Results 21 to 30 of about 107,878,294 (207)

Inhibitor discovery of full-length New Delhi metallo-β-lactamase-1 (NDM-1). [PDF]

PLoS ONE, 2013
New Delhi metallo-β-lactmase-1 (NDM-1) has recently attracted extensive attention for its biological activities to catalyze the hydrolysis of almost all of β-lactam antibiotics.
Bingzheng Shen, Yan Yu, Hui Chen, Xin Cao, Xingzhen Lao, Yongliang Fang, Yun Shi, Jiao Chen, Heng Zheng   +8 more
doaj   +1 more source

egemenimre/ccsds-ndm: Minor fix for Combined NDM output to KVN

, 2021
Added proper error message to Combined NDM output to ...
Egemen Imre, Tevfik Uyar, Agit
core   +1 more source

egemenimre/ccsds-ndm: Version 2.0

, 2021
This version adds KVN read / write support.
Egemen Imre
core   +1 more source

Identification of New Delhi metallo-β-lactamase 1 in Acinetobacter lwoffii of food animal origin. [PDF]

PLoS ONE, 2012
BackgroundTo investigate the presence of metallo-β-lactamase (MBL) genes and the genetic environment of the New Delhi metallo-β-lactamase gene bla(NDM-1) in bacteria of food animal origin.Methodology/principal findingsGram-negative bacteria with low ...
Yang Wang, Congming Wu, Qijing Zhang, Jing Qi, Hebing Liu, Yu Wang, Tao He, Licai Ma, Jing Lai, Zhangqi Shen, Yuqing Liu, Jianzhong Shen   +11 more
doaj   +1 more source

Emergence of NDM-1-Producing Enterobacteriaceae in Belgium [PDF]

Antimicrobial Agents and Chemotherapy, 2011
ABSTRACT Five multidrug-resistant nonclonally related Enterobacteriaceae isolates were recovered in Belgium in 2010 from three patients who had been hospitalized in Pakistan, Montenegro, and Serbia/Kosovo.
Bogaerts, Pierre, Bouchahrouf, Warda, Rezende de Castro, Roberta, Deplano, Ariane, Berhin, Catherine, Pierard, Denis, Denis, Olivier, Glupczynski, Youri   +7 more
openaire   +4 more sources

Higher isolation of NDM-1 producing Acinetobacter baumannii from the sewage of the hospitals in Beijing. [PDF]

PLoS ONE, 2014
Multidrug resistant microbes present in the environment are a potential public health risk. In this study, we investigate the presence of New Delhi metallo-β-lactamase 1 (NDM-1) producing bacteria in the 99 water samples in Beijing City, including river ...
Chuanfu Zhang, Shaofu Qiu, Yong Wang, Lihua Qi, Rongzhang Hao, Xuelin Liu, Yun Shi, Xiaofeng Hu, Daizhi An, Zhenjun Li, Peng Li, Ligui Wang, Jiajun Cui, Pan Wang, Liuyu Huang, John D Klena, Hongbin Song   +16 more
doaj   +1 more source

Emerione A, a novel fungal metabolite as an inhibitor of New Delhi metallo-β-lactamase 1, restores carbapenem susceptibility in carbapenem-resistant isolates

Journal of Global Antimicrobial Resistance, 2022
: Objectives: Bacterial strains that produce New Delhi metal-β-lactamase 1 (NDM-1) are a worldwide health threat. It remains a challenging task to find a potent NDM-1 inhibitor for clinical practice.
Yan He, Shupeng Zhou, Weiguang Sun, Qin Li, Jianping Wang, Jinwen Zhang   +5 more
doaj   +1 more source

Data_Sheet_1_PHT427 as an effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor restored the susceptibility of meropenem against Enterobacteriaceae producing NDM-1.docx

, 2023
IntroductionWith the increasingly serious problem of bacterial drug resistance caused by NDM-1, it is an important strategy to find effective inhibitors to assist β-lactam antibiotic treatment against NDM-1 resistant bacteria.
Xiaohui Li (73588), Sihan Liu (8704005), Qian Wang (32718), Tianjun Liu (1746298), Chunling Xiao (1523329), Xiao Wang (19312), Yishuang Liu (2196715), Yan Guan (1405984), Ji Zheng (1728028), Chennan Liu (15301489), Jiangxue Han (9645977)   +10 more
core   +1 more source

Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates

Acta Pharmaceutica Sinica B, 2021
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no promising ...
Bing Zhao, Xinhui Zhang, Tingting Yu, Ying Liu, Xiaoling Zhang, Yongfang Yao, Xuejian Feng, Hongmin Liu, Dequan Yu, Liying Ma, Shangshang Qin   +10 more
doaj   +1 more source

Evaluation of co-transfer of plasmid-mediated fluoroquinolone resistance genes and bla NDM gene in Enterobacteriaceae causing neonatal septicaemia

Antimicrobial Resistance and Infection Control, 2019
Background The bla NDM-1 (New Delhi Metallo-β-lactamase-1) gene has disseminated around the globe. NDM-1 producers are found to co-harbour resistance genes against many antimicrobials, including fluoroquinolones.
Shravani Mitra, Suchandra Mukherjee, Sharmi Naha, Pinaki Chattopadhyay, Shanta Dutta, Sulagna Basu   +5 more
doaj   +1 more source