Results 31 to 40 of about 14,448 (252)
Recombinant expression of nanobodies and nanobody-derived immunoreagents
Protein Expression and Purification, 2020 Antibody fragments for which the sequence is available are suitable for straightforward engineering and expression in both eukaryotic and prokaryotic systems. When produced as fusions with convenient tags, they become reagents which pair their selective binding capacity to an orthogonal function.
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Nanobody-Targeted Photodynamic Therapy: Nanobody Production and Purification
, 2022 Nanobodies have recently been introduced to the field of photodynamic therapy (PDT) as a very promising strategy to target photosensitizers selectively to cancer cells. Nanobodies are known for their characteristic small size (15 kDa), high specificity, and high binding affinities.
Mashayekhi, Vida +4 more
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The Therapeutic Potential of Nanobodies [PDF]
BioDrugs, 2019 Today, bio-medical efforts are entering the subcellular level, which is witnessed with the fast-developing fields of nanomedicine, nanodiagnostics and nanotherapy in conjunction with the implementation of nanoparticles for disease prevention, diagnosis, therapy and follow-up.
Ivana Jovčevska, Serge Muyldermans
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Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies
, 2023 Noroviruses are the leading cause of outbreaks of acute gastroenteritis. These viruses usually interact with histo-blood group antigens (HBGAs), which are considered essential cofactors for norovirus infection.
Marie Pancera +17 more
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Nanobodies against Pfs230 block Plasmodium falciparum transmission
, 2022 Transmission blocking interventions can stop malaria parasite transmission from mosquito to human by inhibiting parasite infection in mosquitos. One of the most advanced candidates for a malaria transmission blocking vaccine is Pfs230.
Healer, J +13 more
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SARS-CoV-2 binding nanobodies.
, 2021 Nanobodies with a solved crystal structures in complex with a SARS-CoV-2 antigen. Nanobodies were assigned to their nearest epitope cluster, as defined by Dejnirattisai et al. [28].
Wing Ki Wong (7497026) +5 more
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Nanobodies as modulators of inflammation: potential applications for acute brain injury
Frontiers in Cellular Neuroscience, 2014 Nanobodies are single domain antibodies derived from llama heavy-chain only antibodies (HCAbs). They represent a new generation of biologicals with unique properties: nanobodies show excellent tissue distribution, high temperature and pH stability, are ...
Björn eRissiek +2 more
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INDI – Integrated Nanobody Database for Immunoinformatics [PDF]
Nucleic Acids Research, 2021 Abstract Nanobodies, a subclass of antibodies found in camelids, are a versatile molecular binding scaffold composed of a single polypeptide chain. The small size of nanobodies bestows multiple therapeutic advantages (stability, tumor penetration) with the first therapeutic approval in 2018 cementing the clinical ...
Piotr Deszynski +7 more
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MicrobiologyOpen, 2022 Necrotic enteritis (NE), caused by Clostridium perfringens, is an intestinal disease with devastating economic losses to the poultry industry. NE is a complex disease and predisposing factors that compromise gut integrity are required to facilitate C ...
Dharanesh Gangaiah +8 more
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Design and engineering of functional nanobodies for biosensing applications
, 2023 Nanobodies are one type of antibody fragment that can be isolated from italicised{Camelidae} and sharks. Compared to the antibodies presented in mouse, rabbit and human, nanobodies display unique advantages such as improved stability and solubility ...
CHANG LIU (10830276)
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