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Carbapenem-resistant Acinetobacter baumannii are recognised by the US Centers for Disease Control and Prevention (CDC) as an urgent threat [1]. The most prevalent mechanism of carbapenem resistance in Acinetobacter spp. is due to the presence of carbapenem-hydrolysing class D β-lactamases, with OXA-23 being the most common. The observed dispersion
Rodgers, Deja +10 more
openaire +5 more sources
Outbreak Of NDM-1-producing Klebsiella Pneumoniae In A Neonatal Unit In Colombia [PDF]
Six multiresistant, NDM-1-producing Klebsiella pneumoniae strains were recovered from an outbreak that affected six neonatal patients in a Colombian hospital. Molecular analysis showed that all of the isolates harbored the blaNDM-1, qnrA, and intI1 genes
Aguilar, M +9 more
core +1 more source
Diversity of New Delhi metallo-beta-lactamase-producing bacteria in China
Objectives: The prevalence and dissemination of diverse NDM-producing bacteria in China was investigated. Methods: We collected 1,162 isolates from 8 cities during December 2013 ∼ May 2015 in China.
Xiaofeng Hu +20 more
doaj +1 more source
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source
Provides an outline of the current research around medical tourism, especially its impact on Australians. Background Medical tourism is a burgeoning industry in our region.
Peter Leggat
core +1 more source
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang +9 more
wiley +1 more source
Discovery of NDM-1 inhibitors from natural products
Human health is seriously threatened by metallo-β-lactamase (MBL)-mediated bacterial antimicrobial resistance, among which New Delhi metallo-β-lactamase 1 (NDM-1) has received great attention due to its extensive substrate profile and high lateral gene transfer.
Cheng Shi +5 more
openaire +2 more sources
Draft Genome Sequences of Pandrug-Resistant Serratia marcescens Clinical Isolates Harboring bla NDM-1 [PDF]
The draft genome sequences of two clonal, pandrug-resistant Serratia marcescens clinical isolates were determined. The resistance phenotype was plasmid driven, as 14 of 17 resistance genes were present on large IncFIB(K), IncHI2, and IncA/C2 plasmids ...
Chakraborty, Trinad +6 more
core +1 more source
Discovery of a Novel Natural Allosteric Inhibitor That Targets NDM-1 Against Escherichia coli
At present, the resistance of New Delhi metallo-β-lactamase-1 (NDM-1) to carbapenems and cephalosporins, one of the mechanisms of bacterial resistance against β-lactam antibiotics, poses a threat to human health. In this work, based on the virtual ligand
Yanan Yang +6 more
doaj +1 more source
Abstract Background The prevalence of iron deficiency with anemia and iron deficiency without anemia (IDWA) during pregnancy have not been summarized, and evidence of the direct association of IDWA with adverse perinatal outcomes (APO) are unknown.
Lucky O. Lawani +6 more
wiley +1 more source

