Results 41 to 50 of about 24,768 (218)

A mechanistic approach to prove the efficacy of combination therapy against New Delhi metallo-β-lactamases producing bacterial strain: a molecular and biochemical approach

European Journal of Medical Research, 2020
Background NDM-1 is a novel broad-spectrum metallo-β-lactamase with the capability to grant resistance to almost all β-lactam antibiotics. Its widespread dissemination made treatment options a major challenge to combat, causing threat to public health ...
Lubna Maryam, Abid Ali, Shamsi Khalid, Asad U. Khan   +3 more
doaj   +1 more source

In vitro Activity of Pentamidine Alone and in Combination With Aminoglycosides, Tigecycline, Rifampicin, and Doripenem Against Clinical Strains of Carbapenemase-Producing and/or Colistin-Resistant Enterobacteriaceae [PDF]

, 2018
Enterobacteriaceae cause different types of community- and hospital-acquired infections. Moreover, the spread of multidrug-resistant Enterobacteriaceae is a public health problem and the World Health Organization pointed them among the pathogens in which
Cebrero Cangueiro, Tania, Cordero Matia, María Elisa, Labrador Herrera, Gema, Smani, Younes, Álvarez Marín, Rocío   +4 more
core   +1 more source

Mechanisms involved in acquisition of blaNDM genes by IncA/C2 and IncFIIY plasmids [PDF]

, 2016
blaNDM genes confer carbapenem resistance and have been identified on transferable plasmids belonging to different incompatibility (Inc) groups. Here we present the complete sequences of four plasmids carrying a blaNDM gene, pKP1-NDM-1, pEC2-NDM-3, pECL3-
Alikhan, Nabil-Fareed, Beatson, Scott A., Forde, Brian M., Partridge, Sally R., Paterson, David L., Petty, Nicola K., Sartor, Anna L., Schembri, Mark A., Sidjabat, Hanna E., Wailan, Alexander M., Walsh, Timothy R., Williamson, Deborah A., Yam, Wan Keat   +12 more
core   +4 more sources

Molecular eidemiology of carbapenem-resistant Enterobacter cloacae complex in a tertiary hospital in Shandong, China

BMC Microbiology, 2023
Background The increasing incidence and prevalence of carbapenem-resistant Enterobacter cloacae complex (CREC) poses great challenges to infection prevention and disease treatment.
Shengnan Hu, Wenyan Xie, Qiwen Cheng, Xiaoning Zhang, Xiutao Dong, Huaiqi Jing, Jiazheng Wang   +6 more
doaj   +1 more source

NDM-1 Cases and Outbreaks in Turkey

Mikrobiyoloji Bulteni, 2014
We are grateful to Hatipoğlu and Turhan [Mikrobiyol Bul 2014; 48(1): 188-9] for their interest in our study published in Mikrobiyol Bul 2013; 47(2): 382-4. As Hatipoğlu and Turhan mentioned in their comment, ertapenem is more sensitive than other carbapenem antibiotics for the identification of New Delhi Metallo-beta-lactamase (NDM-1) producers among ...
Yanik, Keramettin, Guney, Akif Koray, Karadag, Adil, Eroglu, Cafer   +3 more
openaire   +2 more sources

NDM-1-Producing Escherichia coli in Germany [PDF]

Antimicrobial Agents and Chemotherapy, 2011
The bla NDM-1 carbapenemase gene has now been identified among many different enterobacterial species from many countries ([1][1], [7][2], [10][3]-[14][4]). Its current spread has often been associated with importations from the Indian subcontinent.
Yvonne, Pfeifer, Wolfgang, Witte, Martin, Holfelder, Johann, Busch, Patrice, Nordmann, Laurent, Poirel   +5 more
openaire   +2 more sources

Oligopeptides as full-length New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors. [PDF]

PLoS ONE, 2017
'Superbug' bacteria producing NDM-1 enzyme causing wide public concern were first detected in a patient who visited India in 2008. It's an effective approach to combining β-lactam antibiotics with NDM-1 inhibitor for treating NDM-1 producing strain ...
Bingzheng Shen, Chengliang Zhu, Xiang Gao, Gang Liu, Jinchun Song, Yan Yu   +5 more
doaj   +1 more source

Copy Number Change of the NDM-1 sequence in a multidrug-resistant Klebsiella pneumoniae clinical isolate. [PDF]

PLoS ONE, 2013
The genetic features of the antimicrobial resistance of a multidrug resistant Klebsiella pneumoniae strain harboring bla NDM-1 were investigated to increase our understanding of the evolution of NDM-1.
Tzu-Wen Huang, Te-Li Chen, Ying-Tsong Chen, Tsai-Ling Lauderdale, Tsai-Lien Liao, Yi-Tzu Lee, Chien-Pei Chen, Yen-Ming Liu, Ann-Chi Lin, Ya-Hui Chang, Keh-Ming Wu, Ralph Kirby, Jui-Fen Lai, Mei-Chen Tan, Leung-Kei Siu, Chung-Ming Chang, Chang-Phone Fung, Shih-Feng Tsai   +17 more
doaj   +1 more source

Unusual association of NDM-1 with KPC-2 and armA among Brazilian Enterobacteriaceae isolates [PDF]

, 2015
We report the microbiological characterization of four New Delhi metallo-beta-lactamase-1 (bla(NDM-1))-producing Enterobacteriaceae isolated in Rio de Janeiro, Brazil.
Chebabo, A., Fehlberg, Lorena C., Gales, Ana Cristina, Kusano, E. J. U., Pereira, R. M. G., Pignatari, Antonio Carlos Campos, Quiles, Milene Gonçalves, Rocchetti, Talita Trevisani   +7 more
core   +1 more source

Sequential isolation in a patient of Raoultella planticola and Escherichia coli bearing a novel ISCR1 element carrying blaNDM-1.

PLoS ONE, 2014
BackgroundThe gene for New Delhi metallo-β-lactamase 1 (NDM-1) has been reported to be transmitted via plasmids which are easily transferable and capable of wide distribution.
Juan Li, Ruiting Lan, Yanwen Xiong, Changyun Ye, Min Yuan, Xinfeng Liu, Xia Chen, Deshan Yu, Bin Liu, Wenchao Lin, Xuemei Bai, Yan Wang, Qiangzheng Sun, Yiting Wang, Hongqing Zhao, Qiong Meng, Qiang Chen, Ailan Zhao, Jianguo Xu   +18 more
doaj   +1 more source