Results 1 to 10 of about 87,734 (276)
Error correction enables use of Oxford Nanopore technology for reference-free transcriptome analysis
Nature Communications, 2021 Nanopore sequencing technologies applied to transcriptome analysis suffer from high error rates, limiting them largely to reference-based analyses. Here, the authors develop a computational error correction method for transcriptome analysis that reduces ...
Kristoffer Sahlin +3 more
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Genome Biology, 2021 We develop the Oncogene Concatenated Enriched Amplicon Nanopore Sequencing (OCEANS) method, in which variants with low variant allele frequency (VAFs) are amplified and subsequently concatenated for Nanopore Sequencing.
Deepak Thirunavukarasu +8 more
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Recent advances in ionic current rectification based nanopore sensing: a mini-review
Sensors and Actuators Reports, 2021 In recent years, the intensive studies have been devoted to nanopores due to their unique charge transport properties including ion permselectivity, ion concentration polarization, and ionic current rectification (ICR).
Shujie Zhang +8 more
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Nanopore sequencing-based genome assembly and evolutionary genomics of circum-basmati rice
Genome Biology, 2020 Background The circum-basmati group of cultivated Asian rice (Oryza sativa) contains many iconic varieties and is widespread in the Indian subcontinent.
Jae Young Choi +8 more
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Frontiers in Energy Research, 2021 Two-dimensional nanopores are very promising for high-permeance molecular sieving, but the molecular backflow from permeate-side to feed-side is not beneficial for improving molecular permeance.
Chengzhen Sun +3 more
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Pore Structures for High-Throughput Nanopore Devices
Micromachines, 2020 Nanopore devices are expected to advance the next-generation of nanobiodevices because of their strong sensing and analyzing capabilities for single molecules and bioparticles. However, the device throughputs are not sufficiently high.
Sou Ryuzaki +2 more
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Barcode demultiplexing of nanopore sequencing raw signals by unsupervised machine learning
Frontiers in Bioinformatics, 2023 Introduction: Oxford Nanopore Technologies (ONT) is a third generation sequencing approach that allows the analysis of individual, full-length nucleic acids. ONT records the alterations of an ionic current flowing across a nano-scaled pore while a DNA or
Daniele M. Papetti +19 more
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De-novo Assembly of Limnospira fusiformis Using Ultra-Long Reads
Frontiers in Microbiology, 2021 The Limnospira genus is a recently established clade that is economically important due to its worldwide use in biotechnology and agriculture. This genus includes organisms that were reclassified from Arthrospira, which are commercially marketed as ...
McKenna Hicks +3 more
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MasterOfPores: A Workflow for the Analysis of Oxford Nanopore Direct RNA Sequencing Datasets
Frontiers in Genetics, 2020 The direct RNA sequencing platform offered by Oxford Nanopore Technologies allows for direct measurement of RNA molecules without the need of conversion to complementary DNA, fragmentation or amplification.
Luca Cozzuto +12 more
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LAFITE Reveals the Complexity of Transcript Isoforms in Subcellular Fractions
Advanced Science, 2023 Characterization of the subcellular distribution of RNA is essential for understanding the molecular basis of biological processes. Here, the subcellular nanopore direct RNA‐sequencing (DRS) of four lung cancer cell lines (A549, H1975, H358, and HCC4006)
Jizhou Zhang +7 more
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