Results 1 to 10 of about 56,636 (249)

Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis

Nature Communications, 2021
Nanopore sequencing technologies applied to transcriptome analysis suffer from high error rates, limiting them largely to reference-based analyses. Here, the authors develop a computational error correction method for transcriptome analysis that reduces ...
Kristoffer Sahlin, Botond Sipos, Phillip L. James, Paul Medvedev   +3 more
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Oncogene Concatenated Enriched Amplicon Nanopore Sequencing for rapid, accurate, and affordable somatic mutation detection

Genome Biology, 2021
We develop the Oncogene Concatenated Enriched Amplicon Nanopore Sequencing (OCEANS) method, in which variants with low variant allele frequency (VAFs) are amplified and subsequently concatenated for Nanopore Sequencing.
Deepak Thirunavukarasu, Lauren Y. Cheng, Ping Song, Sherry X. Chen, Mitesh J. Borad, Lawrence Kwong, Phillip James, Daniel J. Turner, David Yu Zhang   +8 more
doaj   +1 more source

Recent advances in ionic current rectification based nanopore sensing: a mini-review

Sensors and Actuators Reports, 2021
In recent years, the intensive studies have been devoted to nanopores due to their unique charge transport properties including ion permselectivity, ion concentration polarization, and ionic current rectification (ICR).
Shujie Zhang, Wei Chen, Laibo Song, Xiaohong Wang, Weilun Sun, Pengyun Song, Ghazala Ashraf, Bo Liu, Yuan-Di Zhao   +8 more
doaj   +1 more source

An Introduction to Nanopore Sequencing: Past, Present, and Future Considerations

Micromachines, 2023
There has been significant progress made in the field of nanopore biosensor development and sequencing applications, which address previous limitations that restricted widespread nanopore use.
Morgan MacKenzie, Christos Argyropoulos
doaj   +1 more source

Nanopore Technology and Its Applications in Gene Sequencing

Biosensors, 2021
In recent years, nanopore technology has become increasingly important in the field of life science and biomedical research. By embedding a nano-scale hole in a thin membrane and measuring the electrochemical signal, nanopore technology can be used to ...
Bo Lin, Jianan Hui, Hongju Mao
doaj   +1 more source

Nanopore sequencing-based genome assembly and evolutionary genomics of circum-basmati rice

Genome Biology, 2020
Background The circum-basmati group of cultivated Asian rice (Oryza sativa) contains many iconic varieties and is widespread in the Indian subcontinent.
Jae Young Choi, Zoe N. Lye, Simon C. Groen, Xiaoguang Dai, Priyesh Rughani, Sophie Zaaijer, Eoghan D. Harrington, Sissel Juul, Michael D. Purugganan   +8 more
doaj   +1 more source

Influence of Water on the Methane Adsorption Capacity of Organic-Rich Shales and Its Controlling Factors: A Review

Energies, 2023
A typical feature of shale gas reservoirs is that they contain a significant amount of adsorbed gas. The evaluation and prediction of adsorbed gas play important roles in shale gas exploration and development.
Yijie Xing, Xianming Xiao, Qin Zhou, Wei Liu, Yanming Zhao   +4 more
doaj   +1 more source

Genome Profiling of SARS-CoV-2 in Indonesia, ASEAN and the Neighbouring East Asian Countries: Features, Challenges and Achievements

Viruses, 2022
Whole-genome sequencing (WGS) has played a significant role in understanding the epidemiology and biology of SARS-CoV-2 virus. Here, we investigate the use of SARS-CoV-2 WGS in Southeast and East Asian countries as a genomic surveillance during the COVID-
Inswasti Cahyani, Eko W. Putro, Asep M. Ridwanuloh, Satrio Wibowo, Hariyatun Hariyatun, Gita Syahputra, Gilang Akbariani, Ahmad R. Utomo, Mohammad Ilyas, Matthew Loose, Wien Kusharyoto, Susanti Susanti   +11 more
doaj   +1 more source

Pore Structures for High-Throughput Nanopore Devices

Micromachines, 2020
Nanopore devices are expected to advance the next-generation of nanobiodevices because of their strong sensing and analyzing capabilities for single molecules and bioparticles. However, the device throughputs are not sufficiently high.
Sou Ryuzaki, Rintaro Matsuda, Masateru Taniguchi   +2 more
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Effects of cosolvents on CO2 displacement of shale oil and carbon storage

Petroleum Exploration and Development, 2023
Molecular dynamics method was used to establish composite wall/inorganic nanopores of three pore sizes, three shale oil systems, five CO2-cosolvent systems, and pure CO2 system.
Yifan ZHANG, Lu WANG, Rui ZOU, Run ZOU, Zhan MENG, Liang HUANG, Yisheng LIU, Hao LEI   +7 more
doaj   +1 more source