Results 11 to 20 of about 2,604,284 (151)

Near-Infrared Photoimmunotherapy for Oropharyngeal Cancer [PDF]

Cancers, 2022
Human papillomavirus (HPV)-associated oropharyngeal cancer has a better prognosis than other head and neck cancers. However, rates of recurrence and metastasis are similar and the prognosis of recurrent or metastatic HPV-associated oropharyngeal cancer ...
Daisuke Nishikawa, Hidenori Suzuki, Hoshino Terada   +2 more
exaly   +3 more sources

Near-infrared photoimmunotherapy for osteosarcoma targeting epidermal growth factor receptor [PDF]

Translational Oncology
Osteosarcoma is the most common bone tumor, and it possesses high metastatic propensity. Although systemic chemotherapy has improved its prognosis, improvements in survival rates have stalled in recent years.
Motofumi Suzuki, Hisataka Kobayashi, Hirofumi Hanaoka   +2 more
doaj   +2 more sources

Enhancement of drug delivery through fibroblast activation protein–targeted near-infrared photoimmunotherapy [PDF]

JCI Insight
The tumor microenvironment plays a key role in cancer progression and therapy resistance, with cancer-associated fibroblasts (CAFs) contributing to desmoplasia, extracellular matrix (ECM) remodeling, and elevated interstitial fluid pressure, all of which
Seitaro Nishimura, Kazuhiro Noma, Tasuku Matsumoto, Yasushige Takeda, Tatsuya Takahashi, Hijiri Matsumoto, Kento Kawasaki, Hotaka Kawai, Tomoyoshi Kunitomo, Masaaki Akai, Teruki Kobayashi, Noriyuki Nishiwaki, Hajime Kashima, Takuya Kato, Satoru Kikuchi, Shunsuke Tanabe, Toshiaki Ohara, Hiroshi Tazawa, Yasuhiro Shirakawa, Peter L. Choyke, Hisataka Kobayashi, Toshiyoshi Fujiwara   +21 more
doaj   +2 more sources

EpCAM-targeted near-infrared photoimmunotherapy (NIR-PIT) for the treatment of breast cancer [PDF]

Annals of Medicine
Background Near-infrared photoimmunotherapy (NIR-PIT) is a targeted cancer treatment that uses antibody-IR700 conjugates and selectively destroys cancer cells expressing a target antigen when exposed to near-infrared (NIR) light.
Aki Furusawa, Seiichiro Takao, Motofumi Suzuki, Makoto Kano, Hiroshi Yamamoto, Miyu Kano, Peter Choyke, Hisataka Kobayashi   +7 more
doaj   +2 more sources

Targeted Elimination of Influenza Virus and Infected Cells with Near-Infrared Antiviral Photoimmunotherapy (NIR-AVPIT)

Pharmaceutics
Background: Seasonal influenza causes significant morbidity and mortality each year. Since viruses can easily acquire drug-resistant mutations, it is necessary to develop new antiviral strategies with different targets.
Terumi Mizukoshi, Koichiro Tateishi, Mizuki Tokusanai, Yoshiyuki Yoshinaka, Aisaku Yamamoto, Naoki Yamamoto, Norio Yamamoto   +6 more
doaj   +2 more sources

Tissue factor targeted near-infrared photoimmunotherapy: a versatile therapeutic approach for malignancies [PDF]

Cancer Immunology, Immunotherapy
Tissue factor (TF) is a cell surface protein that plays a role in blood clotting but is also commonly expressed in many cancers. Recent research implicated TF in cancer proliferation, metastasis, angiogenesis, and immune escape.
Seiichiro Takao, Hiroshi Fukushima, Aki Furusawa, Takuya Kato, Shuhei Okuyama, Makoto Kano, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Peter L. Choyke, Hisataka Kobayashi   +10 more
doaj   +2 more sources

Combined CD25-targeted near infrared photoimmunotherapy (NIR-PIT) and intratumor IL-15 enhance the effectiveness of anti-PD-1 immunotherapy [PDF]

Cancer Immunology, Immunotherapy
Immunotherapies aimed at enhancing anti-cancer immunity are now in wide clinical use. For instance, anti-programmed cell death protein 1 (PD-1) monoclonal antibody (mAb) therapy has demonstrated clinical efficacy in many tumor types, but overall, only a ...
Makoto Kano, Aki Furusawa, Hiroshi Fukushima, Seiichiro Takao, Shuhei Okuyama, Hiroshi Yamamoto, Motofumi Suzuki, Miyu Kano, Ko Kitamura, Peter L. Choyke, Hisataka Kobayashi   +10 more
doaj   +2 more sources

Adding Intratumoral Antibody-Photoabsorber Conjugate Improves Efficacy of Near-Infrared Photoimmunotherapy (NIR-PIT). [PDF]

Cancer Sci
Intravenous (IV) or intratumoral (IT) cetuximab distribution in A431 tumor (essence of Figure 2). ABSTRACT Near‐infrared photoimmunotherapy (NIR‐PIT) is a new type of cancer treatment that specifically kills target cells while sparing normal tissue. This treatment induces cancer cell death by activating a photoreactive dye with near‐infrared light in ...
Kano M, Furusawa A, Takao S, Kano M, Suzuki M, Yamamoto H, Okuyama S, Kitamura K, Choyke PL, Kobayashi H.   +9 more
europepmc   +2 more sources

Portable microcontroller-based instrument for near-infrared spectroscopy [PDF]

, 2000
Near Infrared Spectroscopy (NIRS) can be employed to noninvasively and continuously measure in-vivo local changes in haemodynamics and oxygenation of human tissues.
Giardini, Mario Ettore, Lago, Paolo, Corti, Mario, Gelmetti, Andrea   +3 more
core   +4 more sources

Near-infrared spectra of aqueous glucose solutions [PDF]

, 2022
Infrared spectroscopy is widely utilized in the scientific community for chemical characterization of materials. Near-infrared spectroscopy relies on spectral measurements between 900 and 2,500 nm.
Lee, Tse-Ang, Peng, Jessie, Hutter, Tanya   +2 more
core   +1 more source