Results 51 to 60 of about 107,878,294 (207)

Combined radiofrequency and topical exosomes in atrophic vulvar lichen sclerosus: A case report

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Vulvar lichen sclerosus (VLS) is a chronic inflammatory dermatological‐gynecological condition. Conventional first‐line treatment comprises topical corticosteroids; however, many patients remain refractory. Energy‐based devices, including radiofrequency (RF), have shown promising results in VLS, with symptomatic and functional improvement ...
Luisa Mendonca de Oliveira   +3 more
wiley   +1 more source

Emergence of NDM-1-producing Acinetobacter baumannii in China [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2011
To investigate the prevalence of bla(NDM-1) in Gram-negative bacilli in China.A total of 11 298 clinical Gram-negative bacilli, covering Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii and Pseudomonas aeruginosa, were collected for PCR-based surveillance of bla(NDM-1) from 57 hospitals representing 18 provinces in China. For bla(NDM-1)-
Yan, Chen   +3 more
openaire   +2 more sources

Discovery of a Novel Natural Allosteric Inhibitor That Targets NDM-1 Against Escherichia coli

open access: yesFrontiers in Pharmacology, 2020
At present, the resistance of New Delhi metallo-β-lactamase-1 (NDM-1) to carbapenems and cephalosporins, one of the mechanisms of bacterial resistance against β-lactam antibiotics, poses a threat to human health. In this work, based on the virtual ligand
Yanan Yang   +6 more
doaj   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi   +4 more
wiley   +1 more source

Emergence of NDM-1-producing Acinetobacter baumannii in Belgium [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2012
info:eu-repo/semantics ...
Bogaerts, Pierre   +7 more
openaire   +2 more sources

NDM-1 gene detection from Metallobeta lactamase (MBL) producing Pseudomonas aeruginosa: A pilot study from a teritiary care centre

open access: yes, 2019
<p>Multidrug resistant bacteria always remain a great challenge. The latest threat being New Delhi Metallobetalactamase-1 (NDM-1) a superbug has brought notoriety to Indian Health care.
S. Sangeetha   +2 more
core   +1 more source

Nosocomial Outbreak of New Delhi Metallo-β-Lactamase-1-Producing Gram-Negative Bacteria in South Africa: A Case-Control Study. [PDF]

open access: yesPLoS ONE, 2015
New Delhi metallo-β-lactamase (NDM)-producing Gram-negative bacteria have spread globally and pose a significant public health threat. There is a need to better define risk factors and outcomes of NDM-1 clinical infection.
Pieter de Jager   +4 more
doaj   +1 more source

Effect of Glutathione S‐Transferase and Metallothionein Polymorphisms on Mercury Levels and End‐Stage Renal Disease (ESRD) in Colombian Patients

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Epidemiological studies have demonstrated a link between chronic kidney disease (CKD) and environmental mercury (Hg) exposure. Colombia has a well‐documented history of artisanal and small‐scale gold mining, where Hg exposure affects miners and nearby riverside and urban populations. This study aimed to evaluate the effects of polymorphisms in
Diana M. Narváez   +16 more
wiley   +1 more source

NDM-1 Hazard in the Balkan States: Evidence of the First Outbreak of NDM-1-Producing Klebsiella pneumoniae in Bulgaria

open access: yesMicrobial Drug Resistance, 2018
New Delhi MBL (NDM) carbapenemase-producing Klebsiella pneumoniae has become one of the most concerning multidrug-resistant pathogens. The Balkan counties are considered a reservoir for the spread of such strains based on several reports documenting NDM infections after hospitalization in ...
Savov, E.   +5 more
openaire   +3 more sources

NDM-1-Producing Escherichia coli in Germany [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2011
The bla NDM-1 carbapenemase gene has now been identified among many different enterobacterial species from many countries ([1][1], [7][2], [10][3]-[14][4]). Its current spread has often been associated with importations from the Indian subcontinent.
Yvonne, Pfeifer   +5 more
openaire   +2 more sources

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