Results 121 to 130 of about 3,616 (145)

Uropathogenic Escherichia coli Subverts Host Autophagic Defenses by Stalling Preautophagosomal Structures to Escape Lysosome Exocytosis. [PDF]

J Infect Dis
Li X, Jiang L, Zhang S, Zhou J, Liu L, Jin C, Sun H, Wang Q, Liu Y, Pang Y.   +9 more
europepmc   +1 more source

African swine fever virus MGF505-4R facilitates cGAS degradation through TOLLIP-mediated selective autophagy and inhibits the formation of ISGF3 to evade innate immunity. [PDF]

Vet Res
Yao M, Li P, Li X, Li W, Qian P.
europepmc   +1 more source

Advances in understanding mitophagy's role in lung injury. [PDF]

Chin J Traumatol
Du W, Yang Y, Zhang T, Jiang J, Du D, Huang G, Tao S.   +6 more
europepmc   +1 more source

ALDH1L1 suppresses the replication of porcine epidemic diarrhea virus by degrading viral nucleocapsid and envelope proteins. [PDF]

J Virol
Wang J, Zeng Y, Liu Y, Sun H, Gao A, Zheng D, Tong W, Yu H, Zheng H, Tong G, Cao X, Kong N, Shan T.   +12 more
europepmc   +1 more source

Mechanistic insights into the interactions of NAP1 with the SKICH domains of NDP52 and TAX1BP1 [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2018
NDP52 and TAX1BP1, two SKIP carboxyl homology (SKICH) domain-containing autophagy receptors, play crucial roles in selective autophagy. The autophagic functions of NDP52 and TAX1BP1 are regulated by TANK-binding kinase 1 (TBK1), which may associate with them through the adaptor NAP1.
Tao Fu, Jianping Liu, Yingli Wang
exaly   +5 more sources

Rab35 GTPase recruits NDP52 to autophagy targets [PDF]

EMBO Journal, 2017
Abstract Autophagy targets intracellular molecules, damaged organelles, and invading pathogens for degradation in lysosomes. Recent studies have identified autophagy receptors that facilitate this process by binding to ubiquitinated targets, including NDP 52.
Atsuko Minowa-Nozawa, Takashi Nozawa, Keiko Okamoto-Furuta   +2 more
exaly   +4 more sources

The Role of Autophagy and Autophagy Receptor NDP52 in Microbial Infections [PDF]

International Journal of Molecular Sciences, 2020
Autophagy is a general protective mechanism for maintaining homeostasis in eukaryotic cells, regulating cellular metabolism, and promoting cell survival by degrading and recycling cellular components under stress conditions. The degradation pathway that is mediated by autophagy receptors is called selective autophagy, also named as xenophagy. Autophagy
Keke Wu, Mingqiu Zhao, Jinding Chen
exaly   +3 more sources

Autophagy Receptor NDP52 Regulates Pathogen-Containing Autophagosome Maturation [PDF]

Cell Host and Microbe, 2015
Xenophagy, an essential anti-microbial cell-autonomous mechanism, relies on the ability of the autophagic process to selectively entrap intracellular pathogens within autophagosomes to degrade them in autolysosomes. This selective targeting is carried out by specialized autophagy receptors, such as NDP52, but it is unknown whether the fusion of ...
Pauline Verlhac, Mathias Fauré
exaly   +4 more sources

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NDP52 GtoE mutation

2021
Collection of simulations and free energy calculations used in the publication: Characterization of a natural variant of human NDP52 and its functional consequences on mitophagy. Di Rita A, Angelini DF, Maiorino T, Caputo V, Cascella R, Kumar M, Tiberti M, Lambrughi M, Wesch N, Löhr F, Dötsch V, Carinci M, D'Acunzo P, Chiurchiù V, Papaleo E, Rogov VV,
Papaleo, Elena, mukesh kumar, , Lambrughi, Matteo, Tiberti, Matteo   +3 more
openaire   +1 more source