Newcastle Disease Virus Fusion and Haemagglutinin-Neuraminidase Gene Divergence: Implications for Vaccines [PDF]
Avian orthoavulavirus 1 (AOaV-1), commonly known as Newcastle disease virus (NDV), despite widespread vaccination, remains a significant threat to domestic chickens (Gallus gallus domesticus).
Ravendra P. Chauhan, Boguslaw Szewczyk
doaj +2 more sources
Research progress on recombinant NDV in cancer therapy. [PDF]
Newcastle disease virus (NDV) has emerged as a promising oncolytic agent in cancer therapy. NDV not only directly lyses tumor cells but also activates the host’s innate and adaptive immune responses, demonstrating potent antitumor activity. However, the efficacy of wild-type NDV is often limited and inconsistent.
Sun J, Wang J, Xiao M, Chen L, Guan Y.
europepmc +4 more sources
NDV-GT wth hyperacute rejection in cancer therapy. [PDF]
Oncolytic viruses (OVs) represent a promising immunotherapy for cancer treatment, though their clinical application is often limited by systemic toxicity and low immunogenicity. To address this, we developed NDV-GT, a genetically engineered Newcastle disease virus that encodes porcine α-1,3-galactosyltransferase.
Li Z, Chen H, Wang Z, Liu X, Qu S.
europepmc +3 more sources
Immune responses to Newcastle disease virus as a minor zoonotic viral agent [PDF]
Summary Newcastle is one of the leading diseases among poultry. The viral agent of this disease is classified in the genus avulavirus of the paramyxovirus family.
Emad Behboudi, Vahideh Hamidi-Sofiani
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Molecular Identification and Phylogenetic Study Based on the Fusion Gene of Newcastle Disease Virus Isolated from Broiler Poultry Farms in Markazi Province, Iran [PDF]
Newcastle disease (ND) is an economically significant and extremely spreadable viral illness affecting a wide variety of avian species. ND can rapidly spread within poultry farms and result in considerable economic losses for the global poultry industry.
V Vahidi, S Ebrahimi, N Akbari, P Jafari
doaj +1 more source
Oncolytic NDV-AMHA1 Strain Effective Against Glioblastoma Cancer Cells [PDF]
Glioblastoma multiforme (GBM) is one of the most life-threatening types of cancer that is difficult to treat. The search for effective yet safe therapy is progressing and non-conventional therapies such as using viruses as a smart and selective agent ...
Zahraa Kadhim +4 more
doaj +1 more source
Assessment of Antiviral Activity for Ethanolic Chlorella vulgaris Extract Against Newcastle Disease Virus (NDV) Infection in Sasso Chicken [PDF]
Newcastle disease (ND) is an extremely viral disease that has tremendous impacts on poultry production worldwide. Increasing and repeating ND outbreaks and suspecting of fifth pandemic occurrence demonstrated the need for novel medicines to control the ...
Reda Fathy +5 more
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This research was aimed to analyze antibody response in laying hens post vaccinated by Newcastle Disease Virus (NDV) recombinat Fusion (F) protein which has been succesfully expressed from the F gene of local isolates of NDV from Kulon Progo strain (0663/
J. Jawad +3 more
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The interference of Newcastle, avian influenza and infectious bursal disease vaccines with the efficiency of IB vaccine in broiler chicks by using quantitative RT-PCR test [PDF]
This study was conducted to investigate the effects the interference of ND, AI, IBD vaccines on efficacy of the IBV vaccination program (H120 and Ma5). Three hundred broiler chicks (Ross308) from Al-Haddi hatchery / Babel province were divided randomly ...
Raed Hussen Saleh, Isam Jaber
doaj +1 more source
Newcastle disease (ND) is a highly contagious viral disease. This study was conducted to determine the antibody titer in Japanese quails following vaccination against ND and feed-supplementation with vitamin-C, probiotics and antibioticgrowth- promoters.
Mirza Mienur Meher +2 more
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