Results 11 to 20 of about 6,858 (167)
Statin-Induced Necrotizing Autoimmune Myopathy
JACC: Case Reports, 2020 Statin-induced necrotizing autoimmune myopathy (SINAM) is an exceptionally rare yet devastating complication of statin therapy that can occur at any time after initiation.
Brent Gawey, BS +4 more
doaj +6 more sources
Necrotizing autoimmune myopathy
Annals of Indian Academy of Neurology, 2016 Abstract Necrotizing autoimmune myopathy (NAM) is a recently recognized entity within the spectrum of idiopathic inflammatory myopathies. Diagnosis critically rests on histopathologic demonstration of macrophage predominant myocyte destruction, with few to no lymphocytes.
Sachin Suresh Babu +5 more
doaj +6 more sources
Necrotizing Autoimmune Myopathy: A Rare Variant of Idiopathic Inflammatory Myopathies [PDF]
Journal of Investigative Medicine High Impact Case Reports, 2017 Idiopathic inflammatory myopathies are an unusual group of myopathies with annual incidence of 1 in 100 000 people in the United States. Necrotizing autoimmune myopathy comprises only 16% of this group.
Noman Ahmed Jang Khan MD +4 more
doaj +3 more sources
Treatment of refractory immune-mediated necrotizing myopathy with efgartigimod [PDF]
Frontiers in ImmunologyYun Yuan, Yikang Wang, Hao Hongjun
exaly +2 more sources
Statins and muscle – friends or foes? Discussions based on a case report [PDF]
Romanian Journal of Rheumatology, 2022 Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infrequent extra-muscular involvement ...
Andra Patricia Stanciu +2 more
doaj +1 more source
Severe Anti-HMG-CoAR Necrotizing Autoimmune Myopathy Secondary to Statin Use
Case Reports in Rheumatology, 2022 Immune-mediated necrotizing myopathy is an uncommon but debilitating disease that can be triggered by drugs, toxins, or cancer. It is similar to polymyositis in presentation but is differentiated by findings on muscle biopsy.
Priyanjali Pulipati +2 more
doaj +1 more source
Immune-Mediated Necrotizing Myopathy [PDF]
Current Rheumatology Reports, 2018 Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune myopathy characterized by relatively severe proximal weakness, myofiber necrosis with minimal inflammatory cell infiltrate on muscle biopsy, and infrequent extra-muscular involvement. Here, we will review the characteristics of patients with IMNM.Anti-signal recognition particle (SRP ...
Iago, Pinal-Fernandez +2 more
openaire +2 more sources
Diagnosis of Statin-Induced Necrotizing Myopathy: Contribution of Anti-HMGCR Antibodies
Acta Médica Portuguesa, 2022 Over the last few years, several cases of statin-induced necrotizing myopathy have been described. This myopathy is characterized by the necrosis of muscle fibers and the presence of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR ...
Cláudia Fidalgo +3 more
doaj +1 more source
SAGE Open Medical Case Reports, 2020 Anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) immune-mediated necrotizing myopathy is a subtype of idiopathic inflammatory myopathy which may be associated with statin exposure.
Darosa Lim +6 more
doaj +1 more source
Treatment of Immune-Mediated Necrotizing Myopathy. [PDF]
Curr Treatm Opt Rheumatol, 2023 Immune-mediated necrotizing myositis (IMNM) is a rare autoimmune disorder characterized by proximal muscle weakness, elevated creatine kinase levels, and necrosis of muscle fibers. While the exact pathogenesis of IMNM remains unknown, anti-HMGCR and anti-SRP autoantibodies are associated with different predisposing factors, clinical manifestations, and
Ogbonnaya-Whittlesey SA +4 more
europepmc +4 more sources