Results 51 to 60 of about 16,217 (195)
Tiny But Mighty - Nanobodies Tafesse
, 2023 In this video, from Digital World Biology, Dr. Tavasa discusses research on tuberculosis (TB) and the development of nanobodies as potential diagnostic and therapeutic tools. During the video, Dr.
Tafesse, Fikadu G.
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Generation and characterization of Nanomedicines stabilizing alpha-1 antitrypsin
, 2022 reservedSviluppo e caratterizzazione di nanobodies per malattie infiammatorie polmonariGeneration and characterization of nanobodies against lung ...
LESTANI, SARA
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Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies
2’,3’-cyclic nucleotide 3’-phosphodiesterase (CNPase) is an abundant constituent of central nervous system non-compact myelin, frequently used as a marker antigen for myelinating cells.
Körner, Henrike +10 more
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Structural Basis of Nanobodies Targeting the Prototype Norovirus
, 2019 Human norovirus infections are a major disease burden. In this study, we analyzed three new norovirus-specific Nanobodies that interacted with the prototype human norovirus (i.e., GI.1). We showed that the Nanobodies bound on the side (Nano-7 and Nano-62)
Koromyslova, A +10 more
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Applications of Nanobodies in Mycotoxin Detection
, 2022 Mycotoxins, as secondary metabolites produced by fungi, are a common threat to food safety and are hazardous to human and livestock health. Mycotoxin contamination of agricultural products causes significant economic losses worldwide.
Shaowen WU +3 more
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Nanobodies detecting and modulating GPCRs outside in and inside out [PDF]
, 2019 G protein-coupled receptors (GPCRs), belonging to the largest class of membrane proteins, play a prominent role in many (patho)physiological processes and are, therefore, important drug targets.
Smit, Martine J. +3 more
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Table_1_Applications of nanobodies in brain diseases.docx
, 2022 Nanobodies are antibody fragments derived from camelids, naturally endowed with properties like low molecular weight, high affinity and low immunogenicity, which contribute to their effective use as research tools, but also as diagnostic and therapeutic ...
Fang Zheng (54278) +6 more
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Nanobodies and Nanobody-Based Human Heavy Chain Antibodies As Antitumor Therapeutics [PDF]
Frontiers in Immunology, 2017 Monoclonal antibodies have revolutionized cancer therapy. However, delivery to tumor cells in vivo is hampered by the large size (150 kDa) of conventional antibodies. The minimal target recognition module of a conventional antibody is composed of two non-covalently associated variable domains (VH and VL).
Peter Bannas +2 more
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Toxins, 2014 Nanobodies are the smallest natural fragments with useful properties such as high affinity, distinct paratope and high stability, which make them an ideal tool for detecting target antigens.
Min Li +4 more
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NANOBODIES(®): A Review of Generation, Diagnostics and Therapeutics
, 2023 NANOBODY(®) (a registered trademark of Ablynx N.V) molecules (Nbs), also referred to as single domain-based VHHs, are antibody fragments derived from heavy-chain only IgG antibodies found in the Camelidae family. Due to their small size, simple structure, high antigen binding affinity, and remarkable stability in extreme conditions, nanobodies possess ...
Jin, Bo-Kyung +3 more
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