Reperfusion of cerebral artery thrombosis by the GPIb–VWF blockade with the Nanobody ALX-0081 reduces brain infarct size in guinea pigs [PDF]
, 2013 Stefania Momi +5 more
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Recent advances in structural characterization of volume‐regulated anion channels (VRACs)
The Journal of Physiology, EarlyView.Abstract figure legend Native LRRC8 channels are obligatory heteromers comprising LRRC8A and at least one other paralogue (LRRC8B‐E) with an unknown stoichiometry. LRRC8A and LRRC8D homomers form non‐functional hexameric channels or hexameric channels with abnormal functional properties.
Erkan Karakas +2 more
wiley +1 more source
Synthesis, Preclinical Validation, Dosimetry, and Toxicity of 68Ga-NOTA-Anti-HER2 Nanobodies for iPET Imaging of HER2 Receptor Expression in Cancer [PDF]
, 2013 Catarina Xavier +9 more
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MINFLUX Nanoscopy: A “Brilliant” Technique Promising Major Breakthrough
Microscopy Research and Technique, Volume 88, Issue 5, Page 1264-1272, May 2025.Minflux localization microscopy technique allows for both nm‐scale resolution in imaging and up to 10 kHz speed in tracking of single molecules. ABSTRACT MINFLUX nanoscopy relies on the localization of single fluorophores with expected ~ 2 nm precision in 3D mapping, roughly one order of magnitude better than standard stimulated emission depletion ...
Marco Salerno +6 more
wiley +1 more source
Llama-derived Single Variable Domains (Nanobodies) Directed against Chemokine Receptor CXCR7 Reduce Head and Neck Cancer Cell Growth in Vivo [PDF]
, 2013 David Maussang +13 more
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Mass Spectrometry Reviews, Volume 44, Issue 3, Page 213-453, May/June 2025.Abstract The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022.
David J. Harvey
wiley +1 more source
MedComm, Volume 6, Issue 5, May 2025.Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes +4 more
wiley +1 more source
Intraoperative fluorescence delineation of head and neck cancer with a fluorescent Anti‐epidermal growth factor receptor nanobody [PDF]
, 2013 Pieter B.A.A. van Driel +11 more
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α‐Synuclein in Parkinson's Disease: From Bench to Bedside
Medicinal Research Reviews, Volume 45, Issue 3, Page 909-946, May 2025.ABSTRACT α‐Synuclein (α‐syn), a pathological hallmark of PD, is emerging as a bridging element at the crossroads between neuro/immune‐inflammatory responses and neurodegeneration in PD. Several evidence show that pathological α‐syn accumulates in neuronal and non‐neuronal cells (i.e., neurons, microglia, macrophages, skin cells, and intestinal cells ...
Gabriele Bellini +8 more
wiley +1 more source