Results 51 to 60 of about 6,614 (186)
Coordination on Time-Varying Antagonistic Networks [PDF]
arXiv, 2021 This paper studies coordination problem for time-varying networks suffering from antagonistic information, quantified by scaling parameters. By such a manner, interacting property of the participating individuals and antagonistic information can be quantified in a fully decoupled perspective, thus benefiting from merely directed spanning tree ...
arxiv
Application and Assessment of Deep Learning for the Generation of Potential NMDA Receptor Antagonists [PDF]
, 2020 Uncompetitive antagonists of the N-methyl D-aspartate receptor (NMDAR) have demonstrated therapeutic benefit in the treatment of neurological diseases such as Parkinson's and Alzheimer's, but some also cause dissociative effects that have led to the synthesis of illicit drugs.
arxiv +1 more source
Strategic Management Journal, EarlyView.Abstract Research Summary Framing is critical for leaders who must build support for strategic renewal. While research has concentrated on renewal that replaces one set of capabilities with another, we explore a distinctive challenge: how leaders persuade stakeholders to endorse the reprioritization of resources toward a capability set that must ...
Ryan Raffaelli +3 more
wiley +1 more source
Inferring Synergistic and Antagonistic Interactions in Mixtures of Exposures [PDF]
arXiv, 2022 There is abundant interest in assessing the joint effects of multiple exposures on human health. This is often referred to as the mixtures problem in environmental epidemiology and toxicology. Classically, studies have examined the adverse health effects of different chemicals one at a time, but there is concern that certain chemicals may act together ...
arxiv
Academic Emergency Medicine, EarlyView.Abstract Background Pain management is a critical part of treatment in patients with chest trauma. Opioids and nonsteroidal anti‐inflammatory drugs have been the most commonly used medications. However, their side effects have drawn attention to other medications.
Hossein Zabihi Mahmoodabadi +4 more
wiley +1 more source
The antagonism of narcotics by L-3-Hydroxy-N-Allylmorphinan (Levallorphan) L-3-Hydroxy-N-Propargylmorphinan (Propallorophan) and 2,4-Diamino-5-Phenylthiazole (Daptazole) [PDF]
, 1957 Thesis (Ph.D.)--Boston UniversityIn this study, propallorphan (a-3-hydroxy-N-propargylmorphina.n, Ro-1-7780) was found to be a potent alphaprodine to alphaprodine in both dog and man.
Megirian, Robert
core
Border fortification and legibility: Evidence from Afghanistan
American Journal of Political Science, EarlyView.Abstract States often fortify their borders against militant threats. How do these efforts shape civilian welfare and perceptions in borderland communities? I conceptualize border fortification as a legibility‐building endeavor. By bolstering state reach in areas of weak historical penetration, fortification enhances the government's capacity for ...
Christopher W. Blair
wiley +1 more source
Antidepressant-like Effects of Neuropeptide SF (NPSF) [PDF]
World Journal of Research and Review (WJRR) ISSN:2455-3956,
Volume-4, Issue-5, May 2017 Pages 26-30, 2020 Neuropeptide SF (NPSF) is a member of RFamide neuropeptides that play diverse roles in central nervous system. Little is know about the effects of NPSF on brain functions. Antidepressant-like effect of NPSF was studied in modified mice FST. NPSF showed the antidepressant-like effects by decreasing the immobility time and increasing the climbing and ...
arxiv
, 2008 dissertationRecent investigations clarifying the monoaminergic influences on sympathetic preganglionic neurons in the cat have allowed a direct assessment of the effects of narcotic analgesics and antagonists on central transmission.
McCloskey, Kevin Lee.
core
British Journal of Pharmacology, EarlyView.Background and Purpose Hyoscine butylbromide (HBB) has a low oral (PO) bioavailability. Further, limited data on its activity on non‐gastrointestinal (GI) smooth muscle spasms after oral dosing are available, causing its effects beyond the GI tract to be questioned.
Sara Traserra +4 more
wiley +1 more source