Results 101 to 110 of about 4,878 (179)

Evaluation of aggrephagy markers in myofibrillar myopathies

Acta Neuropathologica Communications
Myofibrillar Myopathies (MFMs) are a growing group of muscular disorders genetically determined, whose diagnosis is based on histological features as myofibrillar degeneration, Z-disk disorganization and protein aggregates’ accumulation.
Eliana Iannibelli, Alessandra Ruggieri, Antonello Maruotti, Franco Salerno, Marta Cheli, Alessandra Carnazzi, Lucia Nicolini De Gaetano, Giorgia Riolo, Sara Bortolani, Pietro Riguzzi, Sara Vianello, Gioia Merlonghi, Luca Bello, Matteo Garibaldi, Massimiliano Filosto, Stefano Carlo Previtali, Giorgio Tasca, Gaetano Vattemi, Paola Tonin, Elena Pegoraro, Sara Gibertini, Lorenzo Maggi   +21 more
doaj   +1 more source

Separate subversion of ATG8f or NBR1 by TBSV p33 replication protein into VROs.

(A) Confocal microscopy images show co-localization of eGFP-NBR1 and p33-RFP (top two panels), or eGFP-NBR1 and RFP-SKL co-expressing cYFP-p33 (bottom panels), within VROs in ATG8f-silenced (ATG8f KD) or control N. benthamiana cells.
Peter D. Nagy (7542872), Yuanrong Kang (6590813), Wenwu Lin (7542863)   +2 more
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Increased formation of punctate structures containing GFP-NBR1 under heat stress.

, 2013
(Top panel) Four-weeks old transgenic wild-type Col-0 (WT), atg7-2 and nbr1-1 mutant plants expressing GFP-NBR1 were treated with (45°C) or without (22°C) heat shock for 3 h and then placed at room temperature for 0.5 h.
Jing-Quan Yu (102564), Yuan Cheng (72244), Zhixiang Chen (23839), Ying-Jun Chi (102562), Baofang Fan (23837), Jian Wang (5901), Jie Zhou (28945)   +6 more
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Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. [PDF]

, 2009
The potential for modulation of growth factor signaling by endocytic trafficking of receptors is well recognized, but the underlying mechanisms are poorly understood.
Yekezare, Mona, Mardakheh, Faraz K, Machesky, Laura M., Heath, John K., Machesky, LM, Mardakheh, Faraz K., Mardakheh, FK, Laura M. Machesky, Heath, John, John K. Heath, Faraz K. Mardakheh, Machesky, Laura M, Heath, John K, Yekezare, M, Mona Yekezare   +14 more
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Peroxisome Proliferator Activator α Agonist Clofibrate Induces Pexophagy in Coconut Oil-Based High-Fat Diet-Fed Rats

Biology
Peroxisomes are crucial for fatty acid β-oxidation in steatosis, but the role of pexophagy—the selective autophagy of peroxisomes—remains unclear. This study investigated the effects of the peroxisome proliferator-activated receptor-α (PPARα) agonist ...
Kanami Ohshima, Emika Hara, Mio Takimoto, Yidan Bai, Mai Hirata, Wen Zeng, Suzuka Uomoto, Mai Todoroki, Mio Kobayashi, Takuma Kozono, Tetsuhito Kigata, Makoto Shibutani, Toshinori Yoshida   +12 more
doaj   +1 more source

NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube

, 2002
NBR1 (named as next to BRCA1) was originally cloned as a candidate gene for the ovarian cancer antigen CA125, using expression cloning with the anti-CA125 Ig, OC125. NBR1 has been of interest due to its position close to BRCA1, although no involvement in
Howe, K, Whitehouse, C, Sharpe, P, Chambers, J, Solomon, E, Cobourne, M; id_orcid   +5 more
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Particulate matter-induced NETosis promotes peroxisomal degradation via pexophagy in neutrophils

Ecotoxicology and Environmental Safety
Neutrophil extracellular traps (NETs) are chomatin-based structures that contribute to the defense mechanisms of a host; however, NETs can also drive inflammation when dysregulated. Particulate matter (PM), a major air pollutant, has been shown to induce
Yeji Shin, Kahyun Kim, Jisoo Han, Byounghwa Kim, Hyun Joung Lim, Jae-Young Um, Inhyung Lee, Hyun Jeong Kwak   +7 more
doaj   +1 more source

Data from: Brassinosteroids act as a positive regulator of NBR1-dependent selective autophagy in response to chilling stress in tomato

, 2019
<p>Autophagy is a highly conserved and regulated catabolic process involved in the degradation of protein aggregates, and it plays critical roles in eukaryotes. In plants, autophagy has been well studied in stress responses.
Zhou, Yanhong, Zhou, Jie, Li, Xiaomeng, Shi, Kai, Yu, Jing-Quan, Xia, Xiaojian, Chi, Cheng, Fang, Pingping   +7 more
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Identification of autophagy receptors for the Crohn’s disease-associated adherent-invasive Escherichia coli

Frontiers in Cellular and Infection Microbiology
IntroductionCrohn’s disease (CD) is a chronic inflammatory bowel disease, of which the etiology involves genetic, environmental and microbial factors.
Alison Da Silva, Guillaume Dalmasso, Anaïs Larabi, My Hanh Thi Hoang, My Hanh Thi Hoang, Elisabeth Billard, Nicolas Barnich, Hang Thi Thu Nguyen   +7 more
doaj   +1 more source

Structural and functional study of atg8 with sh3p2 and nbr1 in plant autophagy

, 2021
Autophagy is a catabolic process where cytosolic cellular components are delivered to the vacuole for degradation. Cargos could be recognized by autophagy receptors that bind to autophagy-related (ATG) 8 that decorates on the autophagosome membrane ...

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