Results 31 to 40 of about 323,886 (359)

Invariant Natural Killer T Cell Subsets—More Than Just Developmental Intermediates

Frontiers in Immunology, 2018
Invariant natural killer T (iNKT) cells are a CD1d-restricted T cell population that can respond to lipid antigenic stimulation within minutes by secreting a wide variety of cytokines.
S. Krovi, L. Gapin
semanticscholar   +1 more source

Reconstitution of natural killer cell receptors influences natural killer activity and relapse rate after haploidentical transplantation of T- and B-cell depleted grafts in children

Haematologica, 2010
Background Natural killer cells have been demonstrated to exert remarkable graft-versus-leukemia effects after haploidentical transplantation. Acquisition of both, inhibiting and activating, receptors on developing natural killer cells is an important ...
Matthias M. Pfeiffer, Tobias Feuchtinger, Heiko-Manuel Teltschik, Michael Schumm, Ingo Müller, Rupert Handgretinger, Peter Lang   +6 more
doaj   +1 more source

Dynamic Natural Killer Cell and T Cell Responses to Influenza Infection

Frontiers in Cellular and Infection Microbiology, 2020
Influenza viruses have perplexed scientists for over a hundred years. Yearly vaccines limit their spread, but they do not prevent all infections. Therapeutic treatments for those experiencing severe infection are limited; further advances are held back ...
Kayla Frank, Kayla Frank, Silke Paust, Silke Paust   +3 more
doaj   +1 more source

Reduced NK cell IFN-γ secretion and psychological stress are independently associated with herpes zoster. [PDF]

PLoS ONE, 2018
The pathogenesis of herpes zoster is closely linked to reduced varicella-zoster virus-specific cell-mediated immunity. However, little is known about the interplay between natural killer cells and psychological stress in the pathogenesis of herpes zoster.
Choon Kwan Kim, Youn Mi Choi, Eunsin Bae, Mihn Sook Jue, Hyung Seok So, Eung-Soo Hwang   +5 more
doaj   +1 more source

Frequent Mutations in Natural Killer/T Cell Lymphoma

Cellular Physiology and Biochemistry, 2018
Extranodal natural killer (NK)/T cell lymphoma (ENKTL-NT or NKTCL), with its aggressive nature and poor prognosis, has been widely studied to discover more effective treatment options.
Yanjie Zhang, Chaoping Li, Weili Xue, Mingzhi Zhang, Zhaoming Li   +4 more
doaj   +1 more source

Unraveling Natural Killer T-Cells Development [PDF]

Frontiers in Immunology, 2018
Natural killer T-cells are a subset of innate-like T-cells with the ability to bridge innate and adaptive immunity. There is great interest in harnessing these cells to improve tumor therapy; however, greater understanding of invariant NKT (iNKT) cell biology is needed. The first step is to learn more about NKT development within the thymus.
openaire   +3 more sources

Updating targets for natural killer/T-cell lymphoma immunotherapy

Cancer Biology & Medicine, 2021
Natural killer/T-cell lymphoma (NKTCL) is a highly invasive subtype of non-Hodgkin lymphoma, typically positive for cytoplasmic CD3, CD56, cytotoxic markers, including granzyme B and TIA1, and Epstein-Barr virus (EBV).
Weili Xue, Mingzhi Zhang
doaj   +1 more source

Extranodal Natural-Killer/T-Cell Lymphoma, Nasal Type

Advances in Hematology, 2010
The World Health Organization (WHO) classification recognizes 2 main categories of natural killer (NK) cell-derived neoplasms, namely, extranodal NK/T-cell lymphoma, nasal type, and aggressive NK-cell leukaemia.
Harinder Gill, Raymond H. S. Liang, Eric Tse   +2 more
doaj   +1 more source

Favorable impact of natural killer cell reconstitution on chronic graft-versus-host disease and cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation

Haematologica, 2014
Natural killer cells are the first lymphocyte subset to reconstitute, and play a major role in early immunity after allogeneic hematopoietic stem cell transplantation.
Vissal David Kheav, Marc Busson, Catherine Scieux, Régis Peffault de Latour, Guitta Maki, Philippe Haas, Marie-Christine Mazeron, Maryvonnick Carmagnat, Emeline Masson, Aliénor Xhaard, Marie Robin, Patricia Ribaud, Nicolas Dulphy, Pascale Loiseau, Dominique Charron, Gérard Socié, Antoine Toubert, Hélène Moins-Teisserenc   +17 more
doaj   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source