Results 1 to 10 of about 323,886 (359)
Haematologica, 2009 Dasatinib, a dual tyrosine kinase inhibitor, is known to modulate or suppress T-cell activation and proliferation. We report a series of 8 patients who developed chronic peripheral lymphocytosis, identified as natural killer cells or natural killer/T ...
Dong Hwan Kim +7 more
doaj +4 more sources
T-cell dysfunction in natural killer/T-cell lymphoma
OncoImmunology, 2023 Natural killer/T-cell lymphoma (NKTCL) is an incurable aggressive T-cell lymphoma closely correlated with Epstein‒Barr virus (EBV) infection. Chronic and consistent viral infection induces T-cell exhaustion.
Xiaoyan Feng +8 more
doaj +3 more sources
Tumor Biology, 2017 Natural killer/T-cell lymphoma is a rare but aggressive neoplasm with poor prognosis. Despite previous reports that showed potential tumor suppressors, such as PRDM1 or oncogenes associated with the etiology of this malignancy, the role of long non ...
Esra Baytak +5 more
doaj +2 more sources
Germline natural killer cell receptors modulating the T cell response [PDF]
Frontiers in ImmunologyIn addition to their central role during innate responses, NK cells regulate adaptive immunity through various mechanisms. A wide array of innate receptors has been involved in the NK cell regulatory function.
Laura Mora-Bitria, Becca Asquith
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Natural Killer T Cell Activation Protects Mice Against Experimental Autoimmune Encephalomyelitis [PDF]
Journal of Experimental Medicine, 2001 Experimental autoimmune encephalomyelitis (EAE) serves as a prototypic model for T cell–mediated autoimmunity. Vα14 natural killer T (NKT) cells are a subset of T lymphocytes that recognize glycolipid antigens presented by the nonpolymorphic major ...
Avneesh K. Singh +9 more
semanticscholar +2 more sources
Pathogenesis and biomarkers of natural killer T cell lymphoma (NKTL)
Journal of Hematology & Oncology, 2019 Natural killer T cell lymphoma (NKTL) is an aggressive disease with very poor treatment outcomes in the advanced stages. With chemotherapy, initial response rates to treatment are high but responses are short lived.
Nagavalli Somasundaram +3 more
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Natural Killer T and Natural Killer Cell-Based Immunotherapy Strategies Targeting Cancer
Biomolecules, 2023 Both natural killer T (NKT) and natural killer (NK) cells are innate cytotoxic lymphoid cells that produce inflammatory cytokines and chemokines, and their role in the innate immune response to tumors and microorganisms has been investigated. Especially,
Tomonori Iyoda +4 more
doaj +1 more source
Extranodal Natural Killer/T-cell Lymphoma, Nasal Type: Diagnosis and Treatment
HemaSphere, 2021 The aggressive lymphoma, extranodal natural killer/T-cell lymphoma-nasal type, is strongly associated with Epstein-Barr virus (EBV) and is most common in Asia and in South and Central America. By contrast, incidence is low in the United States and Europe,
J. V. van Doesum +5 more
semanticscholar +1 more source
Journal of Medical Case Reports, 2020 Background Extranodal natural killer/T cell lymphoma, nasal type, is one of the more common subtypes of mature T cell lymphoma, especially in the Far East Asian population.
Yao-Chung Liu +7 more
doaj +1 more source
Natural killer T cell and pathophysiology of asthma [PDF]
Korean Journal of Pediatrics, 2010 Natural killer T (NKT) cell is a special type of T lymphocytes that has both receptor of natural killer (NK) cell (NK1.1, CD161c) and T cell (TCR) and express a conserved or invariant T cell receptor called V?#7284;J?#7288; in mice or Va24 in humans ...
Gwang Cheon Jang
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