Results 41 to 50 of about 107,878,294 (207)

Zidovudine enhances activity of carbapenems against NDM-1-producing Enterobacteriaceae. [PDF]

, 2021
OBJECTIVES: To investigate the efficacy of zidovudine in combination with carbapenems against NDM-1-producing Enterobacteriaceae. METHODS: MICs were determined using the broth microdilution method.
Hu, Y, Coates, A, Yanmin Hu, Anthony Coates   +3 more
core   +1 more source

Copy Number Change of the NDM-1 sequence in a multidrug-resistant Klebsiella pneumoniae clinical isolate. [PDF]

PLoS ONE, 2013
The genetic features of the antimicrobial resistance of a multidrug resistant Klebsiella pneumoniae strain harboring bla NDM-1 were investigated to increase our understanding of the evolution of NDM-1.
Tzu-Wen Huang, Te-Li Chen, Ying-Tsong Chen, Tsai-Ling Lauderdale, Tsai-Lien Liao, Yi-Tzu Lee, Chien-Pei Chen, Yen-Ming Liu, Ann-Chi Lin, Ya-Hui Chang, Keh-Ming Wu, Ralph Kirby, Jui-Fen Lai, Mei-Chen Tan, Leung-Kei Siu, Chung-Ming Chang, Chang-Phone Fung, Shih-Feng Tsai   +17 more
doaj   +1 more source

Sequential isolation in a patient of Raoultella planticola and Escherichia coli bearing a novel ISCR1 element carrying blaNDM-1.

PLoS ONE, 2014
BackgroundThe gene for New Delhi metallo-β-lactamase 1 (NDM-1) has been reported to be transmitted via plasmids which are easily transferable and capable of wide distribution.
Juan Li, Ruiting Lan, Yanwen Xiong, Changyun Ye, Min Yuan, Xinfeng Liu, Xia Chen, Deshan Yu, Bin Liu, Wenchao Lin, Xuemei Bai, Yan Wang, Qiangzheng Sun, Yiting Wang, Hongqing Zhao, Qiong Meng, Qiang Chen, Ailan Zhao, Jianguo Xu   +18 more
doaj   +1 more source

Evolution for improved secretion and fitness may be the selective pressures leading to the emergence of two NDM alleles

, 2020
The New Delhi metallo-β-lactamase (NDM-1) mediates resistance to β-lactam antibiotics. NDM-1 was likely formed as the result of a gene fusion between sequences encoding the first six amino acids of cytoplasm-localised aminoglycosidase, AphA6, and a ...
Nouwens, Amanda S., Pegg, Cassandra L, Zalucki, Yaramah M., Jen, Freda E.-C., Zalucki, Yaramah M, Jen, Freda E-C, Pegg, Cassandra L., Jennings, Michael P, Jennings, Michael P., Nouwens, Amanda S, Schulz, Benjamin L., Schulz, Benjamin L   +11 more
core   +1 more source

Diversity of New Delhi metallo-beta-lactamase-producing bacteria in China

International Journal of Infectious Diseases, 2017
Objectives: The prevalence and dissemination of diverse NDM-producing bacteria in China was investigated. Methods: We collected 1,162 isolates from 8 cities during December 2013 ∼ May 2015 in China.
Xiaofeng Hu, Xuebing Xu, Xu Wang, Wencheng Xue, Haijian Zhou, Ling Zhang, Qiuxia Ma, Rongtao Zhao, Guozheng Li, Peng Li, Chuanfu Zhang, Yun Shi, Jian Wang, Leili Jia, Rongzhang Hao, Ligui Wang, Dayang Zou, Xuelin Liu, Shaofu Qiu, Hongbin Song, Yansong Sun   +20 more
doaj   +1 more source

Brain‐wide magnetic resonance imaging analysis of neurobehavioral comorbidities in temporal lobe epilepsy

Epilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), patients often present with neurobehavioral comorbidities encompassing affective and cognitive difficulties. Whereas the latter have been related to atypical connectivity of mesiotemporal and frontotemporal circuits, the brain basis of affective symptoms remains incompletely understood.
Fatemeh Fadaie, Benoit Caldairou, Boris C. Bernhardt, Andrea Bernasconi, Neda Bernasconi   +4 more
wiley   +1 more source

Kinetic Study of Laboratory Mutants of NDM-1 Metallo-beta-Lactamase and the Importance of an Isoleucine at Position 35. [PDF]

, 2016
peer reviewedTwo laboratory mutants of NDM-1 were generated by replacing the isoleucine at position 35 with threonine and serine residues: the NDM-1(I35T)and NDM-1(I35S)enzymes.
Perilli, Mariagrazia, Bottoni, Carlo, Kerff, Frédéric, Celenza, Giuseppe, Mercuri, Paola Sandra, Colapietro, Martina, Mercuri, Paola, Amicosante, Gianfranco, Galleni, Moreno, Matagne, André, Marcoccia, Francesca, Sabatini, Alessia   +11 more
core   +1 more source

Electronic Devices and Digital Therapeutics in Neuromuscular Diseases: Narrative Review on Current Applications in Patients' Management and Pharmacovigilance

Health Care Science, EarlyView.
Digital innovations are revolutionizing neuromuscular disease management by integrating wearable sensors, mobile applications, and telemedicine to enable continuous monitoring and personalized care. These technologies enhance diagnosis, treatment, and drug development fostering dynamic interaction between patients and clinicians paving the way toward ...
Ilaria Saltarella, Concetta Altamura, Paola Laghetti, Giuseppina Settanni, Nicola Savino, Angelo Galiano, Bodvaël Fraysse, Angelo Vacca, Jean‐François Desaphy   +8 more
wiley   +1 more source

Jaarbericht 2002 [PDF]

, 2002
Jaarlijkse publicatie van de NDM over verslaving en middelengebruik. In dit jaarbericht aandacht voor cannabis, cocaine, opiaten, ecstasy, amfetamine en verwante drugs, alcohol en tabak.
Verdurmen, J.E.E. (red.), Gageldonk, A. van (medew.), Rigter, H.G.M. (red.), Laar, M.W. van (red.), Cruts, A.A.N. (red.), Meijer, R.F. (red.), Ooyen, M.M.J. van (red.), Ketelaars, A.P.M. (medew.)   +7 more
core  

NDM-1 protein expression and purification.

, 2013
A. 6×His and sumo (small ubiquitin-related modifier) tagged NDM-1 was overexpressed in E.coli BL21(DE3) strain, the black arrow indicates the sumo-NDM-1 fusion protein. B. The cleaved NDM-1 protein was purified by S75 gel filtration chromatography.
Hualiang Jiang (19452), Lianchun Li (166558), Xu Shen (66684), Yuanyuan Wang (20181), Cai Guang-Yang (345537), Limin Chen (90676), Hong Liu (50694), Cheng Luo (48047), Lefu Lan (345536), Kaixian Chen (19449), Mingyue Zheng (180908), Zhongjie Liang (163372), Xiangqian Kong (166573), Keqin Kathy Li (202911), Yao Hong (345535)   +14 more
core   +1 more source