Results 91 to 100 of about 47,289 (162)

Significance of Necroptosis in Cartilage Degeneration

Cartilage, a critical tissue for joint function, often degenerates due to osteoarthritis (OA), rheumatoid arthritis (RA), and trauma. Recent research underscores necroptosis, a regulated form of necrosis, as a key player in cartilage degradation.
Jea-Hoon Kim, Young-Yul Kim, Md Abdul Khaleque, Md Amit Hasan Tanvir, Jong-Beom Park   +4 more
core   +1 more source

Induced Necroptosis and Its Role in Cancer Immunotherapy

Necroptosis is a type of regulated cell death (RCD) that is triggered by changes in the extracellular or intracellular milieu that are picked up by certain death receptors.
Ziyao Zhang, Xing Wang, Fangming Zhang, Wenjing Xie, Yubo Niu, Lingyun Zhao, Wensheng Xie, Guofeng Li, Haonan Wang   +8 more
core   +1 more source

Lytic cell death in chronic lung diseases. [PDF]

Am J Respir Cell Mol Biol
Siokas I, Heileman M, Fritz LC, Degterev A.   +3 more
europepmc   +1 more source

TNF-induced lethality occurs independently of NLRP3 inflammasome signaling. [PDF]

Signal Transduct Target Ther
Riebeling T, von Samson-Himmelstjerna FA, Kolbrink B, Schmitt R, Krautwald S.   +4 more
europepmc   +1 more source

Exogenous hydrogen sulfide alleviates cerebral ischemia/reperfusion injury via inhibiting RIPK1-mediated neuronal necroptosis and ROS overaccumulation. [PDF]

Front Mol Biosci
Huang C, Shang H, Fang Z, Zhu L, Chen C, Zang Y.   +5 more
europepmc   +1 more source

z-VAD-FMK triggers macrophage necroptosis during mycobacterial infection via a non-canonical off-target mechanism. [PDF]

mLife
Hu R, Li P, Han J, Huang J, Huang G, Jiang X, Pfau D, Li G, Gong YN, Nathan CF, Zhang L.   +10 more
europepmc   +1 more source

LILRB4 Attenuates Ischemic Brain Injury by Inhibiting Microglial Necroptosis via a RIPK3-Dependent Mechanism. [PDF]

Glia
Hu J, Zhang M, Liu P, Chen Y, Meng H, Xia S, Bao X, Xu Y, Chen Y.   +8 more
europepmc   +1 more source

Small Molecule Conjugation of Hsp70 Inhibits Necroptosis

, 2018
Necroptosis is a subtype of regulated necrosis in which signaling through receptor interacting protein kinase 3 (RIPK3) triggers caspase independent, immunogenic cell death morphologically identical to necrosis. Necroptosis is physiologically relevant in
Johnston, Andrea N.
core  

RIPK1 in Alzheimer's Disease: A Context-Dependent Signaling Hub Linking Aβ, Tau, Neuroinflammation, and Regulated Cell Death. [PDF]

Cells
Caccamo A, Lanza M, Casili G, Oddo S.
europepmc   +1 more source

Identification of a necroptosis-related lncRNA prognostic signature and the hub RBP HNRNPK in esophageal squamous cell carcinoma. [PDF]

J Int Med Res
Zheng S, Yang H, Liu W, Zhi F, Luo H, Feng Y, Lei Y.   +6 more
europepmc   +1 more source