Results 31 to 40 of about 9,605,578 (343)

The Natural Products Atlas 2.0: a database of microbially-derived natural products

open access: yesNucleic Acids Res., 2021
Within the natural products field there is an increasing emphasis on the study of compounds from microbial sources. This has been fuelled by interest in the central role that microorganisms play in mediating both interspecies interactions and host ...
J. A. V. Santen   +15 more
semanticscholar   +1 more source

Antiplasmodial Natural Products [PDF]

open access: yesMolecules, 2011
Malaria is a human infectious disease that is caused by four species of Plasmodium. It is responsible for more than 1 million deaths per year. Natural products contain a great variety of chemical structures and have been screened for antiplasmodial activity as potential sources of new antimalarial drugs.
Nogueira, Claudio R.   +1 more
openaire   +4 more sources

Physalin A regulates the Nrf2 pathway through ERK and p38 for induction of detoxifying enzymes

open access: yesBMC Complementary and Alternative Medicine, 2019
Background Physalin A isolated from Physalis alkekengi var. franchetii has been known to have many pharmacological properties. However, its effect through the Nrf2 pathway has not yet been elucidated.
Ji Min Shin   +4 more
doaj   +1 more source

Identification of Tyrosinase Inhibitors and Their Structure-Activity Relationships via Evolutionary Chemical Binding Similarity and Structure-Based Methods

open access: yesMolecules, 2021
Tyrosinase is an enzyme that plays a crucial role in the melanogenesis of humans and the browning of food products. Thus, tyrosinase inhibitors that are useful to the cosmetic and food industries are required.
Prasannavenkatesh Durai   +4 more
doaj   +1 more source

Subcritical Water Extraction of Natural Products

open access: yesMolecules, 2021
Subcritical water refers to high-temperature and high-pressure water. A unique and useful characteristic of subcritical water is that its polarity can be dramatically decreased with increasing temperature.
Yan Cheng   +4 more
semanticscholar   +1 more source

Neuroprotective Natural Products for Alzheimer’s Disease

open access: yesCells, 2021
Alzheimer’s disease (AD) is the number one neurovegetative disease, but its treatment options are relatively few and ineffective. In efforts to discover new strategies for AD therapy, natural products have aroused interest in the research community and ...
Xin Chen   +3 more
semanticscholar   +1 more source

Natural Products for Antithrombosis [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2015
Thrombosis is considered to be closely related to several diseases such as atherosclerosis, ischemic heart disease and stroke, as well as rheumatoid arthritis, hyperuricemia, and various inflammatory conditions. More and more studies have been focused on understanding the mechanism of molecular and cellular basis of thrombus formation as well as ...
Cen Chen   +5 more
openaire   +2 more sources

Natural products as sources of new drugs over the 30 years from 1981 to 2010.

open access: yesJournal of Natural Products, 2012
This review is an updated and expanded version of the three prior reviews that were published in this journal in 1997, 2003, and 2007. In the case of all approved therapeutic agents, the time frame has been extended to cover the 30 years from January 1 ...
D. Newman, G. Cragg
semanticscholar   +1 more source

ChemInform Abstract: A Natural Love of Natural Products [PDF]

open access: yesChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
openaire   +4 more sources

Circaea mollis Siebold & Zucc. Alleviates postmenopausal osteoporosis in a mouse model via the BMP-2/4/Runx2 pathway

open access: yesBMC Complementary Medicine and Therapies, 2020
Background Circaea mollis Sieb. & Zucc. has been used as a traditional herbal medicine in Hani Ethnopharmacy and possesses anti-arthritic activities.
Ji Hye Park   +4 more
doaj   +1 more source

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