Results 61 to 70 of about 24,768 (218)

Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance [PDF]

, 2020
Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess
Anderson, Rosaleen, Bedernjak, Alexandre F., Cummings, Stephen P., Day, Kathryn M., Gray, Mark, Jones, Amanda L., Marrs, Emma C.L., Perry, John D., Varadi, Linda   +8 more
core   +2 more sources

Identification of a Potential Inhibitor (MCULE-8777613195-0-12) of New Delhi Metallo-β-Lactamase-1 (NDM-1) Using In Silico and In Vitro Approaches

Molecules, 2022
New Delhi metallo-β-lactamase-1 (NDM-1), expressed in different Gram-negative bacteria, is a versatile enzyme capable of hydrolyzing β-lactam rings containing antibiotics such as penicillins, cephalosporins, and even carbapenems.
Ghazala Muteeb, Md Tabish Rehman, Mohamed F. AlAjmi, Mohammad Aatif, Mohd Farhan, Sheeba Shafi   +5 more
doaj   +1 more source

Evaluation of FilmArray Multiplex PCR Test Results in Bloodstream Infections in Oncological Patients

Journal of Clinical Laboratory Analysis, EarlyView.
In this study conducted at an oncology hospital, BCID2 panel results for the rapid identification of microorganisms and resistance genes in positive blood culture samples were compared with conventional culture methods. The BCID2 panel provided faster results and showed a high correlation with traditional methods.
İpek Mumcuoğlu, Sevgi Şahin, Esra Tavukcu, Neşe İnan, Ayşe Semra Güreser, Serap Süzük Yıldız, Tuba Dal   +6 more
wiley   +1 more source

NDM-1-producing Vibrio parahaemolyticus isolated from imported seafood [PDF]

Journal of Antimicrobial Chemotherapy, 2018
International ...
Briet, Arnaud, Helsens, Nicolas, Delannoy, Sabine, Debuiche, Sabine, Brisabois, Anne, Midelet, Graziella, Granier, Sophie A   +6 more
openaire   +4 more sources

Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study. [PDF]

, 2019
Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST).
Aller, SD, Bruchmann, S, Clark, T, Coello Pelegrin, A, Cormican, M, Diez Benavente, E, Doyle, RM, Ellington, MJ, Harris, KA, Huggett, JF, McGrath, E, Moran-Gilad, J, Motro, Y, O'Sullivan, DM, Phelan, J, Phuong Thuy Nguyen, T, Shaw, LP, Stabler, RA, van Belkum, A, van Dorp, L, Woodford, N   +20 more
core   +4 more sources

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

Genomic epidemiology of NDM-1-encoding plasmids in latin American clinical isolates reveals insights into the evolution of multidrug resistance [PDF]

, 2017
Bacteria that produce the broad-spectrum Carbapenem antibiotic NewDelhi Metallo-b-lactamase (NDM) place a burden on health care systems worldwide, due to the limited treatment options for infections caused by them and the rapid global spread of this ...
Alberto Valderrama, Betsy E. Castro, Carolina Duarte, CDC, Eby M. Sim, Ian G. Charles, Jaime E. Castellanos, Javier Escobar-Perez, Jesus Silva-Sanchez, Leanne Haggerty, María V. Moncada, Mauricio Beltran, Narda Olarte, Natasha Vanegas, Nicola K. Petty, Ricaurte Alejandro Marquez-Ortiz, Ulises Garza-Ramos, World Health Organization   +17 more
core   +2 more sources

Vegetation Structure and Diversity Under Farmer Managed Natural Regeneration: A Comparison of Silvo‐Arable and Silvo‐Pastoral Systems in Kenya

Land Degradation &Development, EarlyView.
ABSTRACT Farmer Managed Natural Regeneration (FMNR) is a low‐cost, adaptable agroforestry practice that enhances land restoration by promoting systematic integration of naturally regenerating trees within farming systems through tree selection and management.
Irene Awino Ojuok, Madelon Lohbeck, Till Stellmacher, Ermias Aynekulu, Tony Rinaudo, Christian Borgemeister   +5 more
wiley   +1 more source

NDM-1-Producing Acinetobacter baumannii from Algeria [PDF]

Antimicrobial Agents and Chemotherapy, 2012
Over the last decade, nosocomial infections with Acinetobacter baumannii have been described with an increasing trend toward multidrug resistance, mostly in intensive care units (ICUs) ([6][1], [9][2], [11][3]). The main mechanism of resistance to carbapenems in A.
Boulanger, A., Naas, T., Fortineau, N., Figueiredo, S., Nordmann, P.   +4 more
openaire   +1 more source

New Delhi metallo-beta-lactamase 1-producing Enterobacteriaceae: emergence and response in Europe [PDF]

, 2010
The European NDM-1 Survey Participants: Manuela Caniça (Departamento de Doenças Infecciosas do INSA)Acquired carbapenemases confer extensive antibiotic resistance to Enterobacteriaceae and represent a public health threat. A novel acquired carbapenemase,
Giesecke, J ., Magiorakos, A. P., Monnet, D. L., O’Connor, F. Santos, Struelens, M. J., The European NDM-1 Survey Participants   +5 more
core