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An Introduction to Nanopore Sequencing: Past, Present, and Future Considerations
Micromachines, 2023 There has been significant progress made in the field of nanopore biosensor development and sequencing applications, which address previous limitations that restricted widespread nanopore use.
Morgan MacKenzie, Christos Argyropoulos
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Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis
Nature Communications, 2021 Nanopore sequencing technologies applied to transcriptome analysis suffer from high error rates, limiting them largely to reference-based analyses. Here, the authors develop a computational error correction method for transcriptome analysis that reduces ...
Kristoffer Sahlin +3 more
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Genome Biology, 2021 We develop the Oncogene Concatenated Enriched Amplicon Nanopore Sequencing (OCEANS) method, in which variants with low variant allele frequency (VAFs) are amplified and subsequently concatenated for Nanopore Sequencing.
Deepak Thirunavukarasu +8 more
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Recent advances in ionic current rectification based nanopore sensing: a mini-review
Sensors and Actuators Reports, 2021 In recent years, the intensive studies have been devoted to nanopores due to their unique charge transport properties including ion permselectivity, ion concentration polarization, and ionic current rectification (ICR).
Shujie Zhang +8 more
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Nanopore sequencing-based genome assembly and evolutionary genomics of circum-basmati rice
Genome Biology, 2020 Background The circum-basmati group of cultivated Asian rice (Oryza sativa) contains many iconic varieties and is widespread in the Indian subcontinent.
Jae Young Choi +8 more
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Pore Structures for High-Throughput Nanopore Devices
Micromachines, 2020 Nanopore devices are expected to advance the next-generation of nanobiodevices because of their strong sensing and analyzing capabilities for single molecules and bioparticles. However, the device throughputs are not sufficiently high.
Sou Ryuzaki +2 more
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Frontiers in Energy Research, 2021 Two-dimensional nanopores are very promising for high-permeance molecular sieving, but the molecular backflow from permeate-side to feed-side is not beneficial for improving molecular permeance.
Chengzhen Sun +3 more
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Barcode demultiplexing of nanopore sequencing raw signals by unsupervised machine learning
Frontiers in Bioinformatics, 2023 Introduction: Oxford Nanopore Technologies (ONT) is a third generation sequencing approach that allows the analysis of individual, full-length nucleic acids. ONT records the alterations of an ionic current flowing across a nano-scaled pore while a DNA or
Daniele M. Papetti +19 more
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MinION Analysis and Reference Consortium: Phase 1 data release and analysis [PDF]
, 2015 The advent of a miniaturized DNA sequencing device with a high-throughput contextual sequencing capability embodies the next generation of large scale sequencing tools.
Benedict Paten +23 more
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Forensic SNP genotyping using nanopore MinION sequencing [PDF]
, 2017 One of the latest developments in next generation sequencing is the Oxford Nanopore Technologies' (ONT) MinION nanopore sequencer. We studied the applicability of this system to perform forensic genotyping of the forensic female DNA standard 9947 A using
Cornelis, Senne +4 more
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