Results 221 to 230 of about 19,829 (313)

Antibody‐Nanoparticle Conjugates in Therapy: Combining the Best of Two Worlds

Small, Volume 21, Issue 15, April 16, 2025.
Antibody‐nanomaterial conjugates (ANCs) are an emerging therapeutic class combining the precise targeting specificity of antibodies with the versatility and functionality of nanomaterials. This review summarizes ANC design, synthesis, and potential therapeutic applications in this rapidly advancing field.
Aniruddha Adhikari, Irene A. Chen
wiley   +1 more source

The development and optimisation of nanobody based electrochemical immunosensors for IgG [PDF]

, 2016
Jack A. Goode, G. Dillon, Paul A. Millner   +2 more
openalex   +1 more source

A Modular Bacteriophage T4 Nanoparticle Platform Enables Rapid Design of Dual COVID‐19‐Flu Mucosal Vaccines

Small Science, Volume 5, Issue 4, April 2025.
A bacteriophage T4‐based mucosal vaccine platform is developed for dual protection against two highly transmissible respiratory diseases, COVID‐19 and flu. This adjuvant‐free vaccine incorporates multiple viral antigens into phage nanoparticle for high‐density display and intranasal delivery.
Jingen Zhu, Jian Sha, Himanshu Batra, Swati Jain, Xiaorong Wu, Emily K. Hendrix, Paul B. Kilgore, Keer Sun, Kenneth S. Plante, Jessica A. Plante, Jordyn Walker, Pan Tao, Ashok K. Chopra, Venigalla B. Rao   +13 more
wiley   +1 more source

Trends in nanobody technology in industrialization. [PDF]

Discov Nano
Wu Y.
europepmc   +1 more source

A general protocol for the generation of Nanobodies for structural biology

, 2014
Els Pardon, Toon Laeremans, Sarah Triest, Søren G. F. Rasmussen, Alexandre Wohlkönig, A. Ruf, Serge Muyldermans, Wim G. J. Hol, Brian K. Kobilka, Jan Steyaert   +9 more
openalex   +2 more sources

Thermodynamics of Nanobody Binding to Lactose Permease [PDF]

, 2016
Parameswaran Hariharan, Magnus Andersson, Xiaoxu Jiang, Els Pardon, Jan Steyaert, H. Ronald Kaback, Lan Guan   +6 more
openalex   +1 more source

Transition metal transporting P‐type ATPases: terminal metal‐binding domains serve as sensors for autoinhibitory tails

The FEBS Journal, Volume 292, Issue 7, Page 1654-1674, April 2025.
Copper is essential, yet toxic. High levels of copper are removed from the cells by proteins called P1B‐ATPases that have poorly understood metal‐binding domains (MBDs). Here, we present MBD structures from the P1B‐ATPase LpCopA, where a metal‐binding core senses copper conditions, enabling a flexible tail to block copper export at low concentrations ...
Qiaoxia Hu, Oleg Sitsel, Viktoria Bågenholm, Christina Grønberg, Pin Lyu, Anna Sigrid Pii Svane, Kasper Røjkjær Andersen, Nick Stub Laursen, Gabriele Meloni, Poul Nissen, Dennis W. Juhl, Jakob Toudahl Nielsen, Niels Chr. Nielsen, Pontus Gourdon   +13 more
wiley   +1 more source

Blockade of the vaspin-AP-1 axis inhibits arthritis development. [PDF]

Exp Mol Med
Jeon J, Cho C, Kim S, Kim H, Lee H, Kim SJ, Park H, Yu JH, Lee S, Lee KS, Jung J, Yang S.   +11 more
europepmc   +1 more source

Preclinical Evaluation of ¹⁸F-Labeled Anti-HER2 Nanobody Conjugates for Imaging HER2 Receptor Expression by Immuno-PET [PDF]

, 2016
Ganesan Vaidyanathan, Darryl McDougald, Jae‐Yeon Choi, Eftychia Koumarianou, Douglas H. Weitzel, Takuya Osada, H. Kim Lyerly, Michael R. Zalutsky   +7 more
openalex   +1 more source

A bivalent spike-targeting nanobody with anti-sarbecovirus activity. [PDF]

J Nanobiotechnology
Swart IC, Debski-Antoniak OJ, Zegar A, de Bouter T, Chatziandreou M, van den Berg M, Drulyte I, Pyrć K, de Haan CAM, Hurdiss DL, Bosch BJ, Oliveira S.   +11 more
europepmc   +1 more source