Results 31 to 40 of about 2,604,284 (151)

Near infrared photoimmunotherapy targeting DLL3 for small cell lung cancer

EBioMedicine, 2020
Background: Small cell lung cancer (SCLC) has a poor prognosis, and its treatment options are limited. Delta-like protein 3 (DLL3) is expressed specifically in SCLC and is considered a promising therapeutic target for patients with this disease ...
Yoshitaka Isobe, Kazuhide Sato, Yuko Nishinaga, Kazuomi Takahashi, Shunichi Taki, Hirotoshi Yasui, Misae Shimizu, Rena Endo, Chiaki Koike, Noriko Kuramoto, Hiroshi Yukawa, Shota Nakamura, Takayuki Fukui, Koji Kawaguchi, Toyofumi F. Chen-Yoshikawa, Yoshinobu Baba, Yoshinori Hasegawa   +16 more
doaj   +1 more source

Validation of the near infrared spectroscopy method for determining soil organic carbon by employing a proficiency assay for fertility laboratories [PDF]

, 2021
Current research indicates that near infrared (NIR) spectroscopy is the most promising alternative technique for the determination of soil organic carbon (SOC) in laboratories worldwide and that it may serve as a total or partial replacement for the ...
Valderrama, Patrícia, Filgueiras, Paulo Roberto, Fontana, Ademir, Winkler, Thayane Christine Barbosa, Souza, André Marcelo de, Coelho, Maurício Rizzato, Poppi, Ronei Jesus   +6 more
core   +1 more source

The application of near infrared spectroscopy in nutritional intervention studies [PDF]

, 2013
Functional near infrared spectroscopy (NIRS) is a non-invasive optical imaging technique used to monitor cerebral blood flow (CBF) and by proxy neuronal activation.
Kennedy, David, Philippa A Jackson, David O. Kennedy, David O Kennedy, Philippa A. Jackson, Jackson, Philippa   +5 more
core   +1 more source

Evaluation of a Novel Lateral Emitting Laser Fiber for Near-Infrared Photoimmunotherapy [PDF]

Cancers
Motofumi Suzuki, Hisataka Kobayashi, Hirofumi Hanaoka   +2 more
exaly   +2 more sources

Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy

iScience, 2023
Summary: Circulating drugs in the peritoneal cavity is an effective strategy for advanced ovarian cancer treatment. Photoimmunotherapy, an emerging modality with potential for the treatment of ovarian cancer, involves near-infrared light activation of ...
Aaron J. Sorrin, Keri Zhou, Katherine May, Cindy Liu, Kathryn McNaughton, Idrisa Rahman, Barry J. Liang, Imran Rizvi, Dana M. Roque, Huang-Chiao Huang   +9 more
doaj   +1 more source

Photoactivated Platinum Complexes: Targeting Membrane Proteins and Organelles for Precision Cancer Therapy

Angewandte Chemie, EarlyView.
This review highlights an emerging anticancer approach integrating platinum agents into photodynamic therapy (PDT) and photoactivated chemotherapy (PACT) systems, further augmented by cancer cell membrane‐ and organelle‐targeting. By directing photoactivated platinum complexes from nontargeted distribution to cancer cells or defined subcellular sites ...
Shu Chen, Qiyuan Zhou, Jiaqian Xu, Guangyu Zhu   +3 more
wiley   +2 more sources

Quickly evolving near‐infrared photoimmunotherapy provides multifaceted approach to modern cancer treatment

View, 2022
Among modalities of cancer immunotherapy, near‐infrared photoimmunotherapy (NIR‐PIT) has reached significant preclinical and clinical stages and quickly evolved over the last 5 years.
Hailey Monaco, Shinya Yokomizo, Hak Soo Choi, Satoshi Kashiwagi   +3 more
doaj   +1 more source

ALDH Inhibition‐Primed Photocatalysis Disrupts Cancer Stemness Plasticity

Angewandte Chemie, EarlyView.
DE‐Et converts ALDH‐mediated redox buffering into a photoredox vulnerability by coupling ALDH inhibition with red‐light‐driven catalytic NADH oxidation. This enzyme‐coupled photoredox strategy sustains mitochondrial NADH/NAD+ imbalance, induces pyroptotic tumor cell death, suppresses tumor growth in vivo, and promotes systemic antitumor immunity ...
Yujin Kim, Shankun Yao, Ji Hyeon Kim, Rongrong Huang, Hyeonji Rha, Shumeng Li, Kippeum Lee, Yunjie Xu, Xiaogang Liu, Yuncong Chen, Jong Seung Kim   +10 more
wiley   +2 more sources

Gas therapy potentiates aggregation-induced emission luminogen-based photoimmunotherapy of poorly immunogenic tumors through cGAS-STING pathway activation

Nature Communications, 2023
The immunologically “cold” microenvironment of triple negative breast cancer results in resistance to current immunotherapy. Here, we reveal the immunoadjuvant property of gas therapy with cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS ...
Kaiyuan Wang, Yang Li, Xia Wang, Zhijun Zhang, Liping Cao, Xiaoyuan Fan, Bin Wan, Fengxiang Liu, Xuanbo Zhang, Zhonggui He, Yingtang Zhou, Dong Wang, Jin Sun, Xiaoyuan Chen   +13 more
doaj   +1 more source

Pathological features of residual head and neck cancer after near-infrared photoimmunotherapy: implications of an unfavorable tumor immune microenvironment

Photodiagnosis and Photodynamic Therapy
Purpose: Near-infrared photoimmunotherapy has been approved in Japan for unresectable locally advanced or recurrent head and neck cancer. While this therapy theoretically induces selective necrosis of epidermal growth factor receptor-expressing tumor ...
Takuma Makino, Yasuharu Sato, Asami Nishikori, Yuto Naoi, Mizuo Ando   +4 more
doaj   +1 more source