Results 71 to 80 of about 107,878,294 (207)

Emergence of NDM-1-producing Klebsiella pneumoniae in Morocco [PDF]

Journal of Antimicrobial Chemotherapy, 2011
To analyse the mechanisms responsible for multidrug resistance in three carbapenem-resistant Klebsiella pneumoniae isolates recovered from two hospitalized patients and an outpatient from the same hospital in Rabat, Morocco.PCR and sequencing were used to search for β-lactamase genes.
Poirel, L., Benouda, A., Hays, C., Nordmann, P.   +3 more
openaire   +2 more sources

Marginal bone loss around implants – What does it mean?

Periodontology 2000, EarlyView.
Abstract Background Changes in peri‐implant marginal bone levels (MBL) constitute a central outcome in studies on implant therapy and reflect the integrity of the supporting tissues over time. Aim To summarize current evidence on MBL changes around dental implants, with emphasis on temporal patterns, methods of assessment and their clinical ...
Carlotta Dionigi, Kostas Bougas, Tord Berglundh, Jan Derks   +3 more
wiley   +1 more source

[NDM-1: the superbug?].

Le infezioni in medicina, 2012
A novel type of carbapenemase, New Delhi metallo beta-lactamase 1 (NDM 1), was first identified in 2008 in two Enterobacteriacea isolates, both recovered from a Swedish patient transferred from India. The emergence of NDM 1 is now reported from all continents, often in patients with a history of travel or hospitalization in the Indian subcontinent. The
S, Pittalis, F, Ferarro, V, Puro
openaire   +1 more source

ORFs in NDM-1 composite transposon.

, 2013
ORFs in NDM-1 composite transposon.
Kunikazu Yamane (343522), Mari Matsui (343521), Fumihiko Takeuchi (118220), Yoshichika Arakawa (183806), Tsuyoshi Sekizuka (249989), Makoto Ohnishi (82158), Akira Hishinuma (343523), Makoto Kuroda (249974)   +7 more
core   +1 more source

In‐Vitro Activity of Ceftazidime‐Avibactam and Comparator Agents Against Carbapenem‐Resistant Gram‐Negative Isolates at a Tertiary Care Hospital in Lahore, Pakistan: A Cross‐Sectional Study

MicrobiologyOpen, Volume 15, Issue 6, December 2026.
Of 210 consecutive non‐duplicate carbapenem‐resistant Gram‐negative isolates collected at a tertiary care hospital in Lahore, Pakistan (December 2024–May 2025), 200 had a ceftazidime‐avibactam (CAZ–AVI) result; 70.5% were susceptible (141/200; 95% CI 63.7–76.7). Susceptibility varied by sample source (p = 0.008), being highest in blood cultures (81.2%),
Faryal Yunus, Obaid Ur Rehman, Muhammad Murtaza, Safa Mazhar, Abedin Samadi, Ahmed Asad Raza   +5 more
wiley   +1 more source

Structure-activity relationship of captopril derivatives as New Delhi metallo beta-lactamase 1 inhibitors

ADMET and DMPK
Background and purpose New Delhi Metallo beta-lactamase-1 (NDM-1) is a zinc-dependent enzyme that confers resistance to several antibiotics; therefore, there is an urgent requirement for effective inhibitors.
Ikhlas Jarrar
doaj   +1 more source

Decision inertia in emergencies: Reasons to be cheerful ten years on

Journal of Occupational and Organizational Psychology, Volume 99, Issue 4, December 2026.
Abstract A decade on from the publication of Decision inertia: Deciding between least worst outcomes in emergency responses to disasters, this commentary reflects on the paper's contribution to understanding decision‐making in high‐stakes environments and its subsequent theoretical, methodological and practical impact.
Nicola Power, Laurence Alison
wiley   +1 more source

Detection of NDM-1-Producing Klebsiella pneumoniae in Kenya [PDF]

Antimicrobial Agents and Chemotherapy, 2011
ABSTRACT Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla
Poirel, Laurent, Revathi, Gunturu, Bernabeu, Sandrine, Nordmann, Patrice   +3 more
openaire   +2 more sources

SDS-PAGE (5 to 12%) gels of NDM-1 purification.

, 2013
Lane 1, Takara protein molecular weight marker; lane 2, boiled cell fraction of E. coli.BL21(DE3) containing pET30a-NDM-1 before induction; lane 3, boiled cell fraction of E. coli. BL21(DE3) containing pET30a-NDM-1 after a 14 h induction with 0.1 mM IPTG
Yongliang Fang (587682), Bingzheng Shen (587681), Yan Yu (56143), Yun Shi (172065), Heng Zheng (447307), Xin Cao (288308), Hui Chen (28597), Jiao Chen (447306), Xingzhen Lao (447305)   +8 more
core   +1 more source

Dichloroacetate Improves Animal Survival, Growth, Neuromuscular Activity, Mitochondrial Stress and Physiology, and Elevated Lactate in C. elegans pdha‐1 and dld‐1 RNAi Models of Pyruvate Dehydrogenase Complex Deficiency (PDCD)

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Pyruvate dehydrogenase complex (PDHc) deficiency (PDCD) is a primary mitochondrial disorder characterized by neurodevelopmental disability, altered intermediary metabolism, and early mortality. Dichloroacetate (DCA), a pyruvate analog, activates PDHc and remains under clinical investigation for treatment of PDCD.
Cristina Remes, Neal D. Mathew, Victoria Miranda, Suraiya Haroon, Tyler O'Hara, Vernon E. Anderson, Manuela Lavorato, Kelsey Keith, Rui Xiao, Eiko Nakamaru‐Ogiso, Marni J. Falk   +10 more
wiley   +1 more source