Gamma-irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy. [PDF]
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Kennedy EV +10 more
europepmc +2 more sources
Phylogenetic relationship and genotype variation of six Newcastle disease viruses isolated from duck in Indonesia [PDF]
Background and Aim: Newcastle disease viruses (NDVs) are frequently acquired from all ages and types of bird species. In general, ducks are considered as potential reservoirs for different genotypes of NDV and are resistant even to velogenic NDV strains.
Naimah Putri +4 more
doaj +1 more source
Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Peter E. Marshall +2 more
wiley +1 more source
The Immunomodulatory Activity in vitro of NDV ZG1999HDS in Comparison to NDV La Sota
ABSTRACT. The immunotherapies, as a modern therapeutic approach, get an attention because of theirs’ promise to treat a large number of different medical disorders. Immunomodulation effects of low titres (10 HA/ml) of NDV (Newcastle Disease Virus) ZG1999HDS or La Sota were tested on TLT (Human macrophage cell line) bound to PBMC (Peripheral ...
Bratko Filipič +3 more
openaire +2 more sources
Characterization of Avian Influenza H9N2 and Newcastle Disease Virus Isolated from Vaccinated Chickens in Upper Egypt [PDF]
In this study, 50 vaccinated broiler and one layer flock from Beni-Suef, Fayoum and Minia governorates were investigated. Necropsy lesions were suggestive of LPAI-H9N2 or NDV.
Safaa A. A. Abdel-Latif +4 more
doaj +1 more source
Newcastle disease virus (NDV) threatens global poultry production, with genotype VII the most prevalent strain in China. However, little information is available regarding viral multiplication and pathogenicity based inoculation route.
Xinxin Qiu +4 more
doaj +1 more source
Molecular characterisation of Newcastle disease virus exotic isolate in East Java, Indonesia
Newcastle disease virus (NDV) is ssRNA paramyxovirus causing clinical signs, varying from subclinical infections to 100% mortality in infected chickens. Haemagglutinin-neuraminidase (HN) protein has an important role related to infection and pathogenesis,
N. Kusumarahayu +5 more
doaj +1 more source
This research aimed to express and purify the recombinant Fusion (F) protein of Newcastle Disease Virus (NDV) from a local isolate in Galur, Kulon Progo, Indonesia (0663/04/2013) from recombinant vector plasmid pBT7-N-His F, and to study the antibody ...
R.W. Astuti, N. Wijayanti, A. Haryanto
doaj +1 more source
Newcastle disease virus (NDV) is a member of the Paramyxovirinae subfamily and can infect most species of birds. It has been a great threat for the poultry industry all around the world. In this report, we successfully produced infectious pseudotyped pNL4-3-Luc-R(-)E(-) (HIV-Luc) viruses with the HN and F envelope proteins of NDV. Further investigation
Bin Wang +6 more
openaire +5 more sources
Studies on Hemagglutination by NDV.
Summary and conclusionsBy absorption experiments, a strain of NDV was shown to have at least 2 agglutinins with different specificities. Human RBC were shown to possess receptors for only one type, in contrast to chicken RBC which had receptors for both types.
C J, O'Connell, F, Milgrom
openaire +2 more sources

