Results 31 to 40 of about 7,212 (106)

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, Volume 25, Issue 21-22, Page 102-150, November 2025.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

Abstracts From AIDS 2026, the 26th International AIDS Conference, 26 – 31 July 2026 Rio de Janeiro, Brazil & virtual

Journal of the International AIDS Society, Volume 29, Issue S4, July 2026.
wiley   +1 more source

ISEV2026 Abstract Book

Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

Replication-competent SIVcpz CRISPR screen identifies barriers to successful cross-species transmission. [PDF]

J Virol
Xie Q, Wang Q, Noettger S, Gosálbez G, Betzler AC, Volcic M, Kmiec D, Krebs S, Graf A, Gülensoy D, Weidinger G, Sparrer KMJ, Kirchhoff F.   +12 more
europepmc   +2 more sources

Hyper-responsiveness to stimulation of human immunodeficiency virus-infected CD4+ T cells requires Nef and Tat virus gene products and results from higher NFAT, NF-κB, and AP-1 induction. Vol. 279 (2004) 39520–39531

Journal of Biological Chemistry, 2005
Jean-François Fortin, Corinne Barat, Yannick Beauséjour, Benoit Barbeau, Michel J. Tremblay   +4 more
openaire   +1 more source

An immunofluorescence microscopy assay to discriminate distinct expression patterns of HIV-1 Gag and Nef proteins in HIV-1 provirus-harboring cells. [PDF]

PLoS One
Wiscovitch-Russo R, Sui H, Smith M, Imamichi H, Lane HC, Imamichi T.   +5 more
europepmc   +1 more source

HIV Nef-mediated WAVE2-ARP2/3 inhibition underlies CD4⁺ T-cell lamellipodial abnormalities and immune dysfunction. [PDF]

mBio
Dunn DC, Crater JM, Del Río Estrada PM, Malgady JM, Haas G, Klain W, Torres-Ruiz MF, Luna-Villalobos YA, González-Navarro M, Kang C, Kovacs C, Ávila-Ríos S, Lee B, Jolicoeur P, Nixon DF, Furler O'Brien RL.   +15 more
europepmc   +1 more source

Ancestral reconstruction supports that loss of Nef-mediated T cell modulation coincided with the emergence of pathogenic lentiviruses. [PDF]

J Virol
Baldino AM, Mumby MJ, Edgar CR, Olabode AS, Poon AFY, Dikeakos JD.   +5 more
europepmc   +1 more source

Administration of Nicotinamide Mononucleotide Mitigates the HIV Nef-Induced Metabolic and Pathological Changes in the Heart. [PDF]

Cells
Kondrachuk O, Nakhungu E, Ogundipe G, Tailor N, Ciccone P, Hong K, Gadiraju A, Kimura Y, Zi A, Yusuf S, Alkousa A, Nguyen S, Rajkumar R, Do J, Rappaport J, Gupta MK.   +15 more
europepmc   +1 more source

Turning defense into damage: HIV-driven amyloidogenesis and neurotoxicity. [PDF]

mBio
Gu F, Saed B, Naghavi MH.
europepmc   +1 more source