Results 41 to 50 of about 16,217 (195)
Biparatopic nanobodies targeting the receptor binding domain efficiently neutralize SARS-CoV-2
iScience, 2022 Summary: The development of therapeutics to prevent or treat COVID-19 remains an area of intense focus. Protein biologics, including monoclonal antibodies and nanobodies that neutralize virus, have potential for the treatment of active disease.
Phillip Pymm +23 more
doaj +1 more source
Nanobodies against Pfs230 block Plasmodium falciparum transmission
, 2022 Transmission blocking interventions can stop malaria parasite transmission from mosquito to human by inhibiting parasite infection in mosquitos. One of the most advanced candidates for a malaria transmission blocking vaccine is Pfs230.
Healer, J +13 more
core +2 more sources
SARS-CoV-2 binding nanobodies.
, 2021 Nanobodies with a solved crystal structures in complex with a SARS-CoV-2 antigen. Nanobodies were assigned to their nearest epitope cluster, as defined by Dejnirattisai et al. [28].
Wing Ki Wong (7497026) +5 more
core +1 more source
Revolutionizing antiviral therapy with nanobodies: Generation and prospects
Biotechnology Reports, 2023 As the world continues to grapple with infectious diseases, scientists are constantly searching for effective ways to combat these deadly pathogens. One promising avenue of research is the use of nanobodies as neutralization agents. These small proteins,
Mujahed I. Mustafa, Ahmed Mohammed
doaj +1 more source
Nanobodies as modulators of inflammation: potential applications for acute brain injury
Frontiers in Cellular Neuroscience, 2014 Nanobodies are single domain antibodies derived from llama heavy-chain only antibodies (HCAbs). They represent a new generation of biologicals with unique properties: nanobodies show excellent tissue distribution, high temperature and pH stability, are ...
Björn eRissiek +2 more
doaj +1 more source
Characterisation of anti-Mesothelin nanobodies in order to treat malignant pleural mesothelioma
, 2023 reservedThe malignant pleural mesothelioma, a neoplasm arising from mesothelioma cells, has a very poor prognosis since the standard chemotherapy has a bad response rate.
BUZIOL, LAURA
core
MicrobiologyOpen, 2022 Necrotic enteritis (NE), caused by Clostridium perfringens, is an intestinal disease with devastating economic losses to the poultry industry. NE is a complex disease and predisposing factors that compromise gut integrity are required to facilitate C ...
Dharanesh Gangaiah +8 more
doaj +1 more source
, 2023 reservedI carcinomi esofagei sono fra i tumori più aggressivi in quanto la sopravvivenza a 5 anni è inferiore al 20%. L’aumento allarmante del numero di casi nei paesi più sviluppati mette in risalto la necessità di sviluppare nuovi approcci ...
FRANZIN, ELISA
core
Design and engineering of functional nanobodies for biosensing applications
, 2023 Nanobodies are one type of antibody fragment that can be isolated from italicised{Camelidae} and sharks. Compared to the antibodies presented in mouse, rabbit and human, nanobodies display unique advantages such as improved stability and solubility ...
CHANG LIU (10830276)
core +1 more source
Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization. [PDF]
, 2017 Norovirus is the leading cause of gastroenteritis worldwide. Despite recent developments in norovirus propagation in cell culture, these viruses are still challenging to grow routinely.
Grant S Hansman +5 more
core +1 more source