Results 71 to 80 of about 24,768 (218)

Scalar dark matter in the B-L model

, 2015
The B-L extension of the Standard Model requires the existence of right-handed neutrinos and naturally realizes the seesaw mechanism of neutrino mass generation.
Rodejohann, Werner, Yaguna, Carlos E.
core   +1 more source

Risedronate and Methotrexate Are High-Affinity Inhibitors of New Delhi Metallo-β-Lactamase-1 (NDM-1): A Drug Repurposing Approach

Molecules, 2022
Bacteria expressing New Delhi metallo-β-lactamase-1 (NDM-1) can hydrolyze β-lactam antibiotics (penicillins, cephalosporins, and carbapenems) and, thus, mediate multidrug resistance.
Ghazala Muteeb, Abdulrahman Alsultan, Mohd Farhan, Mohammad Aatif   +3 more
doaj   +1 more source

Automated Identification of Thermal Transitions in Conjugated Material Thin Films Using In Situ Optical Spectroscopy

Small Methods, EarlyView.
This study demonstrates the effectiveness of in situ UV−vis coupled with automated data analysis, namely, ATLAS, for fast and reliable identification of multiple thermal transition in conjugated polymer thin films. This ATLAS method will significantly accelerate the understanding of the phase behavior of D‐A polymers with important implications for ...
Doan Vu, Martyn Jevric, Alireza Samadani, Mats R. Andersson, Christopher R. McNeill, Brendan T. O'Connor, Harald Ade   +6 more
wiley   +1 more source

Structure, Genetics and Worldwide Spread of New Delhi Metallo-β-lactamase (NDM): a threat to public health [PDF]

, 2017
Background: The emergence of carbapenemase producing bacteria, especially New Delhi metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health concern.
Khan, Asad U, Maryam, Lubna, Zarrilli, Raffaele   +2 more
core   +1 more source

Genomic Insights into Carbapenem-Resistant Organisms Producing New Delhi Metallo-β-Lactamase in Live Poultry Markets

Microorganisms
New Delhi metallo-β-lactamase (NDM) is an enzyme that can degrade a wide range of β-lactam antibiotics. The widespread dissemination of the blaNDM gene, which encodes NDM, in animal-derived settings poses a threat to public health security.
Xueqiang Xin, Yi Yin, Jiayong Kong, Mianzhi Wang, Zhiqiang Wang, Ruichao Li   +5 more
doaj   +1 more source

Nosocomial Outbreak of New Delhi Metallo-β-Lactamase-1-Producing Gram-Negative Bacteria in South Africa: A Case-Control Study. [PDF]

PLoS ONE, 2015
New Delhi metallo-β-lactamase (NDM)-producing Gram-negative bacteria have spread globally and pose a significant public health threat. There is a need to better define risk factors and outcomes of NDM-1 clinical infection.
Pieter de Jager, Tobias Chirwa, Shan Naidoo, Olga Perovic, Juno Thomas   +4 more
doaj   +1 more source

Multiplex visual nucleic acid detection via isothermal cascaded transcription of fluorescent RNA aptamers

VIEW, EarlyView.
(1) Existing multiplex nucleic acid detection struggles to combine high sensitivity, visual readout, and instrument‐free use, which is vital for rapid infection and antibiotic resistance diagnosis. (2) We developed MAGIC, integrating isothermal cascaded amplification and fluorescent RNA aptamer transcription, achieving 10 aM sensitivity, 100% accuracy ...
Yu Tang, Na Luo, Binbin Xie, Jie Luo, Yaling Yuan, Junjie Fan, Zhiyong Liu, Haiyan Gao, Ming Chen, Kai Chang   +9 more
wiley   +1 more source

Emergence of NDM-1-producing Acinetobacter baumannii in Belgium [PDF]

Journal of Antimicrobial Chemotherapy, 2012
Case Reports ; Letter ; Research Support, Non-U.S.
Bogaerts, Pierre, Rezende de Castro, Roberta, Roisin, Sandrine, Deplano, Ariane, Huang, Te-Din, Hallin, Marie, Denis, Olivier, Glupczynski, Youri   +7 more
openaire   +1 more source

Discovering NDM-1 inhibitors using molecular substructure embeddings representations

Journal of Integrative Bioinformatics, 2023
Abstract NDM-1 (New-Delhi-Metallo-β-lactamase-1) is an enzyme developed by bacteria that is implicated in bacteria resistance to almost all known antibiotics. In this study, we deliver a new, curated NDM-1 bioactivities database, along with a set of unifying rules for managing different activity properties and inconsistencies.
Papastergiou, Thomas, Azé, Jérôme, Bringay, Sandra, Louet, Maxime, Poncelet, Pascal, Rosales-Hurtado, Miyanou, Vo-Hoang, Yen, Licznar-Fajardo, Patricia, Docquier, Jean-Denis, Gavara, Laurent   +9 more
openaire   +6 more sources

Resistance to carbapenems in non-typhoidal Salmonella enterica serovars from humans, animals and food [PDF]

, 2018
Non-typhoidal serovars of Salmonella enterica (NTS) are a leading cause of food-borne disease in animals and humans worldwide. Like other zoonotic bacteria, NTS have the potential to act as reservoirs and vehicles for the transmission of antimicrobial ...
Fernández, J., Guerra, B., Rodicio Rodicio, María del Rosario   +2 more
core   +3 more sources