High-fat diet induces senescence in ADSCs via CDK4 ubiquitination-mediated cell cycle disruption, contributing to impaired glucose tolerance. [PDF]
Ge Z +9 more
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Pioglitazone with SGLT2 inhibitors or GLP-1 receptor agonists in patients with type 2 diabetes and non-alcoholic fatty liver disease: could the combinations of an old friend with new players yield better outcomes? [PDF]
Papaetis GS, Picolos MK, Sacharidou A.
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Feeding and plasma NEFA levels in newborn infants
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From Adipose Dysfunction to Multi-Organ Steatosis: Defining the Metabolic Steatotic Axis. [PDF]
Fajkić A +5 more
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Avian GCGR-mediated continuous fat utilization offers perspectives for obesity treatment. [PDF]
Zhang C +18 more
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The regulation of intrahepatic fatty acid partitioning within the human liver: the effect of sex. [PDF]
Dennis KMJH +3 more
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Origin of the NEFA and Nuc Signal Sequences
Journal of Molecular Evolution, 1998The human protein NEFA binds calcium, contains a leucine zipper repeat that does not form a homodimer, and is proposed (along with the homologous Nuc protein) to have a common evolutionary history with an EF-hand ancestor. We have isolated and characterized the N-terminal domain of NEFA that contains a signal sequence inferred from both endoproteinase ...
A, Karabinos +3 more
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THE KETOTIC RATIO (KB/NEFA) IN MAN
Clinical and Experimental Pharmacology and Physiology, 1981SUMMARY1. The ‘ketotic ratio’, which is defined as the plasma ketone‐body concentration divided by the plasma nonesterified fatty acid concentration, is potentially useful in predicting the magnitude of the ketone response to a given increment in plasma fatty acid concentration.2. Two parameters of the ketotic ratio were studied. First, a comparison of
D S, Schade, R P, Eaton
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A Model of NEFA Dynamics with Focus on the Postprandial State
Annals of Biomedical Engineering, 2009To improve the understanding of the mechanisms underlying the behavior of plasma non-esterified fatty acids (NEFA) in the postprandial state, we have developed a physiology-based mathematical model of plasma NEFA dynamics. Known physiological mechanisms are quantified and used to describe NEFA dynamics. Insulin is the major regulator of NEFA metabolism
Jelic, Katarina +2 more
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