Results 21 to 30 of about 6,858 (167)
Journal of the Saudi Heart Association, 2019 A well-known side effect of statin therapy is myopathy. We report a case of statin induced necrotizing autoimmune myopathy, a rare variant of statin-induced myopathy. A 64-year-old gentleman on atorvastatin presented with muscle weakness.
Yehia Saleh +3 more
doaj +1 more source
Autoimmune statin-induced myopathy: a case report [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2015 A 58-year-old woman with a history of statin use presented with a 4-month history of progressive weakness of both shoulders and thighs. Laboratory and electromyography testing confirmed the presence of generalized proximal myopathy and ruled out ...
Jonathan B. Young, Ibrahim I. Ghobrial
doaj +1 more source
Current Opinion in Rheumatology, 2014 This review discusses the spectrum of diseases associated with a necrotizing muscle biopsy. Although patients with toxic myopathies, endocrine dysfunction, and heritable myopathies may have prominent necrosis on muscle biopsy, immune-mediated myopathies are emphasized here.A decade ago, immune-mediated necrotizing myopathy was recognized as a distinct ...
openaire +3 more sources
Thrombosis Journal, 2021 Background Immune-mediated necrotizing myopathy (IMNM) is characterized by proximal muscle weakness, elvated serum muscle enzyme levels, myopathic electromyography findings, and necrotic muscle fiber with few inflammatory cell infiltration in muscle ...
Jiali Li +5 more
doaj +1 more source
Paraneoplastic necrotizing myopathy – a case report
Revista Brasileira de Reumatologia, 2017 Alberto Pereira Ferraz +1 more
doaj +3 more sources
Immune-Mediated Necrotizing Myopathy: An Often Misdiagnosed Entity
European Journal of Case Reports in Internal Medicine, 2015 Immune-mediated necrotizing myopathies (IMNM) are recognized as a subgroup of idiopathic inflammatory myopathies (IIM). IMNM are defined based on a combination of clinical presentation and laboratory studies, requiring a specific myopathological pattern ...
Joana Almeida Espírito Santo +4 more
doaj +1 more source
Journal of Clinical Rheumatology and Immunology, 2019 We report here a statin naive lady who had refractory myositis for years. The diagnosis was revised to be anti-HMGCR related immune mediated necrotizing myopathy after repeating the muscle biopsy and checking the autoantibody.
Lucas Luk, Ho So
doaj +1 more source
Statin-induced necrotizing autoimmune myopathy: a systematic review
Rheumatology, 2022 Statins are a class of lipid-lowering medications used worldwide by millions of people and are safe for frequent use in most patients. However, they cause necrotizing autoimmune myopathy in some patients. We reviewed case reports of 80 patients from 2010
Manoj Reddy Somagutta +9 more
doaj +1 more source
Severe Recurrent Necrotizing Myopathy in Pregnancy: A Case Report
Frontiers in Neurology, 2018 Pregnancy in patients with necrotizing autoimmune myopathy without identified antibodies is rarely reported. We report a case involving a 26-year-old woman with antibody-negative autoimmune necrotizing myopathy who experienced a relapse during pregnancy.
Yue Li +5 more
doaj +1 more source
Necrotizing autoimmune myopathy with tubular aggregates [PDF]
Neurology, 2019 The formation of tubular aggregates (TA) within muscle fibers has been associated with toxic, metabolic, and hereditary myopathies, congenital myasthenic syndromes (CMS),1 and recently with pembrolizumab-associated myopathy.2 On electron microscopy, TA have the appearance of parallel tubules in crystalline arrangements, and are continuous extensions of
Nicolas N, Madigan +3 more
openaire +2 more sources