Results 31 to 40 of about 110,323 (165)

Renal Phosphate Reabsorption in Humans Depends on at Least Three Distinct Transporters Unlike in Mice. [PDF]

Acta Physiol (Oxf)
ABSTRACT Aim Kidney excretion of phosphate is the gatekeeper of systemic phosphate homeostasis as evident from inborn and acquired diseases. Renal phosphate transporters are a promising target for phosphate‐lowering drugs, but molecular details of human kidney phosphate handling are largely unknown.
Fernandes AL, Lang L, Klar J, Giese A, Ehrmann A, Busch R, Auwerx H, Daniel C, Hernando N, Rubio-Aliaga I, Wagner CA.   +10 more
europepmc   +2 more sources

Upregulation of Intestinal NaPi-IIb Co-Transporter Gene Expression by Neuropeptide Y in Human Intestinal Caco-2 Cells [PDF]

The Open Gastroenterology Journal, 2009
The aim of the present study is to examine the effect of neuropeptide Y and estrogen on type IIb sodium- coupled phosphate co-transporter (NaPi-IIb) gene expression and activity.
K. Tsuchida, M. Saito, T. Nakahara, Kenji Sakamoto, K. Ishii   +4 more
semanticscholar   +2 more sources

Effects of Calcitonin on Porcine Intestinal Epithelial Cells Proliferation, Phosphorus Absorption, and NaPi-IIb Expression

Pakistan Journal of Zoology, 2019
Xiaopeng Tang, W. Su, R. Fang
semanticscholar   +2 more sources

The vitamin D analog ED-71 is a potent regulator of intestinal phosphate absorption and NaPi-IIb. [PDF]

Endocrinology, 2012
AbstractThe vitamin D analog ED-71 [1α,25-dihydroxy-2β-(3-hydroxypropyloxy)vitamin D3] has been approved for treatment of osteoporosis in Japan, but its effects on mineral metabolism have not been fully explored. We investigated the actions of ED-71 on phosphate (Pi) absorption and induction of the intestinal sodium/phosphate cotransporters.
Alex J. Brown, Fan-Jie Zhang, C. Ritter
semanticscholar   +3 more sources

Mechanisms of Epidermal Growth Factor Effect on Animal Intestinal Phosphate Absorption: A Review

Frontiers in Veterinary Science, 2021
Phosphorus is one of the essential mineral elements of animals that plays an important role in animal growth and development, bone formation, energy metabolism, nucleic acid synthesis, cell signal transduction, and blood acid–base balance.
Xiaopeng Tang, Xuguang Liu, Hu Liu
doaj   +1 more source

Functional characterization of the human intestinal NaPi-IIb cotransporter in hamster fibroblasts and Xenopus oocytes.

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2002
The recently cloned NaPi-IIb cotransporter is an apical membrane protein that is involved in the absorption of phosphate in the intestine. To expedite functional and structural studies, the human intestinal NaPi-IIb cotransporter was stably expressed in hamster fibroblast (PS120) cells.
Hua Xu, M. Inouye, Timothy Missey, J. Collins, F. Ghishan   +4 more
semanticscholar   +3 more sources

A third type of PETase from the marine Halopseudomonas lineage. [PDF]

Protein Sci
Abstract The enzymatic degradation of polyethylene terephthalate (PET) offers a sustainable solution for PET recycling. Over the past two decades, more than 100 PETases have been characterized, primarily exhibiting similar sequences and structures.
Turak O, Gagsteiger A, Upadhyay A, Kriegel M, Salein P, Böhnke-Brandt S, Agarwal S, Borchert E, Höcker B.   +8 more
europepmc   +2 more sources

Impaired phosphate transport in SLC34A2 variants in patients with pulmonary alveolar microlithiasis

Human Genomics, 2022
Background Variants in SLC34A2 encoding the sodium-dependent phosphate transport protein 2b (NaPi-IIb) cause the rare lung disease pulmonary alveolar microlithiasis (PAM).
Åsa Lina M. Jönsson, Nati Hernando, Thomas Knöpfel, Susie Mogensen, Elisabeth Bendstrup, Ole Hilberg, Jane Hvarregaard Christensen, Ulf Simonsen, Carsten A. Wagner   +8 more
doaj   +1 more source

Age quadratically affects intestinal calcium and phosphorus transporter gene expression in broiler chickens [PDF]

Animal Bioscience, 2022
Objective This research aimed to evaluate the effects of age on growth, tibia development, and intestinal calcium (Ca) and phosphorus (P) transporter gene expressions in broiler chickens.
Xianliang Lv, Junfang Hao, Lihua Wu, Mengyuan Liu, Lei He, Yingying Qiao, Yanyan Cui, Guan Wang, Chunmei Zhang, Hongxia Qu, Jincheng Han   +10 more
doaj   +1 more source

Mucosal expression of Ca and P transporters and claudins in the small intestine of broilers is altered by dietary Ca:P in a limestone particle size dependent manner.

PLoS ONE, 2022
High calcium (Ca) intake and fine limestone reduces precaecal phosphorus (P) absorption independently of P solubility in broilers. This study aimed to determine whether dietary total Ca: total P ratio (Ca:P) and limestone particle size (LPS) affect gene ...
Y X Hu, J van Baal, W H Hendriks, M Duijster, M M van Krimpen, P Bikker   +5 more
doaj   +1 more source