Fatty liver is closely associated with elevated concentrations of nonesterified fatty acids (NEFA) and a low level of very low-density lipoproteins (VLDL) in blood of dairy cows.
Dongmei Xing+8 more
doaj +1 more source
The Correlation between Extracellular Heat Shock Protein 70 and Lipid Metabolism in a Ruminant Model
Metabolic stress in early lactation cows is characterized by lipolysis, ketogenesis, insulin resistance and inflammation because of negative energy balance and increased use of lipids for energy needs.
Miloš Ž. Petrović+7 more
doaj +1 more source
Effects of obesity-associated plasma markers on adipose stem cell function and epigenetic regulation. [PDF]
Abstract Objective This study investigates the correlations between obesity‐related plasma markers and epigenetic/inflammatory changes in white adipose tissue (WAT), focusing on adipose‐derived stem cells (ASCs). We hypothesize that obesity modulates histone H3K27 marks, modified by demethylases (lysine‐specific demethylase 6A and 6B [KDM6A/KDM6B]) and
Bispo AFS+9 more
europepmc +2 more sources
Acute effects of meal fatty acids on postprandial NEFA, glucose and apo E response: implications for insulin sensitivity and lipoprotein regulation? [PDF]
Our aim was to determine whether meal fatty acids influence insulin and glucose responses to mixed meals and whether these effects can be explained by variations in postprandial NEFA and Apo, which regulate the metabolism of triacylglycerol-rich ...
Kim G. Jackson+4 more
openalex +2 more sources
U Cinn - NEFA Concentration v1 [PDF]
Summary: Quantitative determinations of non-esterified fatty acids in plasma/serum/lymph will be made using the NEFA-HR enzymatic colorimetric method assay.
Patrick Tso, Dana Lee
openaire +2 more sources
Moderate exercise increases affinity of large very low density lipoproteins for hydrolysis by lipoprotein lipase [PDF]
Context: Postprandial triglyceride (TG) concentration is independently associated with cardiovascular disease risk. Exercise reduces postprandial TG concentrations but the mechanisms responsible are unclear.
Bedford, Dorothy K.+5 more
core +1 more source
Type 2 diabetes mellitus (T2DM) is a group of metabolic disorders characterized by hyperglycemia owing to insulin resistance and/or insulin deficiency.
M. Saad, M. Kamel, M. Hanafi
semanticscholar +1 more source
Effect of Insulin on Rate of Hepatic Uptake of NEFA.
SummaryConcentrations of NEFA in plasma of blood obtained from splenic artery, portal and hepatic veins were measured in un-anesthetized dogs together with hepatic plasma flow. Rates of hepatic and non-hepatic splanchnic uptake or output of NEFA were calculated before and after insulin administration. A marked increase in rate of hepatic uptake of NEFA
William C. Shoemaker+3 more
openaire +3 more sources
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State. [PDF]
In metabolic diseases such as Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease, the systemic regulation of postprandial metabolite concentrations is disturbed.
Fianne L P Sips+6 more
doaj +1 more source
Fatty acid profile of plasma NEFA does not reflect adipose tissue fatty acid profile
Adipose tissue (AT) fatty acid (FA) composition partly reflects habitual dietary intake. Circulating NEFA are mobilised from AT and might act as a minimally invasive surrogate marker of AT FA profile.
C. Walker+6 more
semanticscholar +1 more source