Results 181 to 190 of about 16,593 (260)

A randomized, double-blind, placebo-controlled phase 1 study of multiple ascending doses of subcutaneous M1095, an anti–interleukin 17A/F nanobody, in moderate-to-severe psoriasis [PDF]

, 2019
D Švecová, Martin Lubell, Florence Casset‐Semanaz, Harald S. Mackenzie, Roland Grenningloh, James G. Krueger   +5 more
openalex   +1 more source

Single‐molecule validation and optimised protocols for the use of secondary nanobodies in multiplexed immunoassays

Journal of Microscopy, EarlyView.
Abstract Recently developed secondary nanobodies or single‐domain antibodies present a powerful tool for immunodetection. Unlike traditional antibodies, their monovalence enables pre‐association with primary antibodies prior to sample staining, presenting a straightforward affinity‐based antibody labelling solution.
Rebecca Saleeb, Judi O'Shaughnessy, Ryan Ferguson, Candace T. Adams, Mathew H. Horrocks   +4 more
wiley   +1 more source

Institute collection and analysis of Nanobodies (iCAN): a comprehensive database and analysis platform for nanobodies [PDF]

, 2017
Jing Zuo, Jian Li, Rongxin Zhang, Longsheng Xu, Hanhan Chen, Xiaohuan Jia, Zhipeng Su, Linhong Zhao, Xing Huang, Wei Xie   +9 more
openalex   +1 more source

Dual CEA/CD44 targeting to colorectal cancer cells using nanobody-conjugated hyaluronic acid-modified mesoporous silica nanoparticles with pH- and redox-sensitivity

, 2022
Xiying Fan, Tingting Wang, Min Ho Han, Yi Gu, Guochuan Sun, Xinying Peng, Qinghui Shou, Haipeng Song, Wenshuai Liu, Rui Nian   +9 more
openalex   +2 more sources

Localization, mechanism and reduction of renal retention of technetium‐99m labeled epidermal growth factor receptor‐specific nanobody in mice [PDF]

, 2010
Lea Olive Tchouate Gainkam, Vicky Caveliers, Nick Devoogdt, Christian Vanhove, Catarina Xavier, Otto C. Boerman, Serge Muyldermans, Axel Bossuyt, Tony Lahoutte   +8 more
openalex   +1 more source

Abscisic Acid and Calcium Signals Convergently Regulate Sugar Accumulation by Orchestrating the SRK2A/CIPK6‐ABI5‐TST2 Module in Citrus

Plant Biotechnology Journal, EarlyView.
ABSTRACT Abscisic acid (ABA) and calcium respectively work as crucial plant hormones and second signalling molecules in the regulation of fruit development and quality formation, including the sugar content and flavour quality. However, the regulatory mechanisms of fruit sugar accumulation arising from the interaction between ABA and calcium have not ...
Zuolin Mao, Mengdi Li, Siyang Gao, Zeqi Zhao, Xiawan Zhai, Ji‐Hong Liu, Lailiang Cheng, Chunlong Li   +7 more
wiley   +1 more source

A Versatile Synaptotagmin‐1 Nanobody Provides Perturbation‐Free Live Synaptic Imaging And Low Linkage‐Error in Super‐Resolution Microscopy [PDF]

, 2023
Karine Queiroz Zetune Villa Real, Nikolaos Mougios, Ronja Rehm, Shama Sograte‐Idrissi, László Albert, Amir Mohammad Rahimi, Manuel Maidorn, Jannik Hentze, Markel Martínez‐Carranza, Hassan Hosseini, Kim‐Ann Saal, Nazar Oleksiievets, Matthias Prigge, Roman Tsukanov, Pål Stenmark, Eugenio F. Fornasiero, Felipe Opazo   +16 more
openalex   +1 more source

Jasmonate‐Activated AaWRKY9–AabHLH93/AabHLH93–AaMYB7 Complexes Balance Artemisinin Biosynthesis in Artemisia annua

Plant Biotechnology Journal, EarlyView.
ABSTRACT Artemisinin, an antimalarial sesquiterpene lactone, is biosynthesized in glandular trichomes of Artemisia annua. Although numerous transcription factors have been demonstrated to regulate artemisinin biosynthesis, the molecular mechanisms underlying the high expression of artemisinin‐associated biosynthetic enzyme and transcription factor ...
Xueqing Fu, Han Zheng, Yaojie Zhang, Muyao Yu, Shu Li, Hang Liu, Pin Liu, Ling Li, Xiaofen Sun, Jingya Zhao, Yuliang Wang, Kexuan Tang   +11 more
wiley   +1 more source

The TaMADS2‐TaTBL21 Module Enhances Wheat Resistance to Stripe Rust by Activating TaGKL‐Mediated Immunity

Plant Biotechnology Journal, EarlyView.
ABSTRACT Wheat stripe rust (Puccinia striiformis f. sp. tritici, Pst) poses a catastrophic threat to global food security. While MADS‐box transcription factors regulate development and abiotic stress, their roles in plant‐pathogen immunity remain enigmatic.
Shijia Zhao, Hao Chu, Yanan Lu, Jiaqi Chen, Xu Wang, Guangxiang Tian, Mingjing Zhang, Pengyu Song, Yanhui Zhang, Guihua Bai, Gangming Zhan, Zhensheng Kang, Wenming Zheng, ZhengQing Fu, Na Liu   +14 more
wiley   +1 more source

Camelid immunoglobulins and nanobody technology [PDF]

, 2009
Baral, TN, De Baetselier, P, De Genst, E, Hassanzadeh-Ghassabeh, G, Kinne, J, Leonhardt, H, Magez, Stefan, Muyldermans, S, Nguyen, VK, Retarnozzo, VC, Revets, H, Rothbauer, U, Saerens, D, Stijemans, B, Tillib, S, Wernery, U, Wyns, L   +16 more
core   +1 more source