Results 31 to 40 of about 107,878,294 (207)

NDM-1 Cases and Outbreaks in Turkey

open access: yesMikrobiyoloji Bulteni, 2014
We are grateful to Hatipoğlu and Turhan [Mikrobiyol Bul 2014; 48(1): 188-9] for their interest in our study published in Mikrobiyol Bul 2013; 47(2): 382-4. As Hatipoğlu and Turhan mentioned in their comment, ertapenem is more sensitive than other carbapenem antibiotics for the identification of New Delhi Metallo-beta-lactamase (NDM-1) producers among ...
Yanik, Keramettin   +3 more
openaire   +2 more sources

NDM-1–ProducingKlebsiella pneumoniae, Croatia [PDF]

open access: yesEmerging Infectious Diseases, 2012
Objectives: A K. pneumoniae strain, resistant to carbapenems, was isolated in May 2009, from a blood culture of a 40-years-old man, recovered in a surgical intensive care unit of the Clinical Hospital Center in Zagreb, Croatia.The patient had been transferred from another hospital of a neighbouring country after 5 days of hospitalization due to a car ...
MAZZARIOL, Annarita   +6 more
openaire   +3 more sources

Sequence of closely related plasmids encoding bla(NDM-1) in two unrelated Klebsiella pneumoniae isolates in Singapore. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: Spread of the bla(NDM-1) gene that encodes the New Delhi metallo-β-lactamase (NDM-1) in Enterobacteriaceae is a major global health problem.
Ying-Tsong Chen   +3 more
doaj   +1 more source

Discovery of novel new Delhi metallo-β-lactamases-1 inhibitors by multistep virtual screening.

open access: yesPLoS ONE, 2015
The emergence of NDM-1 containing multi-antibiotic resistant "Superbugs" necessitates the needs of developing of novel NDM-1inhibitors. In this study, we report the discovery of novel NDM-1 inhibitors by multi-step virtual screening.
Xuequan Wang   +4 more
doaj   +1 more source

Characterisation of ST25 NDM-1-producing Acinetobacter spp. strains leading the increase in NDM-1 emergence in Argentina

open access: yesJournal of Global Antimicrobial Resistance, 2020
Carbapenem-resistant Acinetobacter baumannii are recognised by the US Centers for Disease Control and Prevention (CDC) as an urgent threat [1]. The most prevalent mechanism of carbapenem resistance in Acinetobacter spp. is due to the presence of carbapenem-hydrolysing class D β-lactamases, with OXA-23 being the most common. The observed dispersion
Rodgers, Deja   +10 more
openaire   +5 more sources

Increase in NDM-1 and NDM-1/OXA-48-producing Klebsiella pneumoniae in Germany associated with the war in Ukraine, 2022

open access: yesEurosurveillance, 2022
In 2022, German surveillance systems observed rapidly increasing numbers of NDM-1- and NDM-1/OXA-48-producing Klebsiella pneumoniae , which may in part reflect recurring pre-pandemic trends. Among these cases, however, a presence in Ukraine before diagnosis was frequently reported.
Mirco Sandfort   +12 more
openaire   +4 more sources

A mechanistic approach to prove the efficacy of combination therapy against New Delhi metallo-β-lactamases producing bacterial strain: a molecular and biochemical approach

open access: yesEuropean Journal of Medical Research, 2020
Background NDM-1 is a novel broad-spectrum metallo-β-lactamase with the capability to grant resistance to almost all β-lactam antibiotics. Its widespread dissemination made treatment options a major challenge to combat, causing threat to public health ...
Lubna Maryam   +3 more
doaj   +1 more source

Molecular eidemiology of carbapenem-resistant Enterobacter cloacae complex in a tertiary hospital in Shandong, China

open access: yesBMC Microbiology, 2023
Background The increasing incidence and prevalence of carbapenem-resistant Enterobacter cloacae complex (CREC) poses great challenges to infection prevention and disease treatment.
Shengnan Hu   +6 more
doaj   +1 more source

Oligopeptides as full-length New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors. [PDF]

open access: yesPLoS ONE, 2017
'Superbug' bacteria producing NDM-1 enzyme causing wide public concern were first detected in a patient who visited India in 2008. It's an effective approach to combining β-lactam antibiotics with NDM-1 inhibitor for treating NDM-1 producing strain ...
Bingzheng Shen   +5 more
doaj   +1 more source

Horizontal transfer of antibiotic resistance genes on abiotic touch surfaces: implications for public health

open access: yes, 2012
Horizontal gene transfer (HGT) is largely responsible for increasing incidence of antibiotic-resistant infections worldwide. Whilst studies have focussed on HGT in vivo, this work investigates whether the ability of pathogens to persist in the ...
Warnes, S.L.   +5 more
core   +1 more source

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