Results 101 to 110 of about 63,496 (250)

The Spread of NDM-1 and NDM-7-Producing Klebsiella pneumoniae Is Driven by Multiclonal Expansion of High-Risk Clones in Healthcare Institutions in the State of Pará, Brazilian Amazon Region

open access: yesAntibiotics, 2021
Carbapenem resistance among Klebsiella pneumoniae isolates is often related to carbapenemase genes, located in genetic transmissible elements, particularly the blaKPC gene, which variants are spread in several countries.
Yan Corra Rodrigues   +4 more
semanticscholar   +1 more source

BIEN: A biodiversity informatics ecosystem advancing open and reproducible workflows for plant observation, plot and trait data

open access: yesMethods in Ecology and Evolution, EarlyView.
Abstract The rapid expansion of biodiversity data presents new opportunities to understand and forecast biosphere dynamics. However, disparate and dispersed data, taxonomic and geographic inconsistencies, pervasive quality issues, and a lack of reproducable workflows hinder synthesis, introduce biases and limit accurate assessment of biodiversity ...
Brian J. Enquist   +38 more
wiley   +1 more source

Evolution of carbapenem resistance in klebsiella pneumoniae and escherichia coli carrying bla NDM−1 gene: imipenem exposure results in sustained resistance memory of strains in vitro

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2023
Background Antibiotics exert an outstanding selective pressure on bacteria, forcing their chromosomal gene mutations and drug resistance genes to spread.
Qiong Zhao   +9 more
doaj   +1 more source

Discovery of thiosemicarbazone derivatives as effective New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors against NDM-1 producing clinical isolates

open access: yesActa Pharmaceutica Sinica B, 2020
New Delhi metallo-β-lactamase-1 (NDM-1) is capable of hydrolyzing nearly all β-lactam antibiotics, posing an emerging threat to public health. There are currently less effective treatment options for treating NDM-1 positive “superbug”, and no promising ...
Bing Zhao   +10 more
semanticscholar   +1 more source

Rethinking areas of endemism and barriers: perspectives for a causal historical biogeography and a critique of Schultz and Cracraft (2024)

open access: yesCladistics, EarlyView.
Abstract Historical biogeography faces a persistent conceptual and methodological dilemma concerning the nature of its central analytical units. Using the recent proposal by Schultz and Cracraft (Cladistics 40, 653) as a catalyst, this article critiques the argument that causal inference necessitates the replacement of areas of endemism with barriers ...
Augusto Ferrari
wiley   +1 more source

Legacy of the influenza pandemic 1918: The host T cell response

open access: yesBiomedical Journal, 2018
The influenza virus was instrumental in unravelling critical aspects of the antiviral T lymphocyte mediated immune response. A major finding was the demonstration that CD8 T lymphocytes recognize short viral peptides presented by class I molecules of the
Andrew J. McMichael
doaj   +1 more source

Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinoma

open access: yesLife Science Alliance, 2023
This pan-genomic study of crosstalk between HIF and AHR transcription factors reveals both antagonistic and cooperative interactions and highlights their relevance to kidney cancer and its treatment.
Véronique N Lafleur   +4 more
doaj   +1 more source

Anomalous force-velocity relation of driven inertial tracers in steady laminar flows

open access: yes, 2017
We study the nonlinear response to an external force of an inertial tracer advected by a two-dimensional incompressible laminar flow and subject to thermal noise.
Cecconi, F.   +3 more
core   +1 more source

Emergence of a novel mobile colistin resistance gene, mcr-8, in NDM-producing Klebsiella pneumoniae

open access: yesEmerging Microbes and Infections, 2018
The rapid increase in carbapenem resistance among gram-negative bacteria has renewed focus on the importance of polymyxin antibiotics (colistin or polymyxin E). However, the recent emergence of plasmid-mediated colistin resistance determinants (mcr-1, -2,
Xiaoming Wang   +9 more
semanticscholar   +1 more source

Increased Risk of Acquisition of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) among a Cohort of COVID-19 Patients in a Teaching Hospital in Tuscany, Italy

open access: yesPathogens, 2020
We describe the epidemiology of New Delhi Metallo-Beta-Lactamase-Producing Carbapenem-Resistant Enterobacterales (NDM-CRE) colonization/infection in a cohort of COVID-19 patients in an Italian teaching hospital.
A. Porretta   +10 more
semanticscholar   +1 more source

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