورزش و فعالیت بدنی, 2013 Purpose: The purpose of this study was to investigate the effects of age on the responses of serum visfatin and insulin resistance index to a single session of endurance exercise.
هیوا رحمانی +3 more
doaj +1 more source
Resveratrol differentially regulates NAMPT and SIRT1 in hepatocarcinoma cells and primary human hepatocytes [PDF]
, 2014 Resveratrol is reported to possess chemotherapeutic properties in several cancers. In this study, we wanted to investigate the molecular mechanisms of resveratrol-induced cell cycle arrest and apoptosis as well as the impact of resveratrol on NAMPT and ...
Antje Garten +7 more
core +7 more sources
Exposure to nanographene oxide induces gene expression dysregulation in normal human astrocytes
Endocrine Regulations, 2022 Objective. Nanographene oxide, an oxidation derivative of graphene, is considered to be one of the nanomaterials attractive for biomedical applications, although this nanomaterial is toxic.
Rudnytska Olha V. +8 more
doaj +1 more source
Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control [PDF]
, 2008 The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by decoding changes in nocturnal melatonin secretion.
Alison Downing +83 more
core +2 more sources
Nampt: linking NAD biology, metabolism and cancer [PDF]
Trends in Endocrinology & Metabolism, 2009 Nicotinamide phosphoribosyltransferase (Nampt) converts nicotinamide to nicotinamide mononucleotide (NMN), a key nicotinamide adenine dinucleotide (NAD) intermediate. Previously identified as a cytokine pre-B-cell colony-enhancing factor and controversially claimed as an insulin-mimetic hormone visfatin, Nampt has recently drawn much attention in ...
Antje, Garten +4 more
openaire +2 more sources
Regulation of Regenerative Periodontal Healing by NAMPT [PDF]
Mediators of Inflammation, 2013 Periodontitis is an inflammatory disease characterized by destruction of the tooth-supporting tissues. Obese individuals have an increased risk of periodontitis, and elevated circulating levels of nicotinamide phosphoribosyltransferase (NAMPT) may be a pathomechanistic link between both diseases. Recently, increased levels of NAMPT have also been found
Marjan Nokhbehsaim +4 more
openaire +4 more sources
Pyrroloquinoline quinone increases the expression and activity of Sirt1 and -3 genes in HepG2 cells. [PDF]
, 2015 Sirtuin (Sirt) 1 and Sirt 3 are nicotinamide adenine dinucleotide ((+))-dependent protein deacetylases that are important to a number of mitochondrial-related functions; thus, identification of sirtuin activators is important. Herein, we hypothesize that
Arguelles, Andrix +6 more
core +1 more source
NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.
PLoS ONE, 2019 Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in mammalian nicotinamide adenine dinucleotide (NAD)+ biosynthesis. Through its NAD+-biosynthetic activity, NAMPT influences the activity of NAD+-dependent enzymes, such as sirtuins.
Xiwen Xiong +9 more
doaj +1 more source
Cell Reports, 2019 Summary: Nicotinamide adenine dinucleotide (NAD+) metabolism plays a critical role in kidneys. We previously reported that decreased secretion of a NAD+ precursor, nicotinamide mononucleotide (NMN), from proximal tubules (PTs) can trigger diabetic ...
Hirokazu Muraoka +9 more
doaj +1 more source