Results 261 to 270 of about 51,913 (289)

Rhein protects against renal aging and fibrotic injury by multiple targets through inhibition of TNF-α-mediated autophagy and necroptosis crosstalk. [PDF]

Front Pharmacol
Tu Y, Liu W, Sang T, Pan L, Wu W, Fang Q, Liu Y, Liu B, Wan Y.   +8 more
europepmc   +1 more source

Beyond IHC Stain: Mitochondria as a Histochemical Biomarker for Apoptosis Detection in Hepatic Tissue Sections

Anatomia, Histologia, Embryologia, Volume 55, Issue 2, March 2026.
ABSTRACT Apoptosis plays a critical role in maintaining tissue homeostasis and preventing pathological conditions. The accurate detection of apoptosis is crucial for both research and diagnostic pathology, yet conventional histological staining methods often lack the sensitivity to identify early apoptotic changes.
Maria‐Cătălina Matei‐Lațiu, Andreea Muntean, Vasile Rus, Adrian Florin Gal   +3 more
wiley   +1 more source

NLK facilitates Caspase-8 activation to drive macrophage PANoptosis in sepsis. [PDF]

Clin Transl Med
Xia Y, Yao RQ, Liu HF, Jing GQ, Aidebaike D, Zuo J, Wan SQ, Wu D, Zhao PY, Gong HL, Wang X, Zhou HM, Dong N, Wu Y, Liu S, Wu XJ, Yao YM, Song XM.   +17 more
europepmc   +1 more source

The impact of Foxp3+ regulatory T‐cells on CD8+ T‐cell dysfunction in tumour microenvironments and responses to immune checkpoint inhibitors

British Journal of Pharmacology, Volume 183, Issue 6, Page 1250-1270, March 2026.
Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley   +1 more source

Mitochondrial homeostasis meets novel programmed cell death: crosstalk mechanisms underlying cardiovascular diseases progression. [PDF]

Cell Commun Signal
Li M, Zhang Y, Hu Y, Qin Y, Zheng Y, Lv S, Zhang J.   +6 more
europepmc   +1 more source

Synaptotagmin-7 drives stress-induced cardiomyocyte necroptosis via the p53-Bak-mPTP axis. [PDF]

Theranostics
Li J, Wang S, Han Y, Liu J, Li Y, Zhang J, Guo L, Jin Y, Chang J, Liu T, Zhou L, Liu S, Yang G, Zhang S, Cao J, Na J, Sun T.   +16 more
europepmc   +1 more source

Ginseng Polysaccharides Protect Against Endoplasmic Reticulum Stress-Induced Damage via PI3K/Akt Signalling Pathway in Bovine Ovarian Granulosa Cells. [PDF]

Cells
Wang H, Fang Y, Huang L, Yang X, Ma X, Lyu Y, Jing G, Ding H, Liu H, Lyu W.   +9 more
europepmc   +1 more source

The Potential Clinical Relevance of Necrosis-Necroptosis Pathways for Hypoxic-Ischaemic Encephalopathy. [PDF]

Cells
Lear BA, McDouall AJ, Lear OJ, Dhillon SK, Lear CA, Northington FJ, Bennet L, Gunn AJ.   +7 more
europepmc   +1 more source

ZBP1 Mediates Renal Tubular Injury in Diabetic Nephropathy Through RIPK3-mediated Necroptosis. [PDF]

Inflammation
Hu Z, Ma Y, Wang Y, Wang J, Liu X, Chen C, Zhu W, Qi X, Wu Y.   +8 more
europepmc   +1 more source

ZBP1 as a dynamic monitor of viral replication: implications for therapeutic strategies. [PDF]

Front Cell Infect Microbiol
Ou Z, Huang Y, Xue X, Zhou H, Li S, Xiao K.   +5 more
europepmc   +1 more source