Results 51 to 60 of about 87,734 (276)
MethPhaser: methylation-based long-read haplotype phasing of human genomes
Nature CommunicationsThe assignment of variants across haplotypes, phasing, is crucial for predicting the consequences, interaction, and inheritance of mutations and is a key step in improving our understanding of phenotype and disease.
Yilei Fu +6 more
doaj +1 more source
Recent progress in the methods of genome sequencing
Brazilian Archives of Biology and Technology, 2010 Genome sequencing is a very important tool for the development of genetic diagnosis, drugs of gene engineering, pharmacogenetics, etc. As the HGP comes into people's ears, there is an emerging need for the genome sequencing.
Zhao Ning-wei
doaj +1 more source
Cells, 2021 Objectives: Infections of the ascitic fluid are serious conditions that require rapid diagnosis and treatment. Ascites is often accompanied by other critical pathologies such as gastrointestinal bleeding and bowel perforation, and infection increases the
Hanna Goelz +5 more
doaj +1 more source
Controlling ion transport through nanopores: modeling transistor behavior [PDF]
, 2018 We present a modeling study of a nanopore-based transistor computed by a mean-field continuum theory (Poisson-Nernst-Planck, PNP) and a hybrid method including particle simulation (Local Equilibrium Monte Carlo, LEMC) that is able to take ionic ...
Boda, Dezső +4 more
core +2 more sources
Multiscale Structuring of Hydroxyapatite via Two‐Photon Lithography of Nanocomposites
Advanced Functional Materials, EarlyView.Hydroxyapatite scaffolds are of great interest in bone tissue engineering applications, ranging from 3D cell culture to regenerative medicine. Using two‐photon lithography of a transparent nanocomposite, hydroxyapatite microstructures with features ranging from submicron to centimeter‐scale are fabricated. This allows to mimic the natural bone geometry,
Leonhard Hambitzer +6 more
wiley +1 more source
Conical nanopore membranes: solvent shaping of nanopores [PDF]
Nanotechnology, 2006 We have undertaken a systematic investigation of the influence of ethanol on the shape of conical pores produced by the track-etch technique in poly(ethylene terephthalate) films. We have found that the cone angle of the conical nanopore generated is dependent on the amount of ethanol present in an alkaline etching solution.
P. SCOPECE +3 more
openaire +2 more sources
Advanced Functional Materials, EarlyView.Controlled laser‐drilling of embedded HfO2 membranes creates three layer nanopores with Gaussian‐shaped cavities sculptured in the supporting layers. These embedded solid‐state nanopores slow DNA translocation by 12‐fold compared to SiNx pores, enabling high‐resolution, label‐free detection of short DNAs, RNAs, and proteins.
Jostine Joby +4 more
wiley +1 more source
tRNA Modification Detection Using Graphene Nanopores: A Simulation Study
Biomolecules, 2017 There are over 100 enzyme-catalyzed modifications on transfer RNA (tRNA) molecules. The levels and identity of wobble uridine (U) modifications are affected by environmental conditions and diseased states, making wobble U detection a potential biomarker ...
Khadijah Onanuga +3 more
doaj +1 more source
Direct RNA Sequencing Unfolds the Complex Transcriptome of Vibrio parahaemolyticus
mSystems, 2021 Conventional bacterial genome annotation provides information about coding sequences but ignores untranslated regions and operons. However, untranslated regions contain important regulatory elements as well as targets for many regulatory factors, such as
Mohamad Al kadi +7 more
doaj +1 more source
Intrusion and extrusion of water in hydrophobic nanopores [PDF]
, 2017 Heterogeneous systems composed of hydrophobic nanoporous materials and water are capable, depending on their characteristics, of efficiently dissipating (dampers) or storing ("molecular springs") energy.
Casciola, Carlo Massimo +3 more
core +1 more source