Results 211 to 220 of about 48,754 (252)

Direct recruitment of RNA Polymerase II by NANOG to activated target genes

open access: yes
Mullin NP   +7 more
europepmc   +1 more source

Pharmacological Inhibition of SP1 Reverses Cancer Stemness and Enhances Sorafenib Efficacy in Hepatocellular Carcinoma. [PDF]

open access: yesCells
Padelli M   +7 more
europepmc   +1 more source

Clinicopathological Significance of Pluripotent Factors in Sinonasal Intestinal-Type Adenocarcinoma. [PDF]

open access: yesCancers (Basel)
Monaco F   +14 more
europepmc   +1 more source

Nanog organizes transcription bodies [PDF]

open access: yesCurrent Biology, 2023
The localization of transcriptional activity in specialized transcription bodies is a hallmark of gene expression in eukaryotic cells.1-3 How proteins of the transcriptional machinery come together to form such bodies, however, is unclear. Here, we take advantage of two large, isolated, and long-lived transcription bodies that reproducibly form during ...
Kuznetsova, Ksenia   +9 more
openaire   +4 more sources

Stereospecific NANOG PEST Stabilization by Pin1 [PDF]

open access: yesBiochemistry
NANOG protein levels correlate with stem cell pluripotency. NANOG concentrations fluctuate constantly with low NANOG levels leading to spontaneous cell differentiation. Previous literature implicated Pin1, a phosphorylation-dependent prolyl isomerase, as a key player in NANOG stabilization.
Josephine C. Ferreon   +8 more
core   +5 more sources

Gene of the month: NANOG

Journal of Clinical Pathology, 2015
NANOG is the human ortholog of the mouse Nanog gene1 and is a member of the homeobox family of DNA binding transcription factors.2 NANOG plays an important role in the maintenance of pluripotency and self-renewal of human embryonic stem cells.3 ,4 Chambers et al 3 were the first researchers who identified this transcription factor and named it ...
Mireia, Mato Prado   +3 more
openaire   +2 more sources

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